Development Level

Tbio 16 | 11,178
Tchem 5 | 1,885
Tdark 1 | 6,569

IMPC Phenotype

preweaning lethality, complete... 5 | 979
embryonic lethality prior to o... 3 | 239
embryonic lethality prior to t... 2 | 278
hypoactivity 2 | 132
preweaning lethality, incomple... 2 | 499
abnormal behavior 1 | 298
abnormal tooth morphology 1 | 24
decreased body weight 1 | 161
decreased circulating creatine... 1 | 4
decreased circulating serum al... 1 | 82
decreased coping response 1 | 8
decreased lean body mass 1 | 135
decreased red blood cell distr... 1 | 41
hyperactivity 1 | 148
impaired glucose tolerance 1 | 75
increased circulating HDL chol... 1 | 80
increased circulating LDL chol... 1 | 13
increased circulating creatine... 1 | 5
increased circulating sodium l... 1 | 71
increased mean corpuscular hem... 1 | 36
persistence of hyaloid vascula... 1 | 33
prenatal lethality prior to he... 1 | 87
tremors 1 | 39

Disease

Carcinoma 17 | 11,192
osteosarcoma 13 | 7,766
ovarian cancer 13 | 8,297
lung cancer 10 | 4,607
Kidney cancer 9 | 2,548
Cancer 8 | 2,388
Breast cancer 6 | 3,469
Multiple myeloma 6 | 1,296
astrocytic glioma 6 | 2,530
group 3 medulloblastoma 6 | 4,002
oligodendroglioma 6 | 2,768
Pick disease 5 | 1,856
acute quadriplegic myopathy 5 | 1,133
atypical teratoid / rhabdoid tumor 5 | 4,971
ependymoma 5 | 4,559
glioblastoma 5 | 5,635
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,204
malignant mesothelioma 5 | 3,135
medulloblastoma, large-cell 5 | 6,086
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,911
psoriasis 5 | 6,514
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,872
juvenile dermatomyositis 4 | 1,147
primitive neuroectodermal tumor 4 | 2,957
spina bifida 4 | 1,053
Prostatic Neoplasms 3 | 472
Rheumatoid arthritis 3 | 1,156
Waldenstrons macroglobulinemia 3 | 742
astrocytoma 3 | 1,113
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,902
Alcoholic Intoxication, Chronic 2 | 283
Astrocytoma, Pilocytic 2 | 3,006
Cockayne syndrome 2 | 59
Down syndrome 2 | 480
Mesothelioma, Malignant 2 | 103
diabetes mellitus 2 | 1,683
gastric cancer 2 | 445
medulloblastoma 2 | 702
pediatric high grade glioma 2 | 1,035
pituitary cancer 2 | 1,915
primary pancreatic ductal adenocarcinoma 2 | 1,071
sonic hedgehog group medulloblastoma 2 | 459
subependymal giant cell astrocytoma 2 | 2,230
tuberculosis 2 | 1,963
Adenocarcinoma 1 | 116
Adenoma 1 | 159
Alopecia 1 | 113
Amphetamine-Related Disorders 1 | 72
Astigmatism 1 | 54
Atrophic vaginitis 1 | 14
Bone neoplasms 1 | 6
Brain cancer 1 | 30
Breast Neoplasms 1 | 423
Carcinoma, Non-Small-Cell Lung 1 | 97
Carcinoma, Squamous Cell 1 | 107
Chromosome 18p deletion syndrome 1 | 4
Cocaine-Related Disorders 1 | 90
Colonic Neoplasms 1 | 133
Contraception 1 | 15
Corneal edema 1 | 14
Disseminated intravascular coagulation 1 | 33
Edwards syndrome 1 | 15
Esophageal Neoplasms 1 | 68
Exophthalmos 1 | 110
Gaucher disease type 1 1 | 177
Hypercalcemia 1 | 57
Hyperparathyroidism 1 | 46
Influenza 1 | 136
Keratitis 1 | 60
Keratoconus 1 | 111
Kidney disease 1 | 411
Klinefelter's syndrome 1 | 55
Leukemia, Myeloid 1 | 18
Malignant glioma 1 | 25
Mammary Neoplasms 1 | 403
Menopausal flushing 1 | 17
Metabolic acidosis 1 | 89
Metastatic Breast Carcinoma 1 | 21
Metastatic Prostate Carcinoma 1 | 18
Microcephaly 1 | 166
Myeloid Leukemia 1 | 19
Neurodevelopmental Disorders 1 | 70
Nonsyndromic deafness 1 | 137
Osteoarthritis 1 | 179
Pancytopenia 1 | 45
Patau syndrome 1 | 12
Postmenopausal osteoporosis 1 | 19
Pulmonary hypertension 1 | 85
Sensorineural Hearing Loss (disorder) 1 | 281
Shwachman-Diamond syndrome 1 | 17
Squamous cell carcinoma 1 | 125
Thyroid Neoplasm 1 | 37
Thyroid Neoplasms 1 | 34
Turner syndrome 1 | 24
Wolf-Hirschhorn syndrome 1 | 32
atypical teratoid/rhabdoid tumor 1 | 349
inflammatory breast cancer 1 | 272
non-small cell lung carcinoma 1 | 302
posterior fossa group A ependymoma 1 | 456
tuberculosis and treatment for 6 months 1 | 399

Tissue

Blood and immune system 22 | 16,909
Cardiovascular System 22 | 15,192
Digestive Tract 22 | 17,369
Endocrine System 22 | 18,159
Female tissues 22 | 17,400
Male tissues 22 | 17,142
Nervous System 22 | 16,725
Respiratory system 22 | 16,393
Skin and soft tissues 22 | 17,230
Urinary Tract 22 | 16,678
Liver and Pancreas 21 | 16,750

Target Family

Non-IDG 13 | 12,091
Enzyme 4 | 4,145
Epigenetic 4 | 242
Nuclear Receptor 1 | 48

GO Function

RNA polymerase II core binding 22 | 22
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
DBIRD complex subunit ZNF326 ZNF326 Tbio Non-IDG -0.42207 3.94 120
RNA transcription, translation and transport factor protein RTRAF Tbio Non-IDG -1.06152 12.4 148
RNA polymerase-associated protein CTR9 homolog CTR9 Tbio Enzyme -1.24736 19.1 120
Steroid hormone receptor ERR2 ESRRB Tchem Nuclear Receptor -1.95523 86.9 173
Heterogeneous nuclear ribonucleoprotein U HNRNPU Tbio Non-IDG -2.33813 207.8 169
Pre-mRNA cleavage complex 2 protein Pcf11 PCF11 Tbio Non-IDG -1.38684 23.0 33
ATP-dependent RNA helicase A DHX9 Tbio Enzyme -2.85807 734.3 204
Transcription elongation factor 1 homolog ELOF1 Tdark Non-IDG -0.30103 2.00 59
ATP-dependent DNA helicase Q5 RECQL5 Tbio Enzyme -1.67373 56.2 148
N-lysine methyltransferase SMYD2 SMYD2 Tchem Epigenetic -1.64698 52.7 219