Development Level

Tbio 19 | 10,625
Tclin 4 | 602
Tchem 2 | 1,890

IMPC Term

abnormal behavioral response t... 2 | 52
abnormal behavior 1 | 226
abnormal lens morphology 1 | 73
cataract 1 | 26
decreased circulating HDL chol... 1 | 77
decreased circulating chloride... 1 | 32
decreased circulating choleste... 1 | 85
hypoactivity 1 | 89
increased circulating potassiu... 1 | 31
increased circulating sodium l... 1 | 71
preweaning lethality, complete... 1 | 633
preweaning lethality, incomple... 1 | 260
sclerocornea 1 | 2

Disease

ovarian cancer 17 | 8,484
Cancer 14 | 2,346
osteosarcoma 10 | 7,933
glioblastoma 9 | 5,572
psoriasis 9 | 6,685
lung cancer 8 | 4,466
oligodendroglioma 8 | 2,849
Multiple myeloma 6 | 1,327
diabetes mellitus 6 | 1,663
ependymoma 6 | 2,514
medulloblastoma, large-cell 6 | 6,234
Breast cancer 5 | 3,094
astrocytoma 5 | 1,493
atypical teratoid / rhabdoid tumor 5 | 4,369
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,956
primitive neuroectodermal tumor 5 | 3,031
Mammary Neoplasms 4 | 410
dermatomyositis 4 | 933
group 4 medulloblastoma 4 | 1,875
pancreatic cancer 4 | 2,300
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,795
pediatric high grade glioma 4 | 2,712
subependymal giant cell astrocytoma 4 | 2,287
Asthma 3 | 349
Peripheral T-cell lymphoma 3 | 24
Pick disease 3 | 1,893
Primary cutaneous T-cell lymphoma 3 | 24
Rheumatoid Arthritis 3 | 1,160
acute myeloid leukemia 3 | 780
acute quadriplegic myopathy 3 | 1,157
colon cancer 3 | 1,475
cystic fibrosis 3 | 1,665
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,988
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,289
lung adenocarcinoma 3 | 2,713
lung carcinoma 3 | 2,844
malignant mesothelioma 3 | 3,162
non-small cell lung cancer 3 | 2,798
primary pancreatic ductal adenocarcinoma 3 | 1,271
sonic hedgehog group medulloblastoma 3 | 1,482
tuberculosis 3 | 1,557
Arthritis 2 | 248
Atherosclerosis 2 | 275
Barrett's esophagus 2 | 183
Brain Ischemia 2 | 87
Carcinoma 2 | 2,147
Cardiomegaly 2 | 66
Diabetes Mellitus, Non-Insulin-Dependent 2 | 157
Diarrhea 2 | 155
Down syndrome 2 | 548
Endometriosis 2 | 535
Heart Diseases 2 | 42
Inflammatory bowel disease 2 | 142
Leukemia, Myelocytic, Acute 2 | 113
Liver carcinoma 2 | 217
Lung disease 2 | 132
Melanoma 2 | 261
Myocardial Infarction 2 | 126
Neoplasm Metastasis 2 | 138
Prostatic Neoplasms 2 | 471
Renal Cell Carcinoma 2 | 199
Squamous cell carcinoma 2 | 94
Vascular disease 2 | 281
Waldenstrons macroglobulinemia 2 | 765
adult high grade glioma 2 | 2,148
astrocytic glioma 2 | 2,241
esophageal adenocarcinoma 2 | 737
group 3 medulloblastoma 2 | 2,254
medulloblastoma 2 | 1,524
mucosa-associated lymphoid tissue lymphoma 2 | 480
pilocytic astrocytoma 2 | 3,086
posterior fossa group A ependymoma 2 | 1,511
ulcerative colitis 2 | 2,087
Acute kidney injury 1 | 65
Adult T-Cell Lymphoma/Leukemia 1 | 30
Animal Mammary Neoplasms 1 | 136
Arthritis, Experimental 1 | 39
CEROID LIPOFUSCINOSIS, NEURONAL, 6 1 | 7
Chronic Lymphocytic Leukemia 1 | 242
Cleft palate 1 | 125
Diabetes Mellitus, Experimental 1 | 106
Diabetes Mellitus, Insulin-Dependent 1 | 76
Disease of mental health 1 | 22
Dysplastic nevus syndrome 1 | 7
HIV Infections 1 | 100
Head and neck squamous cell carcinoma 1 | 12
Heart failure 1 | 80
Liver disease 1 | 219
Lymphoma 1 | 56
Lymphoma, Follicular 1 | 20
Malignant neoplasm of testis 1 | 5
Mammary Neoplasms, Experimental 1 | 150
Microsatellite Instability 1 | 12
Muscular atrophy 1 | 67
Neoplasm Invasiveness 1 | 127
Osteoarthritis 1 | 96
Primary immunodeficiency disease 1 | 52
Sezary Syndrome 1 | 26
Skin cancer 1 | 37
Trachoma 1 | 5

Tissue

Endocrine System 25 | 18,512
Blood and immune system 24 | 17,995
Cardiovascular System 24 | 17,958
Digestive Tract 24 | 18,473
Female tissues 24 | 18,647
Liver and Pancreas 24 | 18,136
Male tissues 24 | 17,969
Nervous System 24 | 18,561
Respiratory system 24 | 17,484
Skin and soft tissues 24 | 18,115
Urinary Tract 24 | 18,444

Target Family

Non-IDG 15 | 11,971
Epigenetic 4 | 242
Enzyme 3 | 4,146
Transcription Factor 2 | 1,400
Kinase 1 | 634

GO Function

NF-kappaB binding 25 | 25
metal ion binding 1,917 | 1,917
ATP binding 1,467 | 1,467
DNA binding 1,432 | 1,432
zinc ion binding 1,155 | 1,155
poly(A) RNA binding 1,107 | 1,107
transcription factor activity,... 853 | 853
calcium ion binding 695 | 695
G-protein coupled receptor act... 661 | 661
protein homodimerization activ... 569 | 569
RNA binding 445 | 445
olfactory receptor activity 424 | 424
sequence-specific DNA binding 398 | 398
GTP binding 374 | 374
chromatin binding 372 | 372
protein serine/threonine kinas... 336 | 336
RNA polymerase II core promote... 332 | 332
identical protein binding 311 | 311
nucleotide binding 311 | 311
receptor binding 303 | 303
protein kinase binding 289 | 289
enzyme binding 286 | 286
cadherin binding involved in c... 277 | 277
GTPase activator activity 273 | 273
ubiquitin protein ligase bindi... 258 | 258
ubiquitin-protein transferase ... 253 | 253
serine-type endopeptidase acti... 246 | 246
transcription coactivator acti... 241 | 241
transcription factor binding 240 | 240
structural molecule activity 232 | 232
GTPase activity 231 | 231
transcriptional activator acti... 230 | 230
ligase activity 227 | 227
protein heterodimerization act... 227 | 227
structural constituent of ribo... 212 | 212
transcription regulatory regio... 202 | 202
transmembrane signaling recept... 201 | 201
RNA polymerase II regulatory r... 200 | 200
receptor activity 200 | 200
transcription corepressor acti... 198 | 198
magnesium ion binding 197 | 197
signal transducer activity 196 | 196
nucleic acid binding 184 | 184
protein kinase activity 183 | 183
carbohydrate binding 180 | 180
ubiquitin protein ligase activ... 173 | 173
RNA polymerase II transcriptio... 162 | 162
heparin binding 160 | 160
iron ion binding 141 | 141
lipid binding 136 | 136
transporter activity 136 | 136
actin binding 133 | 133
ATPase activity 132 | 132
protein C-terminus binding 129 | 129
heme binding 127 | 127
microtubule binding 123 | 123
protein tyrosine kinase activi... 119 | 119
cytokine activity 118 | 118
Ras guanyl-nucleotide exchange... 113 | 113
mRNA binding 112 | 112
metalloendopeptidase activity 112 | 112
transcriptional repressor acti... 110 | 110
structural constituent of cyto... 108 | 108
Rab GTPase binding 105 | 105
antigen binding 104 | 104
protein domain specific bindin... 102 | 102
peptide antigen binding 101 | 101
guanyl-nucleotide exchange fac... 98 | 98
protein complex binding 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 92 | 92
oxidoreductase activity 91 | 91
transcriptional activator acti... 91 | 91
actin filament binding 89 | 89
hydrolase activity 89 | 89
ion channel binding 89 | 89
protein tyrosine phosphatase a... 88 | 88
electron carrier activity 87 | 87
protease binding 87 | 87
histone binding 86 | 86
integrin binding 83 | 83
growth factor activity 82 | 82
phospholipid binding 82 | 82
single-stranded DNA binding 81 | 81
unfolded protein binding 77 | 77
kinase activity 75 | 75
thiol-dependent ubiquitin-spec... 75 | 75
phosphatidylinositol binding 74 | 74
calmodulin binding 73 | 73
histone deacetylase binding 73 | 73
Rho guanyl-nucleotide exchange... 72 | 72
drug binding 71 | 71
double-stranded DNA binding 70 | 70
peptidase activity 70 | 70
protein N-terminus binding 70 | 70
virus receptor activity 68 | 68
beta-catenin binding 67 | 67
microtubule motor activity 67 | 67
protein transporter activity 67 | 67
calcium channel activity 66 | 66
ubiquitin binding 66 | 66

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Glycogen synthase kinase-3 beta GSK3B Tclin Kinase -2.94349 567.7 767
Forkhead box protein P3 FOXP3 Tbio Transcription Factor -3.60057 5680.3 1162
NF-kappa-B inhibitor alpha NFKBIA Tchem Non-IDG -3.34160 1960.9 1181
B-cell lymphoma/leukemia 10 BCL10 Tbio Non-IDG -0.69461 4.24 679
COMM domain-containing protein 7 COMMD7 Tbio Non-IDG -0.83144 8.79 64
Apoptosis-stimulating of p53 protein 2 TP53BP2 Tbio Non-IDG -1.80161 68.4 178
Hypoxia-inducible factor 1-alpha inhibitor HIF1AN Tbio Non-IDG -1.87551 72.0 389
Copine-1 CPNE1 Tbio Non-IDG -0.65398 5.50 122
FAS-associated factor 1 FAF1 Tbio Non-IDG -1.66741 51.3 183
Histone deacetylase 1 HDAC1 Tclin Epigenetic -2.97422 866.1 1107