Development Level

Tbio 111 | 10,625
Tdark 44 | 7,003
Tchem 7 | 1,890

IMPC Term

preweaning lethality, complete... 5 | 633
abnormal bone structure 4 | 131
increased exploration in new e... 3 | 56
abnormal bone mineralization 2 | 55
decreased T cell number 2 | 31
decreased body weight 2 | 174
decreased bone mineral density 2 | 126
decreased circulating chloride... 2 | 32
decreased circulating choleste... 2 | 85
decreased circulating triglyce... 2 | 83
decreased total body fat amoun... 2 | 186
embryonic lethality prior to t... 2 | 187
increased bone mineral content 2 | 92
increased mean corpuscular vol... 2 | 91
preweaning lethality, incomple... 2 | 260
abnormal behavior 1 | 226
abnormal coat/ hair morphology 1 | 18
abnormal cornea morphology 1 | 24
abnormal embryo size 1 | 112
abnormal eye morphology 1 | 38
abnormal forebrain development 1 | 18
abnormal heart morphology 1 | 51
abnormal hindbrain development 1 | 24
abnormal humerus morphology 1 | 11
abnormal neural tube closure 1 | 37
abnormal retina morphology 1 | 100
abnormal retinal pigmentation 1 | 61
abnormal skin coloration 1 | 18
abnormal spleen morphology 1 | 36
abnormal vibrissa morphology 1 | 17
corneal opacity 1 | 25
decreased CD4-positive, alpha ... 1 | 19
decreased CD8-positive, alpha-... 1 | 26
decreased IgG1 level 1 | 4
decreased anxiety-related resp... 1 | 12
decreased bone mineral content 1 | 157
decreased circulating HDL chol... 1 | 77
decreased circulating free fat... 1 | 39
decreased circulating fructosa... 1 | 31
decreased circulating glucose ... 1 | 121
decreased circulating glycerol... 1 | 19
decreased circulating insulin ... 1 | 75
decreased circulating phosphat... 1 | 15
decreased circulating serum al... 1 | 79
decreased circulating sodium l... 1 | 18
decreased circulating total pr... 1 | 41
decreased erythrocyte cell num... 1 | 43
decreased fasted circulating g... 1 | 49
decreased grip strength 1 | 123
decreased hematocrit 1 | 25
decreased hemoglobin content 1 | 53
decreased lean body mass 1 | 195
decreased mature B cell number 1 | 25
enlarged heart 1 | 111
female infertility 1 | 34
hypoactivity 1 | 89
increased B cell number 1 | 23
increased T cell number 1 | 15
increased bone mineral density 1 | 52
increased circulating alkaline... 1 | 119
increased fasted circulating g... 1 | 68
increased grip strength 1 | 83
increased lactate dehydrogenas... 1 | 3
increased lean body mass 1 | 107
increased mean corpuscular hem... 1 | 93
male infertility 1 | 62
prenatal lethality prior to he... 1 | 64
thick ventricular wall 1 | 7
trunk curl 1 | 15
vertebral fusion 1 | 23

Disease

ovarian cancer 70 | 8,484
osteosarcoma 67 | 7,933
psoriasis 66 | 6,685
medulloblastoma, large-cell 52 | 6,234
Cancer 47 | 2,346
lung cancer 44 | 4,466
glioblastoma 35 | 5,572
atypical teratoid / rhabdoid tumor 34 | 4,369
Breast cancer 33 | 3,094
malignant mesothelioma 30 | 3,162
intraductal papillary-mucinous carcinoma (IPMC) 27 | 2,988
invasive ductal carcinoma 27 | 2,950
non-small cell lung cancer 27 | 2,798
intraductal papillary-mucinous adenoma (IPMA) 26 | 2,956
intraductal papillary-mucinous neoplasm (IPMN) 26 | 3,289
pancreatic cancer 23 | 2,300
interstitial cystitis 22 | 2,299
lung adenocarcinoma 22 | 2,713
lung carcinoma 22 | 2,844
group 3 medulloblastoma 21 | 2,254
pituitary cancer 21 | 1,972
astrocytic glioma 20 | 2,241
oligodendroglioma 20 | 2,849
pediatric high grade glioma 20 | 2,712
primitive neuroectodermal tumor 20 | 3,031
breast carcinoma 19 | 1,614
ependymoma 19 | 2,514
sonic hedgehog group medulloblastoma 19 | 1,482
ductal carcinoma in situ 18 | 1,745
pilocytic astrocytoma 18 | 3,086
Pick disease 17 | 1,893
group 4 medulloblastoma 17 | 1,875
posterior fossa group A ependymoma 17 | 1,511
Carcinoma 16 | 2,147
diabetes mellitus 15 | 1,663
medulloblastoma 15 | 1,524
cystic fibrosis 12 | 1,665
subependymal giant cell astrocytoma 12 | 2,287
tuberculosis 12 | 1,557
ulcerative colitis 12 | 2,087
Obesity 11 | 616
Rheumatoid Arthritis 11 | 1,160
atypical teratoid/rhabdoid tumor 11 | 1,095
colon cancer 11 | 1,475
primary pancreatic ductal adenocarcinoma 11 | 1,271
Intellectual disability 10 | 573
Multiple myeloma 10 | 1,327
adult high grade glioma 10 | 2,148
astrocytoma 10 | 1,493
primary Sjogren syndrome 10 | 789
spina bifida 10 | 1,064
Craniofacial Abnormalities 9 | 147
Mammary Neoplasms 9 | 410
acute quadriplegic myopathy 9 | 1,157
adrenocortical carcinoma 9 | 1,427
Leukemia, Myelocytic, Acute 8 | 113
Prostatic Neoplasms 8 | 471
Waldenstrons macroglobulinemia 8 | 765
acute myeloid leukemia 8 | 780
cutaneous lupus erythematosus 8 | 1,056
fibroadenoma 8 | 557
pancreatic carcinoma 8 | 567
posterior fossa group B ependymoma 8 | 1,530
tuberculosis and treatment for 6 months 8 | 686
Atopic dermatitis 7 | 944
Polycystic Ovary Syndrome 7 | 332
nasopharyngeal carcinoma 7 | 1,056
nephrosclerosis 7 | 329
non primary Sjogren syndrome sicca 7 | 840
Acquired metabolic disease 6 | 267
Glaucoma 6 | 134
Kidney disease 6 | 396
Lung Neoplasms 6 | 171
Stomach Neoplasms 6 | 282
Vascular disease 6 | 281
dermatomyositis 6 | 933
gastric cancer 6 | 430
gastric carcinoma 6 | 832
juvenile dermatomyositis 6 | 1,189
Alzheimer's disease 5 | 644
Autistic Disorder 5 | 320
Corneal disease 5 | 32
Juvenile arthritis 5 | 124
Liver carcinoma 5 | 217
active Crohn's disease 5 | 918
active ulcerative colitis 5 | 477
chronic rhinosinusitis 5 | 512
facioscapulohumeral dystrophy 5 | 286
inflammatory breast cancer 5 | 404
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,795
urothelial carcinoma 5 | 318
Endometriosis 4 | 535
Heart disease 4 | 279
Multiple Sclerosis 4 | 498
Schizophrenia 4 | 501
aldosterone-producing adenoma 4 | 664
chronic lymphosyte leukemia 4 | 232
esophageal adenocarcinoma 4 | 737
hepatocellular carcinoma 4 | 532
progressive supranuclear palsy 4 | 674

Tissue

Endocrine System 160 | 18,512
Female tissues 160 | 18,647
Nervous System 160 | 18,561
Digestive Tract 159 | 18,473
Urinary Tract 158 | 18,444
Skin and soft tissues 157 | 18,115
Liver and Pancreas 153 | 18,136
Male tissues 153 | 17,969
Blood and immune system 151 | 17,995
Cardiovascular System 151 | 17,958
Respiratory system 149 | 17,484

Target Family

Transcription Factor 133 | 1,400
Non-IDG 27 | 11,971
Enzyme 1 | 4,146
Kinase 1 | 634

GO Function

RNA polymerase II transcriptio... 162 | 162
metal ion binding 1,917 | 1,917
ATP binding 1,467 | 1,467
DNA binding 1,432 | 1,432
zinc ion binding 1,155 | 1,155
poly(A) RNA binding 1,107 | 1,107
transcription factor activity,... 853 | 853
calcium ion binding 695 | 695
G-protein coupled receptor act... 661 | 661
protein homodimerization activ... 569 | 569
RNA binding 445 | 445
olfactory receptor activity 424 | 424
sequence-specific DNA binding 398 | 398
GTP binding 374 | 374
chromatin binding 372 | 372
protein serine/threonine kinas... 336 | 336
RNA polymerase II core promote... 332 | 332
identical protein binding 311 | 311
nucleotide binding 311 | 311
receptor binding 303 | 303
protein kinase binding 289 | 289
enzyme binding 286 | 286
cadherin binding involved in c... 277 | 277
GTPase activator activity 273 | 273
ubiquitin protein ligase bindi... 258 | 258
ubiquitin-protein transferase ... 253 | 253
serine-type endopeptidase acti... 246 | 246
transcription coactivator acti... 241 | 241
transcription factor binding 240 | 240
structural molecule activity 232 | 232
GTPase activity 231 | 231
transcriptional activator acti... 230 | 230
ligase activity 227 | 227
protein heterodimerization act... 227 | 227
structural constituent of ribo... 212 | 212
transcription regulatory regio... 202 | 202
transmembrane signaling recept... 201 | 201
RNA polymerase II regulatory r... 200 | 200
receptor activity 200 | 200
transcription corepressor acti... 198 | 198
magnesium ion binding 197 | 197
signal transducer activity 196 | 196
nucleic acid binding 184 | 184
protein kinase activity 183 | 183
carbohydrate binding 180 | 180
ubiquitin protein ligase activ... 173 | 173
heparin binding 160 | 160
iron ion binding 141 | 141
lipid binding 136 | 136
transporter activity 136 | 136
actin binding 133 | 133
ATPase activity 132 | 132
protein C-terminus binding 129 | 129
heme binding 127 | 127
microtubule binding 123 | 123
protein tyrosine kinase activi... 119 | 119
cytokine activity 118 | 118
Ras guanyl-nucleotide exchange... 113 | 113
mRNA binding 112 | 112
metalloendopeptidase activity 112 | 112
transcriptional repressor acti... 110 | 110
structural constituent of cyto... 108 | 108
Rab GTPase binding 105 | 105
antigen binding 104 | 104
protein domain specific bindin... 102 | 102
peptide antigen binding 101 | 101
guanyl-nucleotide exchange fac... 98 | 98
protein complex binding 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 92 | 92
oxidoreductase activity 91 | 91
transcriptional activator acti... 91 | 91
actin filament binding 89 | 89
hydrolase activity 89 | 89
ion channel binding 89 | 89
protein tyrosine phosphatase a... 88 | 88
electron carrier activity 87 | 87
protease binding 87 | 87
histone binding 86 | 86
integrin binding 83 | 83
growth factor activity 82 | 82
phospholipid binding 82 | 82
single-stranded DNA binding 81 | 81
unfolded protein binding 77 | 77
kinase activity 75 | 75
thiol-dependent ubiquitin-spec... 75 | 75
phosphatidylinositol binding 74 | 74
calmodulin binding 73 | 73
histone deacetylase binding 73 | 73
Rho guanyl-nucleotide exchange... 72 | 72
drug binding 71 | 71
double-stranded DNA binding 70 | 70
peptidase activity 70 | 70
protein N-terminus binding 70 | 70
virus receptor activity 68 | 68
beta-catenin binding 67 | 67
microtubule motor activity 67 | 67
protein transporter activity 67 | 67
calcium channel activity 66 | 66
ubiquitin binding 66 | 66

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Forkhead box protein M1 FOXM1 Tbio Transcription Factor -3.09305 1275.4 345
Zinc finger and SCAN domain-containing protein 1 ZSCAN1 Tbio Transcription Factor -1.37888 19.7 80
Transcription factor SOX-30 SOX30 Tbio Transcription Factor -0.69660 5.92 144
Zinc finger and SCAN domain-containing protein 29 ZSCAN29 Tdark Transcription Factor 0.70 0.10 68
Forkhead box protein L2 FOXL2 Tbio Transcription Factor -2.76212 610.7 220
Forkhead box protein P3 FOXP3 Tbio Transcription Factor -3.60057 5680.3 1162
Prohibitin PHB Tbio Non-IDG -2.65435 467.0 464
Transcriptional regulator ERG ERG Tchem Transcription Factor -2.49936 317.4 284
Zinc finger BED domain-containing protein 5 ZBED5 Tdark Non-IDG 0.12 0.58 45
Protein ZBED8 ZBED8 Tdark Non-IDG 0.60 0.17 19