Development Level

Tbio 7 | 11,445
Tchem 1 | 1,598

IMPC Phenotype

decreased body weight 1 | 161

Disease

Carcinoma 8 | 11,493
ovarian cancer 6 | 8,520
osteosarcoma 5 | 7,950
Adenocarcinoma of lung 4 | 142
Cancer 4 | 2,499
lung cancer 4 | 4,740
medulloblastoma, large-cell 4 | 6,241
Neoplasm Metastasis 3 | 168
diabetes mellitus 3 | 1,728
glioblastoma 3 | 5,792
group 3 medulloblastoma 3 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
Adenocarcinoma of lung (disorder) 2 | 60
Arsenic Poisoning 2 | 62
Autosomal recessive predisposition 2 | 1,442
Breast Neoplasms 2 | 445
Breast cancer 2 | 3,578
Cataract 2 | 297
Cockayne syndrome 2 | 60
Cognitive delay 2 | 608
Disease Models, Animal 2 | 155
Electroencephalogram abnormal 2 | 101
Enophthalmos 2 | 75
Genetic Predisposition to Disease 2 | 27
Global developmental delay 2 | 608
Hypertensive disease 2 | 292
Hypogonadism 2 | 173
Lens Opacities 2 | 231
Low Vision 2 | 174
Mammary Neoplasms 2 | 425
Melanoma 2 | 711
Mental and motor retardation 2 | 608
Multiple myeloma 2 | 1,332
Neoplasms 2 | 63
Neoplasms, Germ Cell and Embryonal 2 | 15
Peripheral Nervous System Diseases 2 | 52
Peripheral Neuropathy 2 | 134
Photosensitivity of skin 2 | 51
Sensorineural Hearing Loss (disorder) 2 | 284
Short stature 2 | 531
Small head 2 | 374
Stomach Neoplasms 2 | 300
Sunken eyes 2 | 63
Testicular Neoplasms 2 | 6
Visual Impairment 2 | 174
XFE progeroid syndrome 2 | 3
Xeroderma pigmentosum 2 | 43
acute quadriplegic myopathy 2 | 1,158
atypical teratoid / rhabdoid tumor 2 | 5,112
colon cancer 2 | 1,478
invasive ductal carcinoma 2 | 2,951
malignant mesothelioma 2 | 3,232
non primary Sjogren syndrome sicca 2 | 891
pancreatic cancer 2 | 2,398
pancreatic carcinoma 2 | 562
pediatric high grade glioma 2 | 1,064
primitive neuroectodermal tumor 2 | 3,035
psoriasis 2 | 6,694
Abnormal nasal morphology 1 | 16
Abnormally small eyeball on both sides 1 | 5
Arthritis, Experimental 1 | 39
Atrophic condition of skin 1 | 25
Basal cell nevi 1 | 23
Bilateral nanophthalmos 1 | 5
Bone marrow hypocellularity 1 | 20
Cerebral calcification 1 | 43
Chromosome Breakage 1 | 36
Conduct disorder 1 | 33
Convex nasal bridge 1 | 57
Defective enamel matrix 1 | 35
Dental Enamel Hypoplasia 1 | 43
Dental abnormalities 1 | 60
Dyslipidemias 1 | 27
Dysplasia of tooth enamel 1 | 35
Erythema 1 | 58
Everted lower lip vermilion 1 | 54
Hepatitis 1 | 67
Hyperkeratosis 1 | 50
Hyperpigmented macules 1 | 42
Hypertrophy 1 | 17
Increased chromosomal breakage 1 | 27
Irregular hyperpigmentation 1 | 33
Kyphoscoliosis deformity of spine 1 | 60
Lung Injury 1 | 20
Microphthalmia, bilateral 1 | 5
Mild Mental Retardation 1 | 70
Neoplasms, Experimental 1 | 40
Papilloma 1 | 44
Poikiloderma 1 | 14
Precociously senile appearance 1 | 18
Progressive mental retardation 1 | 37
Prominent nasal bridge 1 | 57
Protruding lower lip 1 | 54
Radial aplasia/hypoplasia 1 | 29
Thin dental enamel 1 | 35
Thumb aplasia 1 | 16
Tracheoesophageal Fistula 1 | 36
Xeroderma pigmentosum group F 1 | 22
alcohol use disorder 1 | 12
hypopigmented skin patch 1 | 59

Tissue

Blood and immune system 8 | 16,909
Cardiovascular System 8 | 15,192
Digestive Tract 8 | 17,369
Endocrine System 8 | 18,159
Female tissues 8 | 17,400
Liver and Pancreas 8 | 16,750
Male tissues 8 | 17,142
Nervous System 8 | 16,725
Respiratory system 8 | 16,393
Skin and soft tissues 8 | 17,230
Urinary Tract 8 | 16,678

Target Family

Non-IDG 5 | 12,091
Enzyme 2 | 4,145
Transcription Factor 1 | 1,400

GO Function

TFIID-class transcription fact... 8 | 8
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Nucleolar protein 58 NOP58 Tbio Non-IDG -1.46442 30.0 85
Box C/D snoRNA protein 1 ZNHIT6 Tbio Non-IDG 0.48 0.74 87
Aryl hydrocarbon receptor AHR Tchem Transcription Factor 0.00000 773
rRNA 2'-O-methyltransferase fibrillarin FBL Tbio Enzyme -3.27338 1797.8 248
DNA repair endonuclease XPF ERCC4 Tbio Enzyme -1.91482 69.2 286
RuvB-like 2 RUVBL2 Tbio Non-IDG -1.95930 93.1 233
RuvB-like 1 RUVBL1 Tbio Non-IDG -1.88763 79.0 257
DNA excision repair protein ERCC-1 ERCC1 Tbio Non-IDG -3.02686 1089.9 878