Development Level

Tbio 29 | 10,625
Tdark 7 | 7,003
Tchem 1 | 1,890

IMPC Term

decreased circulating insulin ... 3 | 75
increased lean body mass 3 | 107
preweaning lethality, complete... 3 | 633
abnormal behavior 2 | 226
decreased total body fat amoun... 2 | 186
increased bone mineral content 2 | 92
abnormal QRS complex 1 | 25
abnormal epididymis morphology 1 | 31
abnormal gait 1 | 51
abnormal sleep behavior 1 | 63
abnormal testis morphology 1 | 30
absent vibrissae 1 | 14
decreased circulating chloride... 1 | 32
decreased circulating glucose ... 1 | 121
decreased circulating triglyce... 1 | 83
decreased effector memory CD4-... 1 | 6
decreased fasted circulating g... 1 | 49
decreased gamma-delta T cell n... 1 | 18
decreased granulocyte number 1 | 8
decreased late germinal center... 1 | 2
decreased lean body mass 1 | 195
decreased lumbar vertebrae num... 1 | 62
decreased monocyte cell number 1 | 28
decreased myeloid cell number ... 1 | 1
decreased pre-pro B cell numbe... 1 | 2
decreased pro-B cell number 1 | 2
decreased rib number 1 | 59
embryonic lethality prior to o... 1 | 148
embryonic lethality prior to t... 1 | 187
enlarged epididymis 1 | 27
immune system phenotype 1 | 17
increased B cell number 1 | 23
increased T cell number 1 | 15
increased body weight 1 | 42
increased bone mineral density 1 | 52
increased early germinal cente... 1 | 2
increased exploration in new e... 1 | 56
increased grip strength 1 | 83
increased immature B cell numb... 1 | 1
increased mature B cell number 1 | 12
increased or absent threshold ... 1 | 128
increased pre-B cell number 1 | 1
increased sacral vertebrae num... 1 | 62
increased total body fat amoun... 1 | 57
limb grasping 1 | 35
shortened RR interval 1 | 19

Disease

ovarian cancer 24 | 8,492
medulloblastoma, large-cell 20 | 6,234
osteosarcoma 20 | 7,933
psoriasis 16 | 6,685
glioblastoma 14 | 5,572
atypical teratoid / rhabdoid tumor 10 | 4,369
group 4 medulloblastoma 10 | 1,875
Tetanus 9 | 66
lung cancer 9 | 4,473
malignant mesothelioma 9 | 3,163
pilocytic astrocytoma 9 | 3,086
Pick disease 8 | 1,893
astrocytoma 7 | 1,493
ependymoma 7 | 2,514
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,289
invasive ductal carcinoma 7 | 2,950
oligodendroglioma 7 | 2,849
group 3 medulloblastoma 6 | 2,254
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,956
lung adenocarcinoma 6 | 2,714
non-small cell lung cancer 6 | 2,798
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,795
pediatric high grade glioma 6 | 2,712
tuberculosis 6 | 1,563
Multiple myeloma 5 | 1,328
Vici syndrome 5 | 16
cystic fibrosis 5 | 1,670
dermatomyositis 5 | 967
ductal carcinoma in situ 5 | 1,745
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,988
lung carcinoma 5 | 2,844
Alzheimer's disease 4 | 644
primitive neuroectodermal tumor 4 | 3,031
subependymal giant cell astrocytoma 4 | 2,287
tuberculosis and treatment for 6 months 4 | 686
Botulism 3 | 20
Diarrhea 3 | 155
Gaucher disease type 1 3 | 171
acute quadriplegic myopathy 3 | 1,157
adrenocortical carcinoma 3 | 1,427
astrocytic glioma 3 | 2,241
atypical teratoid/rhabdoid tumor 3 | 1,095
colon cancer 3 | 1,475
gastric cancer 3 | 436
juvenile dermatomyositis 3 | 1,189
non primary Sjogren syndrome sicca 3 | 840
pancreatic cancer 3 | 2,300
pancreatic carcinoma 3 | 567
posterior fossa group B ependymoma 3 | 1,530
progressive supranuclear palsy 3 | 674
spina bifida 3 | 1,064
ulcerative colitis 3 | 2,087
Anemia 2 | 252
Batten disease 2 | 15
Colitis 2 | 46
Down syndrome 2 | 548
Epilepsy 2 | 346
Gastroenteritis 2 | 46
Heart disease 2 | 279
Hermansky-Pudlak syndrome 2 | 43
IGA Glomerulonephritis 2 | 454
Kidney failure 2 | 41
Rheumatoid Arthritis 2 | 1,171
Schizophrenia 2 | 503
Waldenstrons macroglobulinemia 2 | 765
active Crohn's disease 2 | 918
adult high grade glioma 2 | 2,148
aldosterone-producing adenoma 2 | 664
axial spondyloarthropathy 2 | 28
breast carcinoma 2 | 1,614
interstitial cystitis 2 | 2,299
medulloblastoma 2 | 1,524
nasopharyngeal carcinoma 2 | 1,056
pituitary cancer 2 | 1,972
posterior fossa group A ependymoma 2 | 1,511
Animal Mammary Neoplasms 1 | 136
Bipolar Disorder 1 | 266
Blood pressure finding 1 | 56
Brain disease 1 | 84
COPD 1 | 116
Ceroid lipofuscinosis, neuronal, 6 1 | 7
Chediak-Higashi syndrome 1 | 24
Chromosome 17q11.2 deletion syndrome, 1.4Mb 1 | 14
Colorectal Cancer 1 | 62
Colorectal Neoplasms 1 | 217
Depressive disorder 1 | 48
Diabetes Mellitus, Experimental 1 | 106
Disease of anatomical entity 1 | 25
Hemolytic anemia 1 | 70
Hyperphosphatemia 1 | 32
Hypohidrosis 1 | 13
MEDNIK syndrome 1 | 8
Mammary Neoplasms, Experimental 1 | 150
Melanoma 1 | 261
Pseudohypoaldosteronism 1 | 22
Systemic arterial pressure 1 | 56
Thrombocytopenia 1 | 105
Visual epilepsy 1 | 4
Vitiligo 1 | 71
chorea-acanthocytosis 1 | 11

Tissue

Blood and immune system 37 | 17,995
Cardiovascular System 37 | 17,958
Digestive Tract 37 | 18,473
Endocrine System 37 | 18,512
Female tissues 37 | 18,647
Liver and Pancreas 37 | 18,136
Male tissues 37 | 17,969
Nervous System 37 | 18,561
Respiratory system 37 | 17,484
Urinary Tract 37 | 18,444
Skin and soft tissues 36 | 18,115

Target Family

Non-IDG 37 | 11,969

GO Function

SNAP receptor activity 37 | 37
metal ion binding 1,917 | 1,917
ATP binding 1,467 | 1,467
DNA binding 1,432 | 1,432
zinc ion binding 1,155 | 1,155
poly(A) RNA binding 1,107 | 1,107
transcription factor activity,... 853 | 853
calcium ion binding 695 | 695
G-protein coupled receptor act... 661 | 661
protein homodimerization activ... 569 | 569
RNA binding 445 | 445
olfactory receptor activity 424 | 424
sequence-specific DNA binding 398 | 398
GTP binding 374 | 374
chromatin binding 372 | 372
protein serine/threonine kinas... 336 | 336
RNA polymerase II core promote... 332 | 332
identical protein binding 311 | 311
nucleotide binding 311 | 311
receptor binding 303 | 303
protein kinase binding 289 | 289
enzyme binding 286 | 286
cadherin binding involved in c... 277 | 277
GTPase activator activity 273 | 273
ubiquitin protein ligase bindi... 258 | 258
ubiquitin-protein transferase ... 253 | 253
serine-type endopeptidase acti... 246 | 246
transcription coactivator acti... 241 | 241
transcription factor binding 240 | 240
structural molecule activity 232 | 232
GTPase activity 231 | 231
transcriptional activator acti... 230 | 230
ligase activity 227 | 227
protein heterodimerization act... 227 | 227
structural constituent of ribo... 212 | 212
transcription regulatory regio... 202 | 202
transmembrane signaling recept... 201 | 201
RNA polymerase II regulatory r... 200 | 200
receptor activity 200 | 200
transcription corepressor acti... 198 | 198
magnesium ion binding 197 | 197
signal transducer activity 196 | 196
nucleic acid binding 184 | 184
protein kinase activity 183 | 183
carbohydrate binding 180 | 180
ubiquitin protein ligase activ... 173 | 173
RNA polymerase II transcriptio... 162 | 162
heparin binding 160 | 160
iron ion binding 141 | 141
lipid binding 136 | 136
transporter activity 136 | 136
actin binding 133 | 133
ATPase activity 132 | 132
protein C-terminus binding 129 | 129
heme binding 127 | 127
microtubule binding 123 | 123
protein tyrosine kinase activi... 119 | 119
cytokine activity 118 | 118
Ras guanyl-nucleotide exchange... 113 | 113
mRNA binding 112 | 112
metalloendopeptidase activity 112 | 112
transcriptional repressor acti... 110 | 110
structural constituent of cyto... 108 | 108
Rab GTPase binding 105 | 105
antigen binding 104 | 104
protein domain specific bindin... 102 | 102
peptide antigen binding 101 | 101
guanyl-nucleotide exchange fac... 98 | 98
protein complex binding 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 92 | 92
oxidoreductase activity 91 | 91
transcriptional activator acti... 91 | 91
actin filament binding 89 | 89
hydrolase activity 89 | 89
ion channel binding 89 | 89
protein tyrosine phosphatase a... 88 | 88
electron carrier activity 87 | 87
protease binding 87 | 87
histone binding 86 | 86
integrin binding 83 | 83
growth factor activity 82 | 82
phospholipid binding 82 | 82
single-stranded DNA binding 81 | 81
unfolded protein binding 77 | 77
kinase activity 75 | 75
thiol-dependent ubiquitin-spec... 75 | 75
phosphatidylinositol binding 74 | 74
calmodulin binding 73 | 73
histone deacetylase binding 73 | 73
Rho guanyl-nucleotide exchange... 72 | 72
drug binding 71 | 71
double-stranded DNA binding 70 | 70
peptidase activity 70 | 70
protein N-terminus binding 70 | 70
virus receptor activity 68 | 68
beta-catenin binding 67 | 67
microtubule motor activity 67 | 67
protein transporter activity 67 | 67
calcium channel activity 66 | 66
ubiquitin binding 66 | 66

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Syntaxin-4 STX4 Tbio Non-IDG -1.93051 79.1 192
Vesicle-trafficking protein SEC22c SEC22C Tdark Non-IDG 0.06 0.49 29
Vesicle-associated membrane protein 8 VAMP8 Tbio Non-IDG -1.74294 59.3 105
Syntaxin-12 STX12 Tbio Non-IDG -1.08188 11.4 107
Synaptosomal-associated protein 29 SNAP29 Tbio Non-IDG -1.38923 23.6 114
Vesicle transport protein SEC20 BNIP1 Tbio Non-IDG -1.25063 18.7 257
Vesicle-associated membrane protein 7 VAMP7 Tbio Non-IDG -1.86113 81.7 133
Syntaxin-1B STX1B Tbio Non-IDG -1.73730 52.6 27
Syntaxin-6 STX6 Tbio Non-IDG -1.75231 53.1 215
Synaptobrevin homolog YKT6 YKT6 Tbio Non-IDG -1.55865 36.8 21