Development Level

Tbio 3 | 11,445
Tdark 2 | 6,588
Tclin 1 | 613

IMPC Phenotype

increased startle reflex 1 | 112

Disease

Carcinoma 6 | 11,493
osteosarcoma 3 | 7,950
Cancer 2 | 2,499
Treacher Collins syndrome 2 | 27
acute quadriplegic myopathy 2 | 1,158
atypical teratoid / rhabdoid tumor 2 | 5,112
invasive ductal carcinoma 2 | 2,951
lung cancer 2 | 4,740
malignant mesothelioma 2 | 3,232
psoriasis 2 | 6,694
Abnormal skeletal development 1 | 60
Abnormality of bone mineral density 1 | 5
Absent eyelashes 1 | 16
Adenocarcinoma 1 | 122
Agenesis of teeth 1 | 21
Alopecia 1 | 115
Animal Mammary Neoplasms 1 | 136
Aplasia of eyelashes 1 | 16
Auricular malformation 1 | 41
Barrett's esophagus 1 | 182
Basal cell carcinoma 1 | 54
Brain disease 1 | 96
Breast Neoplasms 1 | 445
Breast disease 1 | 7
Breast fibroadenoma 1 | 8
Bronchioloalveolar Adenocarcinoma 1 | 14
Carcinogenesis 1 | 8
Carcinoma, Basal Cell 1 | 28
Carcinoma, Ductal, Breast 1 | 11
Carcinoma, Renal Cell 1 | 124
Cholangiocarcinoma 1 | 35
Coloboma of eyelid 1 | 15
Comedo carcinoma 1 | 2
Conductive hearing loss 1 | 123
Craniofacial Abnormalities 1 | 151
Decreased projection of maxilla 1 | 66
Decreased projection of midface 1 | 105
Deficiency of upper jaw bones 1 | 66
Depressed cheekbone 1 | 22
Downward slant of palpebral fissure 1 | 158
Drug psychosis 1 | 7
Esophageal Neoplasms 1 | 69
Exanthem 1 | 37
Failure of development of eyelashes 1 | 16
Flattening of the zygomatic bone 1 | 22
Gallbladder Neoplasms 1 | 10
Gastric Cancer, Hereditary Diffuse 1 | 12
Gastrointestinal Neoplasms 1 | 7
Glioma 1 | 74
Glioma Susceptibility 1 1 | 5
HER2 Positive Carcinoma of Breast 1 | 2
HER2-positive carcinoma of breast 1 | 21
Hypoplasia of the maxilla 1 | 66
Hypoplasia of the zygomatic bone 1 | 22
Hypotrophic cheekbone 1 | 22
Hypotrophic malar bone 1 | 129
Hypotrophic maxilla 1 | 66
Hypotrophic midface 1 | 105
Lobular neoplasia 1 | 15
Lymphatic Metastasis 1 | 15
Malar flattening 1 | 129
Mammary Neoplasms 1 | 425
Mammary Neoplasms, Animal 1 | 136
Mammary Neoplasms, Experimental 1 | 154
Maxillary retrognathia 1 | 66
Midface retrusion 1 | 105
Mucositis 1 | 29
Multiple system atrophy 1 | 29
Narrow internal auditory canal 1 | 8
Neoplasm Metastasis 1 | 168
Neoplasm Recurrence, Local 1 | 37
Neoplasm of stomach 1 | 11
Neoplasms, Experimental 1 | 40
Neutropenia 1 | 72
Non-small cell lung cancer, positive for epidermal growth factor receptor expression 1 | 4
Open Bite 1 | 21
Osteoporosis 1 | 363
Ovarian Neoplasms 1 | 102
Papilloma 1 | 44
Pleomorphic adenoma 1 | 18
REM sleep behavior disorder 1 | 14
Reduced number of teeth 1 | 21
Renal Cell Carcinoma 1 | 214
Retinitis pigmentosa 4 1 | 38
Retrognathia 1 | 54
Retrusion of upper jaw bones 1 | 66
Secondary malignant neoplasm of female breast 1 | 3
Secondary malignant neoplasm of stomach 1 | 2
Simple ear 1 | 41
Small cheekbone 1 | 22
Small midface 1 | 105
Somatic mutation 1 | 61
Stomach Carcinoma 1 | 11
Stomach cancer 1 | 30
Stomatitis 1 | 21
Substance abuse 1 | 59
Tethered spinal cord syndrome 1 | 11
Thrombocytopenia 1 | 197
gallbladder neoplasm 1 | 10
ovarian neoplasm 1 | 99

Tissue

Blood and immune system 5 | 16,909
Cardiovascular System 5 | 15,192
Digestive Tract 5 | 17,369
Endocrine System 5 | 18,159
Female tissues 5 | 17,400
Liver and Pancreas 5 | 16,750
Male tissues 5 | 17,142
Nervous System 5 | 16,725
Respiratory system 5 | 16,393
Skin and soft tissues 5 | 17,230
Urinary Tract 5 | 16,678

Target Family

Non-IDG 4 | 12,091
Enzyme 1 | 4,145
Kinase 1 | 634

GO Function

RNA polymerase I core binding 6 | 6
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Treacle protein TCOF1 Tbio Non-IDG -3.44117 2743.5 131
Putative RRN3-like protein RRN3P1 RRN3P1 Tdark Non-IDG -1.49736 49.0 0
Protein SPT2 homolog SPTY2D1 Tdark Non-IDG -0.67388 4.82 9
Nucleolar and coiled-body phosphoprotein 1 NOLC1 Tbio Non-IDG -1.62313 48.1 216
RNA polymerase I-specific transcription initiation factor RRN3 RRN3 Tbio Enzyme -1.49736 49.0 163
Receptor tyrosine-protein kinase erbB-2 ERBB2 Tclin Kinase -4.28550 20244.6 3859