Development Level

Tbio 37 | 10,625
Tchem 10 | 1,890
Tclin 1 | 602

IMPC Phenotype

preweaning lethality, complete... 4 | 633
decreased bone mineral density 2 | 126
decreased circulating creatini... 2 | 31
decreased circulating insulin ... 2 | 75
increased circulating choleste... 2 | 53
abnormal bone structure 1 | 131
abnormal cornea morphology 1 | 24
abnormal epididymis morphology 1 | 31
abnormal ovary morphology 1 | 3
abnormal response to new envir... 1 | 8
abnormal skin condition 1 | 6
abnormal tooth morphology 1 | 24
absent epididymis 1 | 2
absent ovary 1 | 2
absent vibrissae 1 | 14
decreased B cell number 1 | 30
decreased CD4-positive, CD25-p... 1 | 24
decreased CD8-positive, naive ... 1 | 5
decreased blood urea nitrogen ... 1 | 31
decreased bone mineral content 1 | 157
decreased circulating amylase ... 1 | 24
decreased circulating choleste... 1 | 85
decreased circulating serum al... 1 | 79
decreased circulating sodium l... 1 | 18
decreased effector memory CD8-... 1 | 24
decreased gamma-delta T cell n... 1 | 18
decreased lean body mass 1 | 195
decreased mature B cell number 1 | 25
decreased mean corpuscular hem... 1 | 19
decreased thermal nociceptive ... 1 | 4
decreased total body fat amoun... 1 | 186
embryonic lethality prior to t... 1 | 187
increased CD4-positive, alpha ... 1 | 15
increased KLRG1+ CD4 alpha bet... 1 | 5
increased KLRG1+ CD8 alpha bet... 1 | 2
increased KLRG1-positive CD4-n... 1 | 1
increased KLRG1-positive CD4-p... 1 | 3
increased KLRG1-positive NK ce... 1 | 9
increased KLRG1-positive T-hel... 1 | 2
increased KLRG1-positive gamma... 1 | 2
increased Ly6C low monocyte nu... 1 | 8
increased NK cell number 1 | 19
increased bone mineral density 1 | 52
increased circulating HDL chol... 1 | 63
increased circulating alanine ... 1 | 11
increased circulating alkaline... 1 | 119
increased circulating aspartat... 1 | 17
increased circulating free fat... 1 | 17
increased circulating sodium l... 1 | 71
increased circulating total pr... 1 | 20
increased circulating triglyce... 1 | 24
increased effector memory CD4-... 1 | 15
increased effector memory CD8-... 1 | 14
increased effector memory T-he... 1 | 5
increased eosinophil cell numb... 1 | 9
increased fasted circulating g... 1 | 68
increased lactate dehydrogenas... 1 | 3
increased lean body mass 1 | 107
increased leukocyte cell numbe... 1 | 37
increased memory CD4-positive,... 1 | 3
increased memory-marker CD4-ne... 1 | 1
increased monocyte cell number 1 | 27
increased myeloid cell number 1 | 2
increased neutrophil cell numb... 1 | 15
increased or absent threshold ... 1 | 128
increased respiratory quotient 1 | 12
increased thermal nociceptive ... 1 | 9
prenatal lethality prior to he... 1 | 64
preweaning lethality, incomple... 1 | 260
prolonged PR interval 1 | 4
tremors 1 | 34

Disease

osteosarcoma 26 | 7,933
ovarian cancer 24 | 8,491
psoriasis 24 | 6,685
Cancer 22 | 2,346
lung cancer 19 | 4,473
medulloblastoma, large-cell 19 | 6,234
atypical teratoid / rhabdoid tumor 14 | 4,369
glioblastoma 13 | 5,572
diabetes mellitus 12 | 1,663
malignant mesothelioma 11 | 3,163
non-small cell lung cancer 11 | 2,798
intraductal papillary-mucinous carcinoma (IPMC) 10 | 2,988
invasive ductal carcinoma 10 | 2,950
primitive neuroectodermal tumor 10 | 3,031
Breast cancer 9 | 3,098
colon cancer 9 | 1,475
intraductal papillary-mucinous adenoma (IPMA) 9 | 2,956
lung carcinoma 9 | 2,844
ulcerative colitis 9 | 2,087
group 3 medulloblastoma 8 | 2,254
group 4 medulloblastoma 8 | 1,875
intraductal papillary-mucinous neoplasm (IPMN) 8 | 3,289
tuberculosis 8 | 1,563
Carcinoma 7 | 2,147
Multiple myeloma 7 | 1,327
Waldenstrons macroglobulinemia 7 | 764
breast carcinoma 7 | 1,614
ependymoma 7 | 2,514
interstitial cystitis 7 | 2,299
lung adenocarcinoma 7 | 2,714
pancreatic cancer 7 | 2,300
pilocytic astrocytoma 7 | 3,086
pituitary cancer 7 | 1,972
Intellectual disability 6 | 573
acute myeloid leukemia 6 | 785
dermatomyositis 6 | 966
oligodendroglioma 6 | 2,849
pediatric high grade glioma 6 | 2,712
Epilepsy 5 | 346
Parkinson's disease 5 | 364
astrocytoma 5 | 1,493
cutaneous lupus erythematosus 5 | 1,056
medulloblastoma 5 | 1,524
primary Sjogren syndrome 5 | 788
subependymal giant cell astrocytoma 5 | 2,287
Down syndrome 4 | 548
Heat Stroke 4 | 12
Leukemia, Myelocytic, Acute 4 | 113
Liver neoplasms 4 | 108
Mammary Neoplasms 4 | 410
Obesity 4 | 616
adrenocortical carcinoma 4 | 1,427
ductal carcinoma in situ 4 | 1,745
nephrosclerosis 4 | 329
posterior fossa group A ependymoma 4 | 1,511
sonic hedgehog group medulloblastoma 4 | 1,482
Acquired metabolic disease 3 | 267
Alzheimer's disease 3 | 644
Brain Ischemia 3 | 87
Cholestasis 3 | 93
Colonic Neoplasms 3 | 126
Crohn's disease 3 | 304
Diabetes Mellitus, Non-Insulin-Dependent 3 | 161
Drug-Induced Liver Injury 3 | 118
Endometriosis 3 | 535
Hyperglycemia 3 | 120
Liver carcinoma 3 | 217
Microphthalmia 3 | 79
Neoplastic Cell Transformation 3 | 81
Osteoporosis 3 | 259
Prostatic Neoplasms 3 | 471
Rheumatoid Arthritis 3 | 1,170
Toxic encephalopathy 3 | 131
acute quadriplegic myopathy 3 | 1,157
adult high grade glioma 3 | 2,148
aldosterone-producing adenoma 3 | 664
astrocytic glioma 3 | 2,241
atypical teratoid/rhabdoid tumor 3 | 1,095
chronic lymphosyte leukemia 3 | 232
cystic fibrosis 3 | 1,670
hepatocellular carcinoma 3 | 550
inflammatory breast cancer 3 | 404
pancreatic carcinoma 3 | 567
Arthritis 2 | 248
Atopic dermatitis 2 | 944
Cerebrovascular disease 2 | 231
Crohn Disease 2 | 97
Kidney disease 2 | 397
Leukemia 2 | 88
Pick disease 2 | 1,893
Reperfusion Injury 2 | 84
Type 2 diabetes mellitus 2 | 192
Vascular disease 2 | 281
active Crohn's disease 2 | 918
chronic rhinosinusitis 2 | 512
fibroadenoma 2 | 557
nasopharyngeal carcinoma 2 | 1,056
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,795
spina bifida 2 | 1,064
tuberculosis and treatment for 6 months 2 | 686

Tissue

Female tissues 48 | 18,646
Blood and immune system 47 | 17,994
Digestive Tract 47 | 18,472
Endocrine System 47 | 18,511
Liver and Pancreas 47 | 18,135
Male tissues 47 | 17,968
Nervous System 47 | 18,560
Skin and soft tissues 47 | 18,114
Urinary Tract 47 | 18,443
Cardiovascular System 46 | 17,957
Respiratory system 46 | 17,483

Target Family

Transcription Factor 36 | 1,400
Non-IDG 6 | 11,969
Nuclear Receptor 5 | 48
Enzyme 1 | 4,146

GO Function

RNA polymerase II distal enhan... 48 | 48
metal ion binding 1,917 | 1,917
ATP binding 1,467 | 1,467
DNA binding 1,432 | 1,432
zinc ion binding 1,155 | 1,155
poly(A) RNA binding 1,107 | 1,107
transcription factor activity,... 853 | 853
calcium ion binding 695 | 695
G-protein coupled receptor act... 661 | 661
protein homodimerization activ... 569 | 569
RNA binding 445 | 445
olfactory receptor activity 424 | 424
sequence-specific DNA binding 398 | 398
GTP binding 374 | 374
chromatin binding 372 | 372
protein serine-threonine kinas... 336 | 336
RNA polymerase II core promote... 332 | 332
identical protein binding 311 | 311
nucleotide binding 311 | 311
receptor binding 303 | 303
protein kinase binding 289 | 289
enzyme binding 286 | 286
cadherin binding involved in c... 277 | 277
GTPase activator activity 273 | 273
ubiquitin protein ligase bindi... 258 | 258
ubiquitin-protein transferase ... 253 | 253
serine-type endopeptidase acti... 246 | 246
transcription coactivator acti... 241 | 241
transcription factor binding 240 | 240
structural molecule activity 232 | 232
GTPase activity 231 | 231
transcriptional activator acti... 230 | 230
ligase activity 227 | 227
protein heterodimerization act... 227 | 227
structural constituent of ribo... 212 | 212
transcription regulatory regio... 202 | 202
transmembrane signaling recept... 201 | 201
RNA polymerase II regulatory r... 200 | 200
receptor activity 200 | 200
transcription corepressor acti... 198 | 198
magnesium ion binding 197 | 197
signal transducer activity 196 | 196
nucleic acid binding 184 | 184
protein kinase activity 183 | 183
carbohydrate binding 180 | 180
ubiquitin protein ligase activ... 173 | 173
RNA polymerase II transcriptio... 162 | 162
heparin binding 160 | 160
iron ion binding 141 | 141
lipid binding 136 | 136
transporter activity 136 | 136
actin binding 133 | 133
ATPase activity 132 | 132
protein C-terminus binding 129 | 129
heme binding 127 | 127
microtubule binding 123 | 123
protein tyrosine kinase activi... 119 | 119
cytokine activity 118 | 118
Ras guanyl-nucleotide exchange... 113 | 113
mRNA binding 112 | 112
metalloendopeptidase activity 112 | 112
transcriptional repressor acti... 110 | 110
structural constituent of cyto... 108 | 108
Rab GTPase binding 105 | 105
antigen binding 104 | 104
protein domain specific bindin... 102 | 102
peptide antigen binding 101 | 101
guanyl-nucleotide exchange fac... 98 | 98
protein complex binding 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 92 | 92
oxidoreductase activity 91 | 91
transcriptional activator acti... 91 | 91
actin filament binding 89 | 89
hydrolase activity 89 | 89
ion channel binding 89 | 89
protein tyrosine phosphatase a... 88 | 88
electron carrier activity 87 | 87
protease binding 87 | 87
histone binding 86 | 86
integrin binding 83 | 83
growth factor activity 82 | 82
phospholipid binding 82 | 82
single-stranded DNA binding 81 | 81
unfolded protein binding 77 | 77
kinase activity 75 | 75
thiol-dependent ubiquitin-spec... 75 | 75
phosphatidylinositol binding 74 | 74
calmodulin binding 73 | 73
histone deacetylase binding 73 | 73
Rho guanyl-nucleotide exchange... 72 | 72
drug binding 71 | 71
double-stranded DNA binding 70 | 70
peptidase activity 70 | 70
protein N-terminus binding 70 | 70
virus receptor activity 68 | 68
beta-catenin binding 67 | 67
microtubule motor activity 67 | 67
protein transporter activity 67 | 67
calcium channel activity 66 | 66
ubiquitin binding 66 | 66

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Transcription factor PU.1 SPI1 Tbio Transcription Factor -3.03044 1092.0 356
Transcription regulator protein BACH2 BACH2 Tbio Transcription Factor -1.84608 77.3 159
POU domain, class 4, transcription factor 1 POU4F1 Tbio Transcription Factor -2.16263 143.8 96
Pre-B-cell leukemia transcription factor 3 PBX3 Tbio Transcription Factor -1.47272 26.8 170
Paired box protein Pax-4 PAX4 Tbio Transcription Factor -2.10934 137.7 190
Homeobox protein SIX3 SIX3 Tbio Transcription Factor -2.83160 648.7 196
Nuclear factor erythroid 2-related factor 1 NFE2L1 Tbio Transcription Factor -1.51817 36.8 131
Heterogeneous nuclear ribonucleoproteins C1/C2 HNRNPC Tchem Non-IDG -2.03916 106.5 306
Musculin MSC Tbio Transcription Factor -2.15258 144.9 156
Endothelial transcription factor GATA-2 GATA2 Tbio Transcription Factor -2.66241 429.5 329