Development Level

Tbio 35 | 11,445
Tchem 7 | 1,598

IMPC Phenotype

abnormal behavior 3 | 298
decreased vertical activity 3 | 208
preweaning lethality, complete... 3 | 979
hyperactivity 2 | 148
abnormal optic disc morphology 1 | 10
abnormal tooth morphology 1 | 24
absent pinna reflex 1 | 23
corneal opacity 1 | 32
decreased body weight 1 | 161
decreased circulating choleste... 1 | 93
decreased circulating fructosa... 1 | 30
decreased circulating glucose ... 1 | 126
decreased circulating serum al... 1 | 82
decreased fasted circulating g... 1 | 65
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
decreased neutrophil cell numb... 1 | 42
decreased startle reflex 1 | 75
decreased total body fat amoun... 1 | 207
enlarged heart 1 | 210
female infertility 1 | 60
increased bone mineral content 1 | 108
increased kidney weight 1 | 6
increased lean body mass 1 | 172
increased leukocyte cell numbe... 1 | 47
increased neutrophil cell numb... 1 | 46
increased startle reflex 1 | 112
irregularly shaped pupil 1 | 7
male infertility 1 | 123
prenatal lethality 1 | 28
preweaning lethality, incomple... 1 | 499
small testis 1 | 58

Disease

Carcinoma 31 | 11,493
medulloblastoma, large-cell 25 | 6,241
psoriasis 25 | 6,694
ovarian cancer 24 | 8,520
osteosarcoma 20 | 7,950
lung cancer 19 | 4,740
group 3 medulloblastoma 18 | 4,104
glioblastoma 17 | 5,792
Breast cancer 16 | 3,578
Cancer 16 | 2,499
atypical teratoid / rhabdoid tumor 16 | 5,112
Kidney cancer 12 | 2,613
malignant mesothelioma 12 | 3,232
non-small cell lung cancer 12 | 2,890
oligodendroglioma 12 | 2,850
primitive neuroectodermal tumor 12 | 3,035
adult high grade glioma 11 | 3,801
ependymoma 11 | 4,679
invasive ductal carcinoma 11 | 2,951
lung adenocarcinoma 11 | 2,716
subependymal giant cell astrocytoma 11 | 2,287
Intellectual disability 9 | 1,016
astrocytoma 9 | 1,146
intraductal papillary-mucinous carcinoma (IPMC) 9 | 2,989
Cryptorchidism 8 | 296
Multiple myeloma 8 | 1,332
acute quadriplegic myopathy 8 | 1,158
astrocytic glioma 8 | 2,597
colon cancer 8 | 1,478
pancreatic cancer 8 | 2,398
Congenital heart disease 7 | 93
Dull intelligence 7 | 645
Epilepsy 7 | 792
Low intelligence 7 | 645
Mental Retardation 7 | 645
Mental deficiency 7 | 645
Poor school performance 7 | 645
Seizures 7 | 596
Strabismus 7 | 270
ductal carcinoma in situ 7 | 1,745
lung carcinoma 7 | 2,843
Broad flat nasal bridge 6 | 236
Cognitive delay 6 | 608
Concave bridge of nose 6 | 195
Depressed nasal bridge 6 | 195
Depressed nasal root/bridge 6 | 195
Global developmental delay 6 | 608
Heart disease 6 | 306
Liver cancer 6 | 604
Mental and motor retardation 6 | 608
Muscle hypotonia 6 | 571
Nasal bridge wide 6 | 236
Schizophrenia 6 | 1,160
Small head 6 | 374
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,955
ulcerative colitis 6 | 1,819
Adenoid Cystic Carcinoma 5 | 99
Bilateral fifth finger clinodactyly 5 | 110
Carcinoma, Adenoid Cystic 5 | 99
Congenital deafness 5 | 185
Constipation 5 | 181
Curvature of little finger 5 | 110
Deafness 5 | 198
Depressed nasal ridge 5 | 51
Dyschezia 5 | 135
Feeding difficulties in infancy 5 | 175
Fetal Growth Retardation 5 | 189
Hearing Loss, Partial 5 | 185
Infant, Small for Gestational Age 5 | 176
Intrauterine retardation 5 | 176
Penile hypospadias 5 | 106
Prostatic Neoplasms 5 | 495
Rheumatoid arthritis 5 | 1,191
Short stature 5 | 531
cystic fibrosis 5 | 1,696
diabetes mellitus 5 | 1,728
hearing impairment 5 | 199
interstitial cystitis 5 | 2,312
juvenile dermatomyositis 5 | 1,187
pituitary cancer 5 | 1,972
Acquired scoliosis 4 | 281
Astrocytoma, Pilocytic 4 | 3,081
Autosomal recessive predisposition 4 | 1,442
Bipolar Disorder 4 | 666
Coarse facial features 4 | 108
Curvature of spine 4 | 282
Glaucoma 4 | 239
Microstomia 4 | 78
Short philtrum 4 | 53
Waldenstrons macroglobulinemia 4 | 765
aldosterone-producing adenoma 4 | 665
cutaneous lupus erythematosus 4 | 1,057
dermatomyositis 4 | 966
fibroadenoma 4 | 559
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
nasopharyngeal carcinoma 4 | 1,058
pediatric high grade glioma 4 | 1,064
posterior fossa group A ependymoma 4 | 468
spina bifida 4 | 1,074
tuberculosis 4 | 2,010

Tissue

Endocrine System 42 | 18,159
Female tissues 40 | 17,400
Nervous System 40 | 16,725
Skin and soft tissues 40 | 17,230
Blood and immune system 39 | 16,909
Digestive Tract 39 | 17,369
Urinary Tract 39 | 16,678
Cardiovascular System 38 | 15,192
Liver and Pancreas 38 | 16,750
Male tissues 37 | 17,142
Respiratory system 36 | 16,393

Target Family

Transcription Factor 15 | 1,400
Non-IDG 12 | 12,091
Epigenetic 8 | 242
Enzyme 6 | 4,145
Kinase 1 | 634

GO Function

RNA polymerase II transcriptio... 42 | 42
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Paired mesoderm homeobox protein 1 PRRX1 Tbio Transcription Factor -1.58479 38.8 304
Histone-arginine methyltransferase CARM1 CARM1 Tchem Epigenetic -2.04034 130.8 476
MKL/myocardin-like protein 2 MKL2 Tbio Non-IDG -1.31650 19.1 79
Zinc finger protein ZFPM2 ZFPM2 Tbio Transcription Factor -1.78912 62.9 93
Mediator of RNA polymerase II transcription subunit 12-like protein MED12L Tbio Enzyme -0.77925 5.52 14
ATP-dependent RNA helicase A DHX9 Tbio Enzyme -2.85807 734.3 204
Myocardin MYOCD Tbio Non-IDG -2.37801 242.7 84
Nuclear pore complex protein Nup98-Nup96 NUP98 Tbio Enzyme -2.26305 200.9 189
Insulin gene enhancer protein ISL-1 ISL1 Tbio Transcription Factor -2.63352 410.3 382
Arginine-glutamic acid dipeptide repeats protein RERE Tbio Transcription Factor -1.99098 95.2 128