Development Level

Tbio 9 | 11,445
Tchem 2 | 1,598

IMPC Phenotype

abnormal embryo size 1 | 220
abnormal locomotor behavior 1 | 24
anophthalmia 1 | 33
dilated heart left ventricle 1 | 11
embryonic lethality prior to t... 1 | 278
impaired glucose tolerance 1 | 75
increased cardiac stroke volum... 1 | 1
increased prepulse inhibition 1 | 32
prenatal lethality prior to he... 1 | 87
preweaning lethality, complete... 1 | 979

Disease

Carcinoma 9 | 11,493
glioblastoma 8 | 5,792
ovarian cancer 8 | 8,520
lung cancer 7 | 4,740
adult high grade glioma 6 | 3,801
atypical teratoid / rhabdoid tumor 6 | 5,112
group 3 medulloblastoma 6 | 4,104
medulloblastoma, large-cell 6 | 6,241
Astrocytoma, Pilocytic 5 | 3,081
Cancer 5 | 2,499
ependymoma 5 | 4,679
osteosarcoma 4 | 7,950
pancreatic cancer 4 | 2,398
Breast cancer 3 | 3,578
Kidney cancer 3 | 2,613
adrenocortical carcinoma 3 | 1,428
invasive ductal carcinoma 3 | 2,951
oligodendroglioma 3 | 2,850
primary pancreatic ductal adenocarcinoma 3 | 1,109
primitive neuroectodermal tumor 3 | 3,035
Liver cancer 2 | 604
Melanoma 2 | 711
acute quadriplegic myopathy 2 | 1,158
astrocytic glioma 2 | 2,597
diabetes mellitus 2 | 1,728
interstitial cystitis 2 | 2,312
lung adenocarcinoma 2 | 2,716
malignant mesothelioma 2 | 3,232
non-small cell lung cancer 2 | 2,890
pituitary cancer 2 | 1,972
psoriasis 2 | 6,694
spina bifida 2 | 1,074
subependymal giant cell astrocytoma 2 | 2,287
ulcerative colitis 2 | 1,819
urothelial carcinoma 2 | 318
Acquired immunodeficiency syndrome 1 | 197
Acute Promyelocytic Leukemia 1 | 40
Adenocarcinoma 1 | 122
COPD 1 | 118
Cataract 8 multiple types 1 | 33
Childhood onset 1 | 38
Chronic kidney disease stage 5 1 | 31
Chronic obstructive pulmonary disease 1 | 184
Disease Progression 1 | 136
Down syndrome 1 | 499
Edema 1 | 81
Esophageal Squamous Cell Carcinoma 1 | 77
Essential Hypertension 1 | 94
Focal glomerulosclerosis 1 | 37
Heart disease 1 | 306
Hypoalbuminemia 1 | 24
Infarction, Middle Cerebral Artery 1 | 33
Kidney Neoplasm 1 | 29
Kidney Neoplasms 1 | 37
Kidney disease 1 | 430
Leukemia, Promyelocytic, Acute 1 | 36
Lymphopenia 1 | 67
Multiple Sclerosis 1 | 540
Nephrotic Syndrome 1 | 78
Neuroblastoma 1 | 80
Nonsyndromic deafness 1 | 142
Orofacial cleft 1 | 54
Pancreatic Neoplasm 1 | 85
Pancreatic Neoplasms 1 | 85
Pick disease 1 | 1,894
Polycystic ovary syndrome 1 | 360
Progressive disorder 1 | 142
Proteinuria 1 | 144
Schizophrenia 1 | 1,160
Severe Dengue 1 | 3
Skin cancer 1 | 469
Squamous cell carcinoma of esophagus 1 | 77
Stomach Neoplasms 1 | 300
Thyroid Neoplasm 1 | 37
Thyroid Neoplasms 1 | 34
Usher syndrome 1 | 32
Zellweger syndrome 1 | 37
active ulcerative colitis 1 | 764
acute myeloid leukemia 1 | 783
astrocytoma 1 | 1,146
chronic rhinosinusitis 1 | 512
colon cancer 1 | 1,478
cystic fibrosis 1 | 1,696
cystic fibrosis and chronic rhinosinusitis 1 | 214
esophageal adenocarcinoma 1 | 737
hereditary spastic paraplegia 1 | 318
intraductal papillary-mucinous adenoma (IPMA) 1 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 1 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 1 | 3,291
juvenile dermatomyositis 1 | 1,187
nasopharyngeal carcinoma 1 | 1,058
nephrosclerosis 1 | 333
non diabetic and post-ischemic heart failure 1 | 200
pancreatic ductal adenocarcinoma liver metastasis 1 | 1,962
pediatric high grade glioma 1 | 1,064
posterior fossa group A ependymoma 1 | 468
posterior fossa group B ependymoma 1 | 416
primary Sjogren syndrome 1 | 735
tuberculosis 1 | 2,010
type II diabetes mellitus and post-ischemic heart failure 1 | 88

Tissue

Cardiovascular System 11 | 15,192
Digestive Tract 11 | 17,369
Endocrine System 11 | 18,159
Female tissues 11 | 17,400
Liver and Pancreas 11 | 16,750
Male tissues 11 | 17,142
Nervous System 11 | 16,725
Respiratory system 11 | 16,393
Skin and soft tissues 11 | 17,230
Urinary Tract 11 | 16,678
Blood and immune system 10 | 16,909

Target Family

Non-IDG 7 | 12,091
Enzyme 3 | 4,145
Kinase 1 | 634

GO Function

Ras GTPase binding 11 | 11
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Ras association domain-containing protein 5 RASSF5 Tbio Non-IDG -1.81149 71.3 155
Calcium and integrin-binding protein 1 CIB1 Tbio Non-IDG -2.08897 121.1 264
Rap guanine nucleotide exchange factor 4 RAPGEF4 Tchem Non-IDG -2.46995 289.7 118
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 PLCE1 Tbio Enzyme -1.96455 94.9 28
Rap1 GTPase-activating protein 1 RAP1GAP Tbio Enzyme -1.86555 64.9 168
Diacylglycerol kinase iota DGKI Tbio Enzyme -0.89505 7.70 152
SH3 domain-binding protein 4 SH3BP4 Tbio Non-IDG -0.65493 4.55 143
Afadin AFDN Tbio Non-IDG -2.16280 151.2 200
Target of rapamycin complex 2 subunit MAPKAP1 MAPKAP1 Tbio Non-IDG -2.01676 101.3 244
Sphingosine kinase 2 SPHK2 Tchem Kinase -2.21878 154.9 314