Development Level

Tbio 8 | 11,445
Tchem 2 | 1,598

IMPC Phenotype

increased grip strength 2 | 41
abnormal eating behavior 1 | 1
abnormal forced expiratory flo... 1 | 1
abnormal whole-body plethysmog... 1 | 4
altered righting response 1 | 1
decreased body temperature 1 | 2
decreased body weight 1 | 161
decreased tidal volume 1 | 1
increased blood urea nitrogen ... 1 | 48
increased circulating iron lev... 1 | 30
increased leukocyte cell numbe... 1 | 47
increased lymphocyte cell numb... 1 | 32
increased monocyte cell number 1 | 63
preweaning lethality, complete... 1 | 979
preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 8 | 11,493
medulloblastoma, large-cell 7 | 6,241
ovarian cancer 7 | 8,520
Breast cancer 6 | 3,578
Cancer 6 | 2,499
ependymoma 6 | 4,679
lung adenocarcinoma 6 | 2,716
lung cancer 6 | 4,740
psoriasis 6 | 6,694
Dull intelligence 5 | 645
Intellectual disability 5 | 1,016
Low intelligence 5 | 645
Mental Retardation 5 | 645
Mental deficiency 5 | 645
Multiple myeloma 5 | 1,332
Poor school performance 5 | 645
Short stature 5 | 531
group 3 medulloblastoma 5 | 4,104
osteosarcoma 5 | 7,950
pancreatic cancer 5 | 2,398
primitive neuroectodermal tumor 5 | 3,035
Cognitive delay 4 | 608
Global developmental delay 4 | 608
Mental and motor retardation 4 | 608
Nystagmus 4 | 317
acute quadriplegic myopathy 4 | 1,158
colon cancer 4 | 1,478
dermatomyositis 4 | 966
diabetes mellitus 4 | 1,728
glioblastoma 4 | 5,792
invasive ductal carcinoma 4 | 2,951
oligodendroglioma 4 | 2,850
Acquired scoliosis 3 | 281
Astrocytoma, Pilocytic 3 | 3,081
Autosomal recessive predisposition 3 | 1,442
Broad flat nasal bridge 3 | 236
Cryptorchidism 3 | 296
Curvature of spine 3 | 282
Dental abnormalities 3 | 60
Epilepsy 3 | 792
Fetal Growth Retardation 3 | 189
Infant, Small for Gestational Age 3 | 176
Intrauterine retardation 3 | 176
Long eyelashes 3 | 37
Macrostomia 3 | 72
Muscle hypotonia 3 | 571
Nasal bridge wide 3 | 236
Seizures 3 | 596
Small head 3 | 374
Strabismus 3 | 270
Tooth Abnormalities 3 | 69
adult high grade glioma 3 | 3,801
astrocytoma 3 | 1,146
atypical teratoid / rhabdoid tumor 3 | 5,112
ductal carcinoma in situ 3 | 1,745
group 4 medulloblastoma 3 | 1,855
juvenile dermatomyositis 3 | 1,187
malignant mesothelioma 3 | 3,232
primary pancreatic ductal adenocarcinoma 3 | 1,109
subependymal giant cell astrocytoma 3 | 2,287
Abnormality of cardiovascular system morphology 2 | 23
Bushy eyebrows 2 | 49
Cataract 2 | 297
Cerebellar Ataxia 2 | 304
Cerebellar hypoplasia and atrophy 2 | 41
Choreatic disease 2 | 52
Coarse facial features 2 | 108
Coffin-Siris syndrome 2 | 17
Concave bridge of nose 2 | 195
Congenital deafness 2 | 185
Congenital hypoplasia of penis 2 | 176
Dandy-Walker Syndrome 2 | 39
Deafness 2 | 198
Depressed nasal bridge 2 | 195
Depressed nasal ridge 2 | 51
Depressed nasal root/bridge 2 | 195
Feeding difficulties in infancy 2 | 175
Full lower lip 2 | 64
Generalized hirsutism 2 | 36
Hearing Loss, Partial 2 | 185
Joint hyperflexibility 2 | 78
Kyphoscoliosis deformity of spine 2 | 60
Lens Opacities 2 | 231
Mild Mental Retardation 2 | 70
Obesity 2 | 678
Patella aplasia-hypoplasia 2 | 12
Prominent lower lip 2 | 64
Recurrent respiratory infections 2 | 141
Short distal phalanges 2 | 50
Thickened facial skin with coarse facial features 2 | 108
Waldenstrons macroglobulinemia 2 | 765
acute myeloid leukemia 2 | 783
astrocytic glioma 2 | 2,597
atypical teratoid/rhabdoid tumor 2 | 357
hearing impairment 2 | 199
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
mucosa-associated lymphoid tissue lymphoma 2 | 484
non-small cell lung cancer 2 | 2,890
pituitary cancer 2 | 1,972
spina bifida 2 | 1,074

Tissue

Blood and immune system 10 | 16,909
Cardiovascular System 10 | 15,192
Digestive Tract 10 | 17,369
Endocrine System 10 | 18,159
Female tissues 10 | 17,400
Liver and Pancreas 10 | 16,750
Male tissues 10 | 17,142
Nervous System 10 | 16,725
Respiratory system 10 | 16,393
Skin and soft tissues 10 | 17,230
Urinary Tract 10 | 16,678

Target Family

Non-IDG 7 | 12,091
Enzyme 2 | 4,145
Epigenetic 1 | 242

GO Function

Tat protein binding 10 | 10
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
RNA polymerase II subunit A C-terminal domain phosphatase CTDP1 Tbio Enzyme -1.88697 80.7 113
Gamma-aminobutyric acid receptor-associated protein-like 1 GABARAPL1 Tbio Non-IDG -2.39692 232.7 211
MyoD family inhibitor domain-containing protein MDFIC Tbio Non-IDG -2.90969 749.0 122
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 SMARCB1 Tbio Non-IDG -2.77635 619.8 379
Transcription activator BRG1 SMARCA4 Tchem Epigenetic -2.86389 713.1 332
Nucleophosmin NPM1 Tbio Non-IDG -3.12496 1315.8 912
DnaJ homolog subfamily A member 1 DNAJA1 Tchem Non-IDG -1.81232 65.4 189
Actin, cytoplasmic 1 ACTB Tbio Non-IDG -3.52930 2830.7 1251
Delta-like protein 1 DLL1 Tbio Non-IDG -3.09375 1190.2 344
E3 ubiquitin-protein ligase TRIM32 TRIM32 Tbio Enzyme -1.92209 86.4 142