Development Level

Tbio 19 | 11,445
Tchem 3 | 1,598
Tclin 1 | 613

IMPC Phenotype

decreased startle reflex 2 | 75
abnormal behavior 1 | 298
abnormal bone structure 1 | 187
abnormal retinal inner nuclear... 1 | 8
decreased fasted circulating g... 1 | 65
decreased total retina thickne... 1 | 17
decreased vertical activity 1 | 208
limb grasping 1 | 41
preweaning lethality, incomple... 1 | 499
trunk curl 1 | 16

Disease

Carcinoma 18 | 11,493
ovarian cancer 14 | 8,520
Cancer 13 | 2,499
Breast cancer 10 | 3,578
atypical teratoid / rhabdoid tumor 10 | 5,112
lung cancer 10 | 4,740
malignant mesothelioma 10 | 3,232
medulloblastoma, large-cell 10 | 6,241
osteosarcoma 10 | 7,950
psoriasis 10 | 6,694
glioblastoma 9 | 5,792
non-small cell lung cancer 9 | 2,890
diabetes mellitus 7 | 1,728
group 4 medulloblastoma 7 | 1,855
invasive ductal carcinoma 7 | 2,951
lung adenocarcinoma 7 | 2,716
subependymal giant cell astrocytoma 7 | 2,287
tuberculosis 7 | 2,010
Kidney cancer 6 | 2,613
Waldenstrons macroglobulinemia 6 | 765
colon cancer 6 | 1,478
group 3 medulloblastoma 6 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,291
lung carcinoma 6 | 2,843
Intellectual disability 5 | 1,016
Liver Cirrhosis, Experimental 5 | 769
breast carcinoma 5 | 1,638
interstitial cystitis 5 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
pancreatic cancer 5 | 2,398
pituitary cancer 5 | 1,972
Amyotrophic lateral sclerosis 4 | 451
Astrocytoma, Pilocytic 4 | 3,081
Breast Neoplasms 4 | 445
Craniofacial Abnormalities 4 | 151
Down syndrome 4 | 499
Endometriosis 4 | 540
Epilepsy 4 | 792
Heart disease 4 | 306
Hypertensive disease 4 | 292
Kidney disease 4 | 430
Mammary Neoplasms 4 | 425
Schizophrenia 4 | 1,160
adrenocortical carcinoma 4 | 1,428
adult high grade glioma 4 | 3,801
cystic fibrosis 4 | 1,696
dermatomyositis 4 | 966
ductal carcinoma in situ 4 | 1,745
primitive neuroectodermal tumor 4 | 3,035
ulcerative colitis 4 | 1,819
Arthritis, Juvenile 3 | 126
Asthma 3 | 385
Atherosclerosis 3 | 291
Brain Injuries 3 | 65
Cell Transformation, Neoplastic 3 | 97
Dull intelligence 3 | 645
Hypertension 3 | 396
Juvenile arthritis 3 | 126
Liver disease 3 | 237
Low intelligence 3 | 645
Melanoma 3 | 711
Mental Retardation 3 | 645
Mental deficiency 3 | 645
Obesity 3 | 678
Pick disease 3 | 1,894
Pneumonia 3 | 174
Poor school performance 3 | 645
Pulmonary Fibrosis 3 | 106
Seizures 3 | 596
Stomach Neoplasms 3 | 300
Toxic encephalopathy 3 | 141
Vascular disease 3 | 319
acute myeloid leukemia 3 | 783
acute quadriplegic myopathy 3 | 1,158
aldosterone-producing adenoma 3 | 665
chronic lymphosyte leukemia 3 | 204
ependymoma 3 | 4,679
fibroadenoma 3 | 559
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
Acromegaly 2 | 51
Adenoma 2 | 167
Alzheimer's disease 2 | 658
Arthritis 2 | 290
Atopic dermatitis 2 | 952
Brain Ischemia 2 | 110
Cerebrovascular disease 2 | 238
Eye disease 2 | 62
Inflammatory bowel disease 2 | 151
Pancreatic Neoplasm 2 | 85
Pancreatic Neoplasms 2 | 85
Reperfusion Injury 2 | 86
Status Epilepticus 2 | 98
Strabismus 2 | 270
astrocytoma 2 | 1,146
hepatocellular carcinoma 2 | 547
nephrosclerosis 2 | 333
pediatric high grade glioma 2 | 1,064
progressive supranuclear palsy 2 | 676
pterygium 2 | 76
urothelial carcinoma 2 | 318

Tissue

Digestive Tract 23 | 17,369
Endocrine System 23 | 18,159
Liver and Pancreas 23 | 16,750
Male tissues 23 | 17,142
Nervous System 23 | 16,725
Skin and soft tissues 23 | 17,230
Blood and immune system 22 | 16,909
Female tissues 22 | 17,400
Respiratory system 22 | 16,393
Urinary Tract 22 | 16,678
Cardiovascular System 21 | 15,192

Target Family

Transcription Factor 9 | 1,400
Non-IDG 8 | 12,091
Enzyme 5 | 4,145
Epigenetic 1 | 242

GO Function

R-SMAD binding 23 | 23
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Probable ATP-dependent RNA helicase DDX5 DDX5 Tbio Enzyme -2.08566 121.1 344
Mothers against decapentaplegic homolog 6 SMAD6 Tbio Transcription Factor -2.07569 106.7 450
Paired box protein Pax-6 PAX6 Tbio Transcription Factor -3.16650 1458.6 570
E3 ubiquitin-protein ligase TRIM33 TRIM33 Tbio Epigenetic -3.10754 1197.2 297
Myocardin MYOCD Tbio Non-IDG -2.37801 242.7 84
Ran-binding protein 3 RANBP3 Tbio Non-IDG -1.41852 21.4 158
Menin MEN1 Tchem Non-IDG -3.23460 1803.0 382
Protein TMEPAI PMEPA1 Tbio Non-IDG -1.35527 24.8 90
Ankyrin repeat domain-containing protein 1 ANKRD1 Tbio Non-IDG -1.79794 62.3 159
Zinc finger E-box-binding homeobox 2 ZEB2 Tbio Transcription Factor -2.49656 262.6 474