Development Level

Tbio 38 | 11,445
Tdark 7 | 6,588
Tchem 1 | 1,598

IMPC Phenotype

preweaning lethality, complete... 10 | 979
preweaning lethality, incomple... 3 | 499
decreased circulating insulin ... 2 | 76
decreased total body fat amoun... 2 | 207
embryonic lethality prior to o... 2 | 239
embryonic lethality prior to t... 2 | 278
abnormal behavior 1 | 298
abnormal cranium morphology 1 | 36
abnormal epididymis morphology 1 | 42
abnormal gait 1 | 69
abnormal lens morphology 1 | 81
abnormal liver morphology 1 | 17
abnormal motor capabilities-co... 1 | 5
abnormal optic disc morphology 1 | 10
abnormal snout morphology 1 | 23
abnormal stomach morphology 1 | 10
abnormal testis morphology 1 | 43
abnormal thymus morphology 1 | 7
abnormal tooth morphology 1 | 24
convulsive seizures 1 | 13
decreased blood urea nitrogen ... 1 | 51
decreased circulating chloride... 1 | 30
decreased circulating creatini... 1 | 39
decreased circulating glucose ... 1 | 126
decreased circulating lactate ... 1 | 3
decreased circulating serum al... 1 | 82
decreased circulating triglyce... 1 | 79
decreased fasted circulating g... 1 | 65
decreased large unstained cell... 1 | 11
decreased total retina thickne... 1 | 17
enlarged epididymis 1 | 31
hemorrhage 1 | 23
impaired glucose tolerance 1 | 75
increased circulating iron lev... 1 | 30
increased erythrocyte cell num... 1 | 39
increased fasted circulating g... 1 | 76
increased grip strength 1 | 41
increased heart rate 1 | 23
increased neutrophil cell numb... 1 | 46
increased total body fat amoun... 1 | 134
limb grasping 1 | 41
short tibia 1 | 97
small thymus 1 | 16

Disease

ovarian cancer 28 | 8,520
Carcinoma 25 | 11,493
medulloblastoma, large-cell 22 | 6,241
osteosarcoma 22 | 7,950
glioblastoma 19 | 5,792
psoriasis 15 | 6,694
atypical teratoid / rhabdoid tumor 13 | 5,112
ependymoma 13 | 4,679
Astrocytoma, Pilocytic 12 | 3,081
Pick disease 11 | 1,894
group 3 medulloblastoma 11 | 4,104
lung cancer 11 | 4,740
adult high grade glioma 10 | 3,801
intraductal papillary-mucinous adenoma (IPMA) 10 | 2,955
invasive ductal carcinoma 10 | 2,951
intraductal papillary-mucinous neoplasm (IPMN) 9 | 3,291
malignant mesothelioma 9 | 3,232
non-small cell lung cancer 9 | 2,890
Hypomyelinating leukodystrophy 6 8 | 26
Tetanus 8 | 68
lung adenocarcinoma 8 | 2,716
oligodendroglioma 8 | 2,850
Schizophrenia 7 | 1,160
lung carcinoma 7 | 2,843
Kidney cancer 6 | 2,613
astrocytic glioma 6 | 2,597
dermatomyositis 6 | 966
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,989
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,962
primitive neuroectodermal tumor 6 | 3,035
subependymal giant cell astrocytoma 6 | 2,287
tuberculosis 6 | 2,010
Multiple myeloma 5 | 1,332
Vici syndrome 5 | 14
astrocytoma 5 | 1,146
cystic fibrosis 5 | 1,696
ductal carcinoma in situ 5 | 1,745
group 4 medulloblastoma 5 | 1,855
Alzheimer's disease 4 | 658
Autosomal recessive predisposition 4 | 1,442
Bipolar Disorder 4 | 666
Breast cancer 4 | 3,578
Epilepsy 4 | 792
Hermansky-Pudlak syndrome 4 | 42
Muscle hypotonia 4 | 571
active Crohn's disease 4 | 922
active ulcerative colitis 4 | 764
diabetes mellitus 4 | 1,728
pancreatic cancer 4 | 2,398
spina bifida 4 | 1,074
Botulism 3 | 24
Diarrhea 3 | 253
Gaucher disease type 1 3 | 180
Parkinson's disease 3 | 392
Rheumatoid arthritis 3 | 1,191
Short stature 3 | 531
Waldenstrons macroglobulinemia 3 | 765
acute quadriplegic myopathy 3 | 1,158
adrenocortical carcinoma 3 | 1,428
colon cancer 3 | 1,478
gastric cancer 3 | 459
interstitial cystitis 3 | 2,312
mucosa-associated lymphoid tissue lymphoma 3 | 484
pancreatic carcinoma 3 | 562
pediatric high grade glioma 3 | 1,064
pituitary cancer 3 | 1,972
progressive supranuclear palsy 3 | 676
tuberculosis and treatment for 6 months 3 | 409
ulcerative colitis 3 | 1,819
Acquired scoliosis 2 | 281
Anemia 2 | 365
Attention deficit hyperactivity disorder 2 | 278
Cataract 8 multiple types 2 | 33
Colitis 2 | 54
Congenital Epicanthus 2 | 177
Curvature of spine 2 | 282
Endometriosis 2 | 540
Exophthalmos 2 | 112
Heart disease 2 | 306
Immunologic Deficiency Syndromes 2 | 113
Kidney Failure 2 | 111
Long philtrum 2 | 137
MAJOR AFFECTIVE DISORDER 2 2 | 22
Major Depressive Disorder 2 | 301
Male infertility 2 | 206
Melanoma 2 | 711
Multiple Sclerosis 2 | 540
Myoclonic Epilepsies, Progressive 2 | 44
Neurodegenerative disease 2 | 414
Primary biliary cirrhosis 2 | 51
Prominent eyes 2 | 96
Prominent globes 2 | 96
Protruding eyes 2 | 96
Tremor 2 | 113
Type 2 diabetes mellitus 2 | 272
Unipolar Depression 2 | 250
acute myeloid leukemia 2 | 783
aldosterone-producing adenoma 2 | 665
facioscapulohumeral dystrophy 2 | 288
gastric carcinoma 2 | 807

Tissue

Blood and immune system 46 | 16,909
Digestive Tract 46 | 17,369
Endocrine System 46 | 18,159
Female tissues 46 | 17,400
Liver and Pancreas 46 | 16,750
Male tissues 46 | 17,142
Nervous System 46 | 16,725
Respiratory system 46 | 16,393
Skin and soft tissues 46 | 17,230
Urinary Tract 46 | 16,678
Cardiovascular System 44 | 15,192

Target Family

Non-IDG 43 | 12,091
Enzyme 2 | 4,145
Kinase 1 | 634

GO Function

SNARE binding 46 | 46
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Alpha-soluble NSF attachment protein NAPA Tbio Non-IDG -1.91664 86.4 148
Exocyst complex component 3-like protein EXOC3L1 Tdark Non-IDG 0.10 1.30 62
Calpain-10 CAPN10 Tbio Non-IDG -2.27096 197.8 112
Ankyrin repeat domain-containing protein 27 ANKRD27 Tbio Non-IDG -1.12548 14.6 65
Golgi SNAP receptor complex member 1 GOSR1 Tbio Non-IDG -1.32565 21.7 128
Vesicle-trafficking protein SEC22a SEC22A Tdark Non-IDG 0.33 0.44 19
SNARE-associated protein Snapin SNAPIN Tbio Non-IDG -1.65821 50.9 69
Exocyst complex component 3-like protein 4 EXOC3L4 Tdark Non-IDG 0.48 0.25 7
Vesicle-fusing ATPase NSF Tbio Enzyme -2.93271 688.8 206
Syntaxin-2 STX2 Tbio Non-IDG -2.93775 902.6 197