Development Level

Tbio 17 | 11,445
Tchem 4 | 1,598

IMPC Phenotype

decreased body weight 2 | 161
decreased startle reflex 2 | 75
preweaning lethality, complete... 2 | 979
preweaning lethality, incomple... 2 | 499
abnormal behavior 1 | 298
abnormal eating behavior 1 | 1
abnormal eye anterior chamber ... 1 | 9
abnormal forced expiratory flo... 1 | 1
abnormal radius morphology 1 | 8
abnormal retinal outer nuclear... 1 | 3
abnormal sensory capabilities-... 1 | 8
abnormal vertebrae morphology 1 | 18
abnormal vibrissa morphology 1 | 25
abnormal whole-body plethysmog... 1 | 4
altered righting response 1 | 1
cataract 1 | 92
decreased body temperature 1 | 2
decreased circulating HDL chol... 1 | 68
decreased circulating chloride... 1 | 30
decreased circulating choleste... 1 | 93
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased grip strength 1 | 116
decreased tidal volume 1 | 1
increased blood urea nitrogen ... 1 | 48
increased body weight 1 | 25
increased circulating alkaline... 1 | 122
increased circulating glycerol... 1 | 9
increased circulating iron lev... 1 | 30
increased grip strength 1 | 41
increased leukocyte cell numbe... 1 | 47
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular vol... 1 | 92
increased monocyte cell number 1 | 63
increased or absent threshold ... 1 | 101
increased prepulse inhibition 1 | 32
increased startle reflex 1 | 112
increased vertical activity 1 | 24
short tibia 1 | 97

Disease

Carcinoma 18 | 11,493
psoriasis 15 | 6,694
medulloblastoma, large-cell 13 | 6,241
group 3 medulloblastoma 11 | 4,104
ovarian cancer 11 | 8,520
oligodendroglioma 10 | 2,850
Cancer 9 | 2,499
glioblastoma 9 | 5,792
lung cancer 9 | 4,740
osteosarcoma 9 | 7,950
Astrocytoma, Pilocytic 8 | 3,081
Breast cancer 8 | 3,578
ependymoma 7 | 4,679
primitive neuroectodermal tumor 7 | 3,035
adrenocortical carcinoma 6 | 1,428
adult high grade glioma 6 | 3,801
astrocytic glioma 6 | 2,597
atypical teratoid / rhabdoid tumor 6 | 5,112
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,955
lung carcinoma 6 | 2,843
Breast Neoplasms 5 | 445
Kidney cancer 5 | 2,613
Mammary Neoplasms 5 | 425
astrocytoma 5 | 1,146
malignant mesothelioma 5 | 3,232
pituitary cancer 5 | 1,972
Carcinoma, Pancreatic Ductal 4 | 20
Schizophrenia 4 | 1,160
gastric carcinoma 4 | 807
group 4 medulloblastoma 4 | 1,855
juvenile dermatomyositis 4 | 1,187
subependymal giant cell astrocytoma 4 | 2,287
Adenoid Cystic Carcinoma 3 | 99
Brachydactyly 3 | 156
Carcinoma, Adenoid Cystic 3 | 99
Cataract 3 | 297
Craniofacial Abnormalities 3 | 151
Failure to gain weight 3 | 365
Lens Opacities 3 | 231
Liver Cirrhosis 3 | 181
Liver cancer 3 | 604
Pediatric failure to thrive 3 | 365
Short distal phalanges 3 | 50
Strabismus 3 | 270
Syndactyly 3 | 88
Tetralogy of Fallot 3 | 63
atypical teratoid/rhabdoid tumor 3 | 357
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 510
cystic fibrosis 3 | 1,696
diabetes mellitus 3 | 1,728
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
nasopharyngeal carcinoma 3 | 1,058
non-small cell lung cancer 3 | 2,890
pediatric high grade glioma 3 | 1,064
posterior fossa group B ependymoma 3 | 416
Abnormality of pulmonary valve 2 | 23
Abnormality of the metacarpal bones 2 | 17
Acquired metabolic disease 2 | 336
Alagille syndrome 2 | 15
Alzheimer's disease 2 | 658
Aplasia Cutis Congenita 2 | 14
Bipolar Disorder 2 | 666
Claw hand 2 | 26
Congenital Abnormalities 2 | 11
Congenital Abnormality 2 | 11
Congenital hemivertebra 2 | 25
Congenital scar 2 | 13
Cutis marmorata 2 | 32
Duchenne muscular dystrophy 2 | 601
Endometriosis 2 | 540
Hypertension 2 | 396
Immune system cancer 2 | 140
Liver Cirrhosis, Experimental 2 | 769
Liver disease 2 | 237
Lymphoid leukemia 2 | 160
Melanoma 2 | 711
Multiple myeloma 2 | 1,332
Parkinson's disease 2 | 392
Primary cutaneous T-cell lymphoma 2 | 29
Scoliosis 2 | 44
Skin cancer 2 | 469
Skull defect 2 | 10
Sparse hair 2 | 59
Spondylocostal dysostosis 2 | 12
Syndactyly of fingers 2 | 48
Thin, sparse hair 2 | 59
Ventricular Septal Defects 2 | 119
aldosterone-producing adenoma 2 | 665
colon cancer 2 | 1,478
cutaneous lupus erythematosus 2 | 1,057
dermatomyositis 2 | 966
lung adenocarcinoma 2 | 2,716
pancreatic cancer 2 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
primary pancreatic ductal adenocarcinoma 2 | 1,109
progressive supranuclear palsy 2 | 676
sonic hedgehog group medulloblastoma 2 | 467
tuberculosis 2 | 2,010
ulcerative colitis 2 | 1,819

Tissue

Endocrine System 21 | 18,159
Nervous System 21 | 16,725
Blood and immune system 20 | 16,909
Digestive Tract 20 | 17,369
Female tissues 20 | 17,400
Male tissues 20 | 17,142
Cardiovascular System 19 | 15,192
Liver and Pancreas 19 | 16,750
Respiratory system 19 | 16,393
Skin and soft tissues 19 | 17,230
Urinary Tract 19 | 16,678

Target Family

Non-IDG 15 | 12,091
Enzyme 4 | 4,145
Kinase 1 | 634
Transcription Factor 1 | 1,400

GO Function

Notch binding 21 | 21
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Polypeptide N-acetylgalactosaminyltransferase 11 GALNT11 Tbio Enzyme -0.66996 5.39 88
Delta-like protein 3 DLL3 Tbio Non-IDG -1.68978 48.6 214
Glutathione-specific gamma-glutamylcyclotransferase 1 CHAC1 Tbio Enzyme -1.29114 18.9 179
Contactin-6 CNTN6 Tbio Non-IDG -2.09155 109.6 79
Delta and Notch-like epidermal growth factor-related receptor DNER Tbio Non-IDG -1.65805 49.1 185
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3 KCTD10 Tbio Non-IDG -0.81230 8.68 90
Transcriptional and immune response regulator TCIM Tbio Non-IDG -1.10916 11.6 42
Multiple epidermal growth factor-like domains protein 10 MEGF10 Tbio Non-IDG -1.34196 23.9 42
AP2-associated protein kinase 1 AAK1 Tchem Kinase -1.28486 18.8 271
SNW domain-containing protein 1 SNW1 Tbio Non-IDG -1.59688 46.1 88