Development Level

Tbio 39 | 11,445
Tdark 6 | 6,588

IMPC Phenotype

decreased bone mineral content 3 | 151
abnormal bone structure 2 | 187
increased circulating alkaline... 2 | 122
preweaning lethality, complete... 2 | 979
preweaning lethality, incomple... 2 | 499
abnormal behavior 1 | 298
abnormal motor capabilities-co... 1 | 5
abnormal spinal cord morpholog... 1 | 9
decreased B cell number 1 | 5
decreased body weight 1 | 161
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 53
decreased circulating chloride... 1 | 30
decreased circulating glucose ... 1 | 126
decreased circulating insulin ... 1 | 76
decreased erythrocyte cell num... 1 | 62
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased lean body mass 1 | 135
decreased leukocyte cell numbe... 1 | 73
decreased mature B cell number 1 | 7
decreased mean corpuscular hem... 1 | 50
decreased prepulse inhibition 1 | 82
decreased total retina thickne... 1 | 17
decreased vertical activity 1 | 208
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
hydrometra 1 | 53
improved glucose tolerance 1 | 79
increased fasted circulating g... 1 | 76
increased grip strength 1 | 41
increased heart weight 1 | 62
increased lean body mass 1 | 172
increased mean corpuscular vol... 1 | 92
increased mean platelet volume 1 | 45
increased neutrophil cell numb... 1 | 46
increased red blood cell distr... 1 | 34
increased total body fat amoun... 1 | 134
prenatal lethality prior to he... 1 | 87
short tibia 1 | 97
thrombocytopenia 1 | 56

Disease

Carcinoma 33 | 11,493
osteosarcoma 26 | 7,950
ovarian cancer 26 | 8,520
Kidney cancer 17 | 2,613
medulloblastoma, large-cell 13 | 6,241
glioblastoma 12 | 5,792
atypical teratoid / rhabdoid tumor 11 | 5,112
psoriasis 11 | 6,694
adult high grade glioma 9 | 3,801
ependymoma 9 | 4,679
lung carcinoma 9 | 2,843
Pick disease 8 | 1,894
intraductal papillary-mucinous adenoma (IPMA) 8 | 2,955
group 4 medulloblastoma 7 | 1,855
intraductal papillary-mucinous carcinoma (IPMC) 7 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,291
lung cancer 7 | 4,740
Astrocytoma, Pilocytic 6 | 3,081
interstitial cystitis 6 | 2,312
invasive ductal carcinoma 6 | 2,951
malignant mesothelioma 6 | 3,232
Breast cancer 5 | 3,578
dermatomyositis 5 | 966
group 3 medulloblastoma 5 | 4,104
juvenile dermatomyositis 5 | 1,187
tuberculosis 5 | 2,010
Multiple myeloma 4 | 1,332
Rheumatoid arthritis 4 | 1,191
Waldenstrons macroglobulinemia 4 | 765
astrocytoma 4 | 1,146
non primary Sjogren syndrome sicca 4 | 891
oligodendroglioma 4 | 2,850
ulcerative colitis 4 | 1,819
Neurodegenerative disease 3 | 414
acute quadriplegic myopathy 3 | 1,158
breast carcinoma 3 | 1,638
cutaneous lupus erythematosus 3 | 1,057
ductal carcinoma in situ 3 | 1,745
lung adenocarcinoma 3 | 2,716
non-small cell lung cancer 3 | 2,890
pediatric high grade glioma 3 | 1,064
pituitary cancer 3 | 1,972
primary pancreatic ductal adenocarcinoma 3 | 1,109
sonic hedgehog group medulloblastoma 3 | 467
spina bifida 3 | 1,074
tuberculosis and treatment for 6 months 3 | 409
Acquired flat foot 2 | 72
Acquired scoliosis 2 | 281
Amyotrophic lateral sclerosis 2 | 451
Atopic dermatitis 2 | 952
Autosomal recessive predisposition 2 | 1,442
Centronuclear myopathy 2 | 27
Charcot-Marie-Tooth disease 2 | 62
Chronic Lymphocytic Leukemia 2 | 262
Curvature of spine 2 | 282
Downward slant of palpebral fissure 2 | 158
Epilepsy 2 | 792
Flatfoot 2 | 73
Liver cancer 2 | 604
Muscle hypotonia 2 | 571
Neuropathy 2 | 261
Schizophrenia 2 | 1,160
active Crohn's disease 2 | 922
acute myeloid leukemia 2 | 783
aldosterone-producing adenoma 2 | 665
astrocytic glioma 2 | 2,597
cystic fibrosis 2 | 1,696
diabetes mellitus 2 | 1,728
gastric cancer 2 | 459
hepatocellular carcinoma 2 | 547
mucosa-associated lymphoid tissue lymphoma 2 | 484
pancreatic cancer 2 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
primitive neuroectodermal tumor 2 | 3,035
subependymal giant cell astrocytoma 2 | 2,287
Atrophic gastritis 1 | 5
Azoospermia 1 | 110
Bleeding time prolonged 1 | 31
COPD 1 | 118
Cerebral amyloid angiopathy 1 | 13
Ciliopathy 1 | 71
Cocaine abuse 1 | 19
Common variable immunodeficiency 1 | 101
Ecchymosis 1 | 66
Hermansky-Pudlak syndrome 1 | 42
Hirsutism 1 | 47
Hypertrophy of breast 1 | 17
Increased tendency to bruise 1 | 66
Juvenile astrocytoma 1 | 3
Mastitis 1 | 48
Meningitis 1 | 67
Narcolepsy 1 | 72
Osteitis Deformans 1 | 11
Paget's disease of bone 1 | 36
Sarcoma 1 | 62
Tinea capitis 1 | 14
inflammatory breast cancer 1 | 286
non-inflammatory breast cancer 1 | 66
sarcoidosis 1 | 370
triple-A syndrome 1 | 17

Tissue

Blood and immune system 45 | 16,909
Cardiovascular System 45 | 15,192
Digestive Tract 45 | 17,369
Endocrine System 45 | 18,159
Female tissues 45 | 17,400
Liver and Pancreas 45 | 16,750
Male tissues 45 | 17,142
Nervous System 45 | 16,725
Respiratory system 45 | 16,393
Skin and soft tissues 45 | 17,230
Urinary Tract 45 | 16,678

Target Family

Non-IDG 43 | 12,091
Enzyme 2 | 4,145

GO Function

Rab guanyl-nucleotide exchange... 45 | 45
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Trafficking protein particle complex subunit 2-like protein TRAPPC2L Tdark Non-IDG -0.18066 0.74 35
MAP kinase-activating death domain protein MADD Tbio Enzyme -1.86555 79.6 121
DENN domain-containing protein 2A DENND2A Tbio Non-IDG 0.00000 34
Trafficking protein particle complex subunit 8 TRAPPC8 Tdark Non-IDG -1.08378 10.2 5
Suppression of tumorigenicity 5 protein ST5 Tbio Non-IDG -2.14294 141.9 161
Ankyrin repeat domain-containing protein 27 ANKRD27 Tbio Non-IDG -1.12548 14.6 65
GTPase-activating protein and VPS9 domain-containing protein 1 GAPVD1 Tbio Enzyme -0.69565 4.71 73
Protein DENND6B DENND6B Tbio Non-IDG 0.95 0.11 35
Rab-3A-interacting protein RAB3IP Tbio Non-IDG -1.03500 11.6 89
Myotubularin-related protein 13 SBF2 Tbio Non-IDG -1.38747 24.7 15