Development Level

Tbio 29 | 11,651
Tdark 2 | 6,593
Tchem 1 | 1,388

IMPC Phenotype

preweaning lethality, complete... 4 | 979
abnormal embryo size 2 | 220
embryonic lethality prior to t... 2 | 278
preweaning lethality, incomple... 2 | 499
abnormal behavior 1 | 298
abnormal blood vessel morpholo... 1 | 5
abnormal craniofacial morpholo... 1 | 33
abnormal facial morphology 1 | 17
abnormal forebrain morphology 1 | 10
abnormal heart morphology 1 | 162
abnormal hindbrain morphology 1 | 10
abnormal lens morphology 1 | 81
abnormal midbrain morphology 1 | 10
abnormal neural tube closure 1 | 46
abnormal placenta size 1 | 20
abnormal retinal blood vessel ... 1 | 26
cataract 1 | 92
decreased circulating alkaline... 1 | 46
decreased circulating glucose ... 1 | 126
decreased circulating iron lev... 1 | 32
decreased circulating lipase l... 1 | 3
decreased lymphocyte cell numb... 1 | 83
decreased vertical activity 1 | 208
edema 1 | 59
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
enlarged heart 1 | 210
increased body temperature 1 | 9
increased monocyte cell number 1 | 63

Disease

Carcinoma 24 | 11,493
ovarian cancer 16 | 8,520
psoriasis 14 | 6,694
lung cancer 12 | 4,740
osteosarcoma 12 | 7,950
group 3 medulloblastoma 11 | 4,104
medulloblastoma, large-cell 11 | 6,241
glioblastoma 10 | 5,792
atypical teratoid / rhabdoid tumor 8 | 5,112
Multiple myeloma 7 | 1,332
primitive neuroectodermal tumor 7 | 3,035
Breast cancer 6 | 3,578
Pick disease 6 | 1,894
acute quadriplegic myopathy 6 | 1,158
ependymoma 6 | 4,679
lung adenocarcinoma 6 | 2,716
non-small cell lung cancer 6 | 2,890
oligodendroglioma 6 | 2,850
Waldenstrons macroglobulinemia 5 | 765
astrocytic glioma 5 | 2,597
dermatomyositis 5 | 966
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
invasive ductal carcinoma 5 | 2,951
tuberculosis 5 | 2,010
Atopic dermatitis 4 | 952
Cancer 4 | 2,499
HIV Infections 4 | 102
Kidney cancer 4 | 2,613
colon cancer 4 | 1,478
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
juvenile dermatomyositis 4 | 1,187
nasopharyngeal carcinoma 4 | 1,058
non primary Sjogren syndrome sicca 4 | 891
pancreatic cancer 4 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
pediatric high grade glioma 4 | 1,064
subependymal giant cell astrocytoma 4 | 2,287
Adenocarcinoma of lung 3 | 142
Disease Models, Animal 3 | 155
Schizophrenia 3 | 1,160
adrenocortical carcinoma 3 | 1,428
adult high grade glioma 3 | 3,801
group 4 medulloblastoma 3 | 1,855
hepatocellular carcinoma 3 | 547
malignant mesothelioma 3 | 3,232
Amyotrophic lateral sclerosis 2 | 451
Influenza 2 | 142
Multiple Sclerosis 2 | 540
Rheumatoid arthritis 2 | 1,191
astrocytoma 2 | 1,146
breast carcinoma 2 | 1,638
esophageal adenocarcinoma 2 | 737
hereditary spastic paraplegia 2 | 318
inflammatory breast cancer 2 | 286
interstitial lung disease 2 | 298
lung carcinoma 2 | 2,843
non-small cell lung carcinoma 2 | 317
primary pancreatic ductal adenocarcinoma 2 | 1,109
spina bifida 2 | 1,074
triple-A syndrome 2 | 17
Acquired metabolic disease 1 | 336
Adult T-Cell Lymphoma/Leukemia 1 | 30
Alcoholic Intoxication, Chronic 1 | 289
Arrhythmogenic right ventricular cardiomyopathy 1 | 30
Brain disease 1 | 96
Breast Neoplasms 1 | 445
Brugada syndrome 1 | 29
Carcinoma, Hepatocellular 1 | 228
Cardiovascular system disease 1 | 246
Colonic Neoplasms 1 | 142
Colorectal Neoplasms 1 | 243
Endometrial Neoplasms 1 | 55
Frontotemporal dementia 1 | 51
Gaucher disease type 1 1 | 180
Hyperphosphatemia 1 | 32
Keratoconus 1 | 113
Kidney Neoplasms 1 | 37
Large intestine cancer 1 | 126
Leukemia-Lymphoma, Adult T-Cell 1 | 30
Liver carcinoma 1 | 240
Lung Neoplasms 1 | 232
Lymphoid leukemia 1 | 160
Mammary Neoplasms 1 | 425
Microsatellite Instability 1 | 12
Right atrial isomerism 1 | 29
Salmonellosis 1 | 42
Secondary hyperparathyroidism 1 | 6
Squamous cell carcinoma 1 | 129
Stomach Neoplasms 1 | 300
Substance-Related Disorders 1 | 115
Uterine Cervical Neoplasm 1 | 25
Uterine Cervical Neoplasms 1 | 26
Weight Gain 1 | 100
Wolff-Parkinson-White syndrome 1 | 19
adrenocortical adenoma 1 | 131
atypical teratoid/rhabdoid tumor 1 | 357
medulloblastoma 1 | 720
permanent atrial fibrillation 1 | 45
posterior fossa group B ependymoma 1 | 416

Tissue

Endocrine System 32 | 18,159
Blood and immune system 31 | 16,909
Cardiovascular System 31 | 15,192
Digestive Tract 31 | 17,369
Female tissues 31 | 17,400
Liver and Pancreas 31 | 16,750
Male tissues 31 | 17,142
Nervous System 31 | 16,725
Respiratory system 31 | 16,393
Skin and soft tissues 31 | 17,230
Urinary Tract 31 | 16,678

Target Family

Non-IDG 28 | 12,091
Enzyme 4 | 4,145

GO Function

Ran GTPase binding 32 | 32
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Exportin-4 XPO4 Tbio Non-IDG -1.62873 40.7 26
Ran-specific GTPase-activating protein RANBP1 Tbio Enzyme -1.80548 64.8 193
Nuclear pore complex protein Nup50 NUP50 Tbio Non-IDG -1.18445 15.9 270
Importin subunit beta-1 KPNB1 Tbio Non-IDG -1.63038 38.8 174
Ran-binding protein 9 RANBP9 Tbio Non-IDG -1.64099 53.0 152
Ran-binding protein 3-like RANBP3L Tdark Non-IDG -0.25756 2.29 69
Ran guanine nucleotide release factor RANGRF Tbio Enzyme -1.33723 22.7 35
E3 SUMO-protein ligase RanBP2 RANBP2 Tbio Enzyme -2.24609 178.6 172
Baculoviral IAP repeat-containing protein 5 BIRC5 Tchem Non-IDG -2.19532 132.5 1167
Exportin-1 XPO1 Tbio Non-IDG -3.14385 1273.6 200