Development Level

Tbio 7 | 11,445
Tchem 1 | 1,598
Tclin 1 | 613

IMPC Phenotype

preweaning lethality, complete... 2 | 979
abnormal behavior 1 | 298
abnormal embryo size 1 | 220
decreased lean body mass 1 | 135

Disease

Carcinoma 7 | 11,493
medulloblastoma, large-cell 6 | 6,241
osteosarcoma 6 | 7,950
atypical teratoid / rhabdoid tumor 5 | 5,112
glioblastoma 5 | 5,792
Cancer 4 | 2,499
ovarian cancer 4 | 8,520
primitive neuroectodermal tumor 4 | 3,035
ulcerative colitis 4 | 1,819
Pick disease 3 | 1,894
Rheumatoid arthritis 3 | 1,191
Schizophrenia 3 | 1,160
group 3 medulloblastoma 3 | 4,104
invasive ductal carcinoma 3 | 2,951
lung cancer 3 | 4,740
Breast cancer 2 | 3,578
Inflammatory bowel disease 2 | 151
Intellectual disability 2 | 1,016
Multiple Sclerosis 2 | 540
Multiple myeloma 2 | 1,332
Obesity 2 | 678
Oligomenorrhea 2 | 16
Prostatic Neoplasms 2 | 495
Stevens-Johnson syndrome 2 | 92
ductal carcinoma in situ 2 | 1,745
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
medulloblastoma 2 | 720
psoriasis 2 | 6,694
tuberculosis and treatment for 6 months 2 | 409
Acquired thrombocytopenia 1 | 8
Allergic asthma 1 | 6
Allergic bronchopulmonary aspergillosis 1 | 4
Allergic conjunctivitis 1 | 22
Anterior uveitis 1 | 3
Aphthous ulcer of mouth 1 | 7
Aspiration pneumonitis 1 | 6
Asthma management 1 | 19
Autoimmune disease 1 | 5
Autoimmune hemolytic anemia 1 | 31
Blepharoconjunctivitis 1 | 5
Branch retinal vein occlusion with macular edema 1 | 4
Bursitis 1 | 10
COPD Associated with Chronic Bronchitis 1 | 11
Candidiasis of skin 1 | 6
Central retinal vein occlusion with macular edema 1 | 4
Chloasma 1 | 6
Choroiditis 1 | 5
Chronic lymphoid leukemia, disease 1 | 13
Chronic ulcerative proctitis 1 | 7
Congenital hypoplastic anemia 1 | 8
Diabetic cataract 1 | 7
Disorder of skin 1 | 5
Eczema 1 | 45
Edema of larynx 1 | 5
Extrinsic allergic alveolitis 1 | 6
Fibrosis of lung 1 | 4
Gingival Disorders 1 | 3
Herpes zoster keratitis 1 | 5
Humoral hypercalcemia of malignancy 1 | 6
Hypoaldosteronism 1 | 12
Ileal neoplasm 1 | 3
Increased circulating cortisol level 1 | 7
Infection by larvae of Trichinella spiralis 1 | 3
Infective blepharitis 1 | 5
Inflammatory dermatosis 1 | 3
Iritis 1 | 8
Itching of ear 1 | 3
Lung Diseases, Obstructive 1 | 4
Mastoidectomy Cavity Infections 1 | 3
Meibomianitis 1 | 4
Miles-Carpenter syndrome 1 | 4
Miliary tuberculosis 1 | 6
Mineralocorticoid insufficiency 1 | 12
Minor Bacterial Skin Infections 1 | 3
Neoplasms, Second Primary 1 | 6
Non-allergic asthma 1 | 5
Ocular rosacea 1 | 4
Perennial allergic rhinitis 1 | 2
Pityriasis simplex 1 | 6
Plaque psoriasis 1 | 17
Polymyalgia rheumatica 1 | 10
Post traumatic osteoarthritis 1 | 5
Post-Op Ocular Inflammation 1 | 9
Postoperative Ocular Pain 1 | 5
Pregnancy with abortive outcome 1 | 8
Prevention of Transplant Rejection 1 | 6
Progressive Diffuse Large B-Cell Lymphoma 1 | 4
Recurrent herpes simplex labialis 1 | 3
Rosacea 1 | 25
Scalp psoriasis 1 | 6
Seasonal allergic rhinitis 1 | 9
Severe Ocular Inflammation 1 | 4
Superficial Ocular Infection 1 | 6
Systemic Dermatomyositis 1 | 5
Tendinitis 1 | 14
Tenosynovitis 1 | 14
Tinea cruris 1 | 12
Toxic diffuse goiter 1 | 2
Transplanted organ rejection 1 | 10
Xeroderma pigmentosum group C 1 | 5

Tissue

Blood and immune system 9 | 16,909
Cardiovascular System 9 | 15,192
Digestive Tract 9 | 17,369
Endocrine System 9 | 18,159
Female tissues 9 | 17,400
Liver and Pancreas 9 | 16,750
Male tissues 9 | 17,142
Nervous System 9 | 16,725
Respiratory system 9 | 16,393
Skin and soft tissues 9 | 17,230
Urinary Tract 9 | 16,678

Target Family

Non-IDG 4 | 12,091
Enzyme 3 | 4,145
Epigenetic 1 | 242
Nuclear Receptor 1 | 48

GO Function

SUMO binding 9 | 9
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
G/T mismatch-specific thymine DNA glycosylase TDG Tbio Enzyme -2.46252 297.6 225
SUMO-specific isopeptidase USPL1 USPL1 Tbio Enzyme -0.37414 2.22 15
E3 SUMO-protein ligase CBX4 CBX4 Tchem Epigenetic -1.32793 21.9 353
Protein PML PML Tbio Non-IDG -2.63785 373.8 470
E3 ubiquitin-protein ligase HERC2 HERC2 Tbio Enzyme -1.25001 18.4 38
Toll-interacting protein TOLLIP Tbio Non-IDG -1.87544 81.6 423
Glucocorticoid receptor NR3C1 Tclin Nuclear Receptor -3.44829 2272.9 857
SUMO-activating enzyme subunit 2 UBA2 Tbio Non-IDG -1.47530 27.8 259
Death domain-associated protein 6 DAXX Tbio Non-IDG -2.33534 233.0 762