Development Level

Tbio 19 | 11,445
Tdark 7 | 6,588
Tchem 3 | 1,598
Tclin 3 | 613

Collection

Ion Channel: IDG Consortium (T... 1 | 99

IMPC Phenotype

abnormal hair growth 1 | 10
abnormal kidney morphology 1 | 65
abnormal lens morphology 1 | 81
abnormal pelvic girdle bone mo... 1 | 12
cataract 1 | 92
decreased caudal vertebrae num... 1 | 53
decreased circulating triglyce... 1 | 79
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular vol... 1 | 79
decreased total body fat amoun... 1 | 207
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
hypoactivity 1 | 132
increased circulating calcium ... 1 | 34
increased circulating serum al... 1 | 22
increased monocyte cell number 1 | 63
increased neutrophil cell numb... 1 | 46
preweaning lethality, complete... 1 | 979
thrombocytosis 1 | 27

Disease

ovarian cancer 20 | 8,520
glioblastoma 18 | 5,792
osteosarcoma 18 | 7,950
Carcinoma 17 | 11,493
medulloblastoma, large-cell 17 | 6,241
atypical teratoid / rhabdoid tumor 16 | 5,112
non-small cell lung cancer 11 | 2,890
psoriasis 11 | 6,694
Breast cancer 10 | 3,578
adult high grade glioma 10 | 3,801
lung cancer 10 | 4,740
ependymoma 9 | 4,679
group 3 medulloblastoma 9 | 4,104
lung adenocarcinoma 8 | 2,716
cystic fibrosis 7 | 1,696
interstitial cystitis 7 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 7 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,291
pancreatic cancer 7 | 2,398
primitive neuroectodermal tumor 7 | 3,035
Cancer 6 | 2,499
adrenocortical carcinoma 6 | 1,428
invasive ductal carcinoma 6 | 2,951
juvenile dermatomyositis 6 | 1,187
lung carcinoma 6 | 2,843
oligodendroglioma 6 | 2,850
Astrocytoma, Pilocytic 5 | 3,081
Kidney cancer 5 | 2,613
Multiple myeloma 5 | 1,332
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
malignant mesothelioma 5 | 3,232
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
pediatric high grade glioma 5 | 1,064
pituitary cancer 5 | 1,972
spina bifida 5 | 1,074
tuberculosis 5 | 2,010
Autosomal recessive predisposition 4 | 1,442
Liddle syndrome 4 | 14
Pick disease 4 | 1,894
astrocytic glioma 4 | 2,597
autosomal dominant Emery-Dreifuss muscular dystrophy 4 | 510
group 4 medulloblastoma 4 | 1,855
pancreatic carcinoma 4 | 562
Bronchiectasis 3 | 64
Bronchitis, Chronic 3 | 12
Dehydration 3 | 40
Diarrhea 3 | 253
Duchenne muscular dystrophy 3 | 601
Edema 3 | 81
Failure to gain weight 3 | 365
Feeding difficulties in infancy 3 | 175
Hyperactive renin-angiotensin system 3 | 8
Hyperaldosteronism 3 | 35
Hyperkalemia 3 | 17
Hypertension 3 | 396
Hypertensive disease 3 | 292
Hypertensive disorder 3 | 56
Hypokalemia Prevention 3 | 6
Hyponatremia 3 | 25
Hypotension 3 | 82
Idiopathic bronchiectasis 3 | 4
Increased plasma renin activity 3 | 8
Infantile onset 3 | 238
Kidney disease 3 | 430
Metabolic acidosis 3 | 90
Pediatric failure to thrive 3 | 365
Peripheral Edema due to Chronic Heart Failure 3 | 10
Pseudohypoaldosteronism 3 | 23
Pseudohypoaldosteronism, Type I, Autosomal Recessive 3 | 3
Pulmonary Edema due to Chronic Heart Failure 3 | 6
Recurrent respiratory infections 3 | 141
Renal salt wasting 3 | 18
Vomiting 3 | 116
active Crohn's disease 3 | 922
aldosterone-producing adenoma 3 | 665
autosomal recessive pseudohypoaldosteronism type 1 3 | 3
dermatomyositis 3 | 966
ductal carcinoma in situ 3 | 1,745
esophageal adenocarcinoma 3 | 737
subependymal giant cell astrocytoma 3 | 2,287
Amyotrophic lateral sclerosis 2 | 451
Brain Ischemia 2 | 110
Decreased tendon reflex 2 | 122
Distal limb muscle weakness due to peripheral neuropathy 2 | 62
Distal muscle weakness 2 | 62
Down syndrome 2 | 499
Endometriosis 2 | 540
Kidney Failure 2 | 111
Neurodegenerative disease 2 | 414
Neuropathy 2 | 261
Renal Insufficiency 2 | 90
Renal failure in adulthood 2 | 76
acute quadriplegic myopathy 2 | 1,158
adrenocortical adenoma 2 | 131
astrocytoma 2 | 1,146
breast carcinoma 2 | 1,638
colon cancer 2 | 1,478
fibroadenoma 2 | 559
nasopharyngeal carcinoma 2 | 1,058
primary pancreatic ductal adenocarcinoma 2 | 1,109

Tissue

Blood and immune system 32 | 16,909
Digestive Tract 32 | 17,369
Endocrine System 32 | 18,159
Female tissues 32 | 17,400
Liver and Pancreas 32 | 16,750
Male tissues 32 | 17,142
Nervous System 32 | 16,725
Respiratory system 32 | 16,393
Skin and soft tissues 32 | 17,230
Urinary Tract 32 | 16,678
Cardiovascular System 27 | 15,192

Target Family

Non-IDG 24 | 12,091
Ion Channel 3 | 344
Transcription Factor 3 | 1,400
Enzyme 1 | 4,145
Kinase 1 | 634

GO Function

WW domain binding 32 | 32
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Kinesin-like protein KIF20B KIF20B Tbio Non-IDG -1.04680 12.5 48
Transcription elongation factor A protein-like 7 TCEAL7 Tbio Non-IDG -0.70919 5.68 38
Rap guanine nucleotide exchange factor 2 RAPGEF2 Tbio Non-IDG -1.41107 29.0 79
NEDD4 family-interacting protein 2 NDFIP2 Tbio Non-IDG -0.67951 5.49 37
TNF receptor-associated factor 4 TRAF4 Tbio Non-IDG -1.67380 54.4 234
Caytaxin ATCAY Tbio Non-IDG -1.07937 14.4 48
NEDD4 family-interacting protein 1 NDFIP1 Tbio Non-IDG -1.24333 24.3 147
Transcription elongation factor A protein-like 8 TCEAL8 Tdark Non-IDG 1.04 0.09 44
Transcription elongation factor A protein-like 6 TCEAL6 Tdark Non-IDG 1.18 0.05 101
Transcription elongation factor A protein-like 3 TCEAL3 Tdark Non-IDG 0.00000 84