Development Level

Tbio 3 | 11,445
Tdark 3 | 6,588
Tclin 1 | 613

IMPC Phenotype

abnormal behavior 1 | 298
abnormal locomotor behavior 1 | 24
decreased circulating fructosa... 1 | 30
decreased circulating serum al... 1 | 82
decreased erythrocyte cell num... 1 | 62
decreased hemoglobin content 1 | 68
decreased pulmonary respirator... 1 | 5
hyperactivity 1 | 148
increased circulating alanine ... 1 | 13

Disease

ependymoma 3 | 4,679
Autistic Disorder 2 | 364
Bipolar Disorder 2 | 666
Carcinoma 2 | 11,493
Depressive disorder 2 | 409
Mental Depression 2 | 333
astrocytic glioma 2 | 2,597
group 3 medulloblastoma 2 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
malignant mesothelioma 2 | 3,232
ovarian cancer 2 | 8,520
22q11 Deletion Syndrome 1 | 10
22q11 partial monosomy syndrome 1 | 9
Abnormality of aortic arch 1 | 9
Abnormality of pulmonary valve 1 | 23
Abnormality of the pharynx 1 | 19
Abnormality of the tonsils 1 | 10
Acne 1 | 52
Acquired metabolic disease 1 | 336
Affective Disorders, Psychotic 1 | 6
Agoraphobia 1 | 21
Alcohol dependence 1 | 107
Alcoholism 1 | 45
Anhedonia 1 | 27
Animal Mammary Neoplasms 1 | 136
Arachnodactyly 1 | 49
Atrial Septal Defects 1 | 85
Attention Deficit Disorder with Hyperactivity 1 | 21
Breast Neoplasms 1 | 445
Bulbous nasal tip 1 | 48
CONOTRUNCAL ANOMALY FACE SYNDROME 1 | 9
Calculus in biliary tract 1 | 2
Cannabis use 1 | 6
Carney complex 1 | 25
Chordoid glioma 1 | 4
Chronic otitis media 1 | 52
Cocaine Dependence 1 | 51
Conduct disorder 1 | 33
Conductive hearing loss 1 | 123
Congenital hypoplasia of kidney 1 | 32
Congenital hypoplasia of thymus 1 | 15
Constipation 1 | 181
Convex nasal bridge 1 | 57
Corneal Neovascularization 1 | 13
Dental caries 1 | 164
DiGeorge syndrome 1 | 47
Dyschezia 1 | 135
Dysphasia 1 | 23
Dysseborrheic dermatitis 1 | 13
Eating disorder 1 | 26
Embryotoxon 1 | 28
Fibromyalgia 1 | 19
Gilles de la Tourette syndrome 1 | 47
Hepatolenticular Degeneration 1 | 24
Heroin dependence 1 | 30
Hyperalgesia 1 | 83
Hypernasal voice 1 | 39
Hypocalcemia 1 | 32
Hypoparathyroidism 1 | 41
Hypoplastic lobules 1 | 11
Hypotrophic malar bone 1 | 129
Immunologic Deficiency Syndromes 1 | 113
Impaired T cell function 1 | 14
Leukemia, Myelocytic, Acute 1 | 120
Leukemia, Myeloid, Acute 1 | 105
Malar flattening 1 | 129
Mammary Neoplasms 1 | 425
Mammary Neoplasms, Animal 1 | 136
Marijuana Abuse 1 | 31
Memory Disorders 1 | 40
Mild Mental Retardation 1 | 70
Musculoskeletal Pain 1 | 3
Myalgia 1 | 54
Nasal voice 1 | 39
Neonatal abstinence syndrome 1 | 11
Nicotine dependence 1 | 54
Occipital myelomeningocele 1 | 8
Opiate dependence 1 | 29
Overfolded helix 1 | 24
Pain 1 | 103
Pain agnosia 1 | 104
Panic disorder 1 | 61
Persistant truncus arteriosus 1 | 17
Personality disorder 1 | 25
Pheochromocytoma 1 | 24
Platybasia 1 | 13
Posterior embryotoxon 1 | 28
Prominent nasal bridge 1 | 57
Rotting teeth 1 | 73
Seasonal affective disorder 1 | 28
Seborrheic dermatitis 1 | 31
Shprintzen syndrome 1 | 9
Small thymus 1 | 13
Substance abuse 1 | 59
Tetany 1 | 18
Tetralogy of Fallot 1 | 63
Velocardiofacial syndrome 1 | 46
ear infection chronic 1 | 52
obsessive-compulsive disorder 1 | 61
post-traumatic stress disorder 1 | 40

Tissue

Blood and immune system 7 | 16,909
Cardiovascular System 7 | 15,192
Digestive Tract 7 | 17,369
Endocrine System 7 | 18,159
Female tissues 7 | 17,400
Liver and Pancreas 7 | 16,750
Male tissues 7 | 17,142
Nervous System 7 | 16,725
Respiratory system 7 | 16,393
Skin and soft tissues 7 | 17,230
Urinary Tract 6 | 16,678

Target Family

Enzyme 7 | 4,145

GO Function

O-methyltransferase activity 7 | 7
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Pre-miRNA 5'-monophosphate methyltransferase BCDIN3D Tbio Enzyme -0.29281 2.93 22
Acetylserotonin O-methyltransferase ASMT Tbio Enzyme -2.40166 255.0 111
Catechol O-methyltransferase COMT Tclin Enzyme -3.46304 2976.1 433
N-acetylserotonin O-methyltransferase-like protein ASMTL Tdark Enzyme -0.24873 1.71 154
Catechol O-methyltransferase domain-containing protein 1 COMTD1 Tdark Enzyme -0.46736 2.84 49
Ubiquinone biosynthesis O-methyltransferase, mitochondrial COQ3 Tbio Enzyme -1.31324 21.2 122
Small RNA 2'-O-methyltransferase HENMT1 Tdark Enzyme -0.64836 4.68 36