Development Level

Tchem 6 | 1,598
Tbio 2 | 11,445

IMPC Phenotype

abnormal embryo size 1 | 220
abnormal eye morphology 1 | 68
decreased vertical activity 1 | 208
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278

Disease

Carcinoma 8 | 11,493
osteosarcoma 6 | 7,950
ovarian cancer 6 | 8,520
Breast cancer 5 | 3,578
Cancer 5 | 2,499
Atrial Septal Defects 4 | 85
Blepharoptosis 4 | 231
Dull intelligence 4 | 645
Intellectual disability 4 | 1,016
Kidney cancer 4 | 2,613
Low intelligence 4 | 645
Low set ears 4 | 181
Mental Retardation 4 | 645
Mental deficiency 4 | 645
Muscle hypotonia 4 | 571
Poor school performance 4 | 645
Small head 4 | 374
Strabismus 4 | 270
Ventricular Septal Defects 4 | 119
lung cancer 4 | 4,740
psoriasis 4 | 6,694
Acquired scoliosis 3 | 281
Adenoid Cystic Carcinoma 3 | 99
Agenesis of corpus callosum 3 | 83
Byzanthine arch palate 3 | 194
Carcinoma, Adenoid Cystic 3 | 99
Cardiac Arrhythmia 3 | 103
Cardiac conduction abnormalities 3 | 78
Cognitive delay 3 | 608
Conduction disorder of the heart 3 | 79
Congenital Epicanthus 3 | 177
Congenital deafness 3 | 185
Cryptorchidism 3 | 296
Curvature of spine 3 | 282
Deafness 3 | 198
Delayed bone age 3 | 136
Delayed speech and language development 3 | 112
Downward slant of palpebral fissure 3 | 158
EKG abnormalities 3 | 78
Electrocardiogram abnormal 3 | 81
Electrocardiogram change 3 | 78
Epilepsy 3 | 792
Exophthalmos 3 | 112
Feeding difficulties in infancy 3 | 175
Global developmental delay 3 | 608
Hearing Loss, Partial 3 | 185
Hypoplastic mandible condyle 3 | 275
Language Delay 3 | 112
Laryngomalacia 3 | 14
Low posterior hairline 3 | 52
Mandibular hypoplasia 3 | 275
Mental and motor retardation 3 | 608
Micrognathism 3 | 275
Patent ductus arteriosus 3 | 90
Pectus excavatum 3 | 100
Polyhydramnios 3 | 108
Prominent eyes 3 | 96
Prominent globes 3 | 96
Protruding eyes 3 | 96
Respiratory distress 3 | 43
Schizophrenia 3 | 1,160
Seizures 3 | 596
Short stature 3 | 531
Speech Delay 3 | 112
Speech impairment 3 | 112
group 3 medulloblastoma 3 | 4,104
hearing impairment 3 | 199
medulloblastoma, large-cell 3 | 6,241
Agoraphobia 2 | 21
Auricular malformation 2 | 41
Broad thumbs 2 | 28
Carcinoma, Squamous Cell 2 | 110
Convex nasal bridge 2 | 57
Corneal abnormalities 2 | 6
Cornela disease 2 | 6
Decreased projection of maxilla 2 | 66
Deficiency of upper jaw bones 2 | 66
Dental Enamel Hypoplasia 2 | 43
Duane Retraction Syndrome 2 | 13
Enophthalmos 2 | 75
Flared iliac wings 2 | 13
Hirsutism 2 | 47
Hyperactive behavior 2 | 91
Hyperplasia of foramen magnum 2 | 6
Hypoplasia of the maxilla 2 | 66
Hypotrophic maxilla 2 | 66
Inadequate arch length for tooth size 2 | 45
Increased circumference of foramen magnum 2 | 6
Increased diameter of foramen magnum 2 | 6
Large foramen magnum 2 | 6
Maxillary retrognathia 2 | 66
Poor coordination 2 | 11
Prominent nasal bridge 2 | 57
Recurrent upper respiratory tract infection 2 | 21
Retrusion of upper jaw bones 2 | 66
Self Mutilation 2 | 14
Simple ear 2 | 41
Spina bifida occulta 2 | 19
Sunken eyes 2 | 63
Tooth mass arch size discrepancy 2 | 45

Tissue

Blood and immune system 8 | 16,909
Digestive Tract 8 | 17,369
Female tissues 8 | 17,400
Liver and Pancreas 8 | 16,750
Male tissues 8 | 17,142
Skin and soft tissues 8 | 17,230
Urinary Tract 8 | 16,678
Cardiovascular System 7 | 15,192
Endocrine System 7 | 18,159
Nervous System 7 | 16,725
Respiratory system 7 | 16,393

Target Family

Epigenetic 7 | 242
Enzyme 1 | 4,145

GO Function

acetyltransferase activity 8 | 8
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Histone acetyltransferase KAT6B KAT6B Tbio Epigenetic -2.30232 201.0 58
Histone acetyltransferase p300 EP300 Tchem Epigenetic -3.79743 6016.7 775
2-acylglycerol O-acyltransferase 2 MOGAT2 Tchem Enzyme -1.12552 13.3 106
Histone acetyltransferase KAT2B KAT2B Tchem Epigenetic -2.62847 372.0 331
Histone acetyltransferase KAT5 KAT5 Tchem Epigenetic -2.29449 194.7 504
Histone acetyltransferase KAT6A KAT6A Tbio Epigenetic -2.00538 107.9 86
CREB-binding protein CREBBP Tchem Epigenetic -2.81657 471.6 449
Histone acetyltransferase KAT8 KAT8 Tchem Epigenetic -2.31028 198.4 195