Development Level

Tbio 32 | 10,625
Tchem 11 | 1,890
Tdark 3 | 7,003
Tclin 2 | 602

Collection

Eligible Kinase Proteins 1 | 134

IMPC Term

abnormal behavior 4 | 226
decreased circulating insulin ... 3 | 75
abnormal lens morphology 2 | 73
cardiovascular system phenotyp... 2 | 35
decreased total body fat amoun... 2 | 186
embryonic lethality prior to t... 2 | 187
increased bone mineral content 2 | 92
increased lean body mass 2 | 107
increased mean corpuscular hem... 2 | 93
increased startle reflex 2 | 38
persistence of hyaloid vascula... 2 | 22
preweaning lethality, complete... 2 | 633
abnormal coat/ hair morphology 1 | 18
abnormal embryo size 1 | 112
abnormal epididymis morphology 1 | 31
abnormal eye size 1 | 11
abnormal forebrain development 1 | 18
abnormal hindbrain development 1 | 24
abnormal midbrain development 1 | 22
abnormal nail morphology 1 | 7
abnormal neural tube closure 1 | 37
abnormal pericardium morpholog... 1 | 11
abnormal retina morphology 1 | 100
abnormal retinal blood vessel ... 1 | 18
abnormal retinal vasculature m... 1 | 15
abnormal testis morphology 1 | 30
absent pinna reflex 1 | 21
cataract 1 | 26
decreased CD4-positive, CD25-p... 1 | 24
decreased NK T cell number 1 | 28
decreased NK cell number 1 | 16
decreased blood urea nitrogen ... 1 | 31
decreased body length 1 | 108
decreased circulating amylase ... 1 | 24
decreased circulating iron lev... 1 | 25
decreased circulating triglyce... 1 | 83
decreased fasted circulating g... 1 | 49
decreased heart rate variabili... 1 | 11
decreased lumbar vertebrae num... 1 | 62
decreased mature B cell number 1 | 25
decreased mean corpuscular vol... 1 | 50
decreased startle reflex 1 | 48
decreased total retina thickne... 1 | 20
enlarged epididymis 1 | 27
hyperactivity 1 | 108
hypoactivity 1 | 89
impaired righting response 1 | 19
improved glucose tolerance 1 | 56
increased circulating alkaline... 1 | 119
increased circulating iron lev... 1 | 25
increased effector memory CD4-... 1 | 15
increased exploration in new e... 1 | 56
increased fasted circulating g... 1 | 68
increased grip strength 1 | 83
increased hemoglobin content 1 | 45
increased leukocyte cell numbe... 1 | 37
increased sacral vertebrae num... 1 | 62
polycystic kidney 1 | 9
preweaning lethality, incomple... 1 | 260
small testis 1 | 37
stereotypic behavior 1 | 3
trunk curl 1 | 15

Disease

ovarian cancer 25 | 8,484
glioblastoma 23 | 5,572
osteosarcoma 23 | 7,933
psoriasis 21 | 6,685
medulloblastoma, large-cell 19 | 6,234
atypical teratoid / rhabdoid tumor 16 | 4,369
lung cancer 16 | 4,466
malignant mesothelioma 14 | 3,162
Cancer 13 | 2,346
pilocytic astrocytoma 13 | 3,086
ependymoma 12 | 2,514
intraductal papillary-mucinous adenoma (IPMA) 12 | 2,956
pediatric high grade glioma 12 | 2,712
Carcinoma 11 | 2,147
intraductal papillary-mucinous neoplasm (IPMN) 11 | 3,289
oligodendroglioma 11 | 2,849
Pick disease 10 | 1,893
Rheumatoid Arthritis 10 | 1,160
lung adenocarcinoma 10 | 2,713
pancreatic cancer 10 | 2,300
subependymal giant cell astrocytoma 10 | 2,287
adult high grade glioma 9 | 2,148
lung carcinoma 9 | 2,844
non-small cell lung cancer 9 | 2,798
primitive neuroectodermal tumor 9 | 3,031
Alzheimer's disease 8 | 644
group 3 medulloblastoma 8 | 2,254
interstitial cystitis 8 | 2,299
intraductal papillary-mucinous carcinoma (IPMC) 8 | 2,988
invasive ductal carcinoma 8 | 2,950
ulcerative colitis 8 | 2,087
cutaneous lupus erythematosus 7 | 1,056
primary pancreatic ductal adenocarcinoma 7 | 1,271
astrocytoma 6 | 1,493
juvenile dermatomyositis 6 | 1,189
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,795
posterior fossa group A ependymoma 6 | 1,511
Autistic Disorder 5 | 320
Breast cancer 5 | 3,094
acute quadriplegic myopathy 5 | 1,157
astrocytic glioma 5 | 2,241
ductal carcinoma in situ 5 | 1,745
pituitary cancer 5 | 1,972
primary Sjogren syndrome 5 | 789
spina bifida 5 | 1,064
tuberculosis 5 | 1,557
Kidney disease 4 | 396
Parkinson's disease 4 | 364
atypical teratoid/rhabdoid tumor 4 | 1,095
breast carcinoma 4 | 1,614
dermatomyositis 4 | 933
diabetes mellitus 4 | 1,663
group 4 medulloblastoma 4 | 1,875
progressive supranuclear palsy 4 | 674
sonic hedgehog group medulloblastoma 4 | 1,482
Atherosclerosis 3 | 275
Diabetes Mellitus, Experimental 3 | 106
Down syndrome 3 | 548
Hypertensive disease 3 | 193
IGA Glomerulonephritis 3 | 454
Lung Neoplasms 3 | 171
Mammary Neoplasms 3 | 410
Multiple myeloma 3 | 1,327
Neurodegenerative disease 3 | 383
PARKINSON DISEASE, LATE-ONSET 3 | 18
Parkinson Disease 3 | 102
Prostatic Neoplasms 3 | 471
Toxic encephalopathy 3 | 131
Vascular disease 3 | 281
adrenocortical carcinoma 3 | 1,427
interstitial lung disease 3 | 291
medulloblastoma 3 | 1,524
non-inflammatory breast cancer 3 | 208
posterior fossa group B ependymoma 3 | 1,530
Atopic dermatitis 2 | 944
Bipolar Disorder 2 | 266
Bladder Neoplasm 2 | 109
Brain Ischemia 2 | 87
Cardiomyopathy 2 | 110
Dementia 2 | 129
Diabetes Mellitus, Non-Insulin-Dependent 2 | 157
Duchenne muscular dystrophy 2 | 602
Gaucher disease type 1 2 | 171
Heart disease 2 | 279
Hypertension 2 | 287
Multiple Sclerosis 2 | 498
Neuropathy 2 | 210
Osteoporosis 2 | 257
Peripheral Neuropathy 2 | 303
Schizophrenia 2 | 501
Vasculitis 2 | 64
X-linked cerebral adrenoleukodystrophy 2 | 115
active Crohn's disease 2 | 918
acute myeloid leukemia 2 | 780
colon cancer 2 | 1,475
esophageal adenocarcinoma 2 | 737
fibroadenoma 2 | 557
gastric carcinoma 2 | 832
non-small cell lung carcinoma 2 | 413
tuberculosis and treatment for 6 months 2 | 686

Tissue

Digestive Tract 48 | 18,473
Nervous System 48 | 18,561
Blood and immune system 47 | 17,995
Cardiovascular System 47 | 17,958
Endocrine System 47 | 18,512
Female tissues 47 | 18,647
Liver and Pancreas 47 | 18,136
Male tissues 47 | 17,969
Urinary Tract 47 | 18,444
Respiratory system 46 | 17,484
Skin and soft tissues 46 | 18,115

Target Family

Non-IDG 28 | 11,971
Enzyme 17 | 4,146
Kinase 2 | 634
GPCR 1 | 406

GO Function

SH3 domain binding 48 | 48
metal ion binding 1,917 | 1,917
ATP binding 1,467 | 1,467
DNA binding 1,432 | 1,432
zinc ion binding 1,155 | 1,155
poly(A) RNA binding 1,107 | 1,107
transcription factor activity,... 853 | 853
calcium ion binding 695 | 695
G-protein coupled receptor act... 661 | 661
protein homodimerization activ... 569 | 569
RNA binding 445 | 445
olfactory receptor activity 424 | 424
sequence-specific DNA binding 398 | 398
GTP binding 374 | 374
chromatin binding 372 | 372
protein serine/threonine kinas... 336 | 336
RNA polymerase II core promote... 332 | 332
identical protein binding 311 | 311
nucleotide binding 311 | 311
receptor binding 303 | 303
protein kinase binding 289 | 289
enzyme binding 286 | 286
cadherin binding involved in c... 277 | 277
GTPase activator activity 273 | 273
ubiquitin protein ligase bindi... 258 | 258
ubiquitin-protein transferase ... 253 | 253
serine-type endopeptidase acti... 246 | 246
transcription coactivator acti... 241 | 241
transcription factor binding 240 | 240
structural molecule activity 232 | 232
GTPase activity 231 | 231
transcriptional activator acti... 230 | 230
ligase activity 227 | 227
protein heterodimerization act... 227 | 227
structural constituent of ribo... 212 | 212
transcription regulatory regio... 202 | 202
transmembrane signaling recept... 201 | 201
RNA polymerase II regulatory r... 200 | 200
receptor activity 200 | 200
transcription corepressor acti... 198 | 198
magnesium ion binding 197 | 197
signal transducer activity 196 | 196
nucleic acid binding 184 | 184
protein kinase activity 183 | 183
carbohydrate binding 180 | 180
ubiquitin protein ligase activ... 173 | 173
RNA polymerase II transcriptio... 162 | 162
heparin binding 160 | 160
iron ion binding 141 | 141
lipid binding 136 | 136
transporter activity 136 | 136
actin binding 133 | 133
ATPase activity 132 | 132
protein C-terminus binding 129 | 129
heme binding 127 | 127
microtubule binding 123 | 123
protein tyrosine kinase activi... 119 | 119
cytokine activity 118 | 118
Ras guanyl-nucleotide exchange... 113 | 113
mRNA binding 112 | 112
metalloendopeptidase activity 112 | 112
transcriptional repressor acti... 110 | 110
structural constituent of cyto... 108 | 108
Rab GTPase binding 105 | 105
antigen binding 104 | 104
protein domain specific bindin... 102 | 102
peptide antigen binding 101 | 101
guanyl-nucleotide exchange fac... 98 | 98
protein complex binding 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 92 | 92
oxidoreductase activity 91 | 91
transcriptional activator acti... 91 | 91
actin filament binding 89 | 89
hydrolase activity 89 | 89
ion channel binding 89 | 89
protein tyrosine phosphatase a... 88 | 88
electron carrier activity 87 | 87
protease binding 87 | 87
histone binding 86 | 86
integrin binding 83 | 83
growth factor activity 82 | 82
phospholipid binding 82 | 82
single-stranded DNA binding 81 | 81
unfolded protein binding 77 | 77
kinase activity 75 | 75
thiol-dependent ubiquitin-spec... 75 | 75
phosphatidylinositol binding 74 | 74
calmodulin binding 73 | 73
histone deacetylase binding 73 | 73
Rho guanyl-nucleotide exchange... 72 | 72
drug binding 71 | 71
double-stranded DNA binding 70 | 70
peptidase activity 70 | 70
protein N-terminus binding 70 | 70
virus receptor activity 68 | 68
beta-catenin binding 67 | 67
microtubule motor activity 67 | 67
protein transporter activity 67 | 67
calcium channel activity 66 | 66
ubiquitin binding 66 | 66

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
LanC-like protein 1 LANCL1 Tbio Non-IDG -1.03436 11.5 49
Cytochrome b-245 light chain CYBA Tbio Non-IDG -2.56294 358.8 154
Growth factor receptor-bound protein 2 GRB2 Tchem Non-IDG -2.99303 933.5 424
Tyrosine-protein kinase ABL1 ABL1 Tclin Kinase -3.47805 3222.2 1533
Phospholipid scramblase 1 PLSCR1 Tbio Enzyme -1.74779 70.3 168
Dynamin-2 DNM2 Tchem Non-IDG -3.22299 1426.1 125
Protein crumbs homolog 3 CRB3 Tbio Non-IDG -1.16045 14.3 66
Neutrophil cytosol factor 1 NCF1 Tbio Non-IDG -2.74083 539.0 597
Disintegrin and metalloproteinase domain-containing protein 12 ADAM12 Tchem Enzyme -2.24301 200.8 285
Src kinase-associated phosphoprotein 1 SKAP1 Tbio Enzyme -1.25752 23.6 162