Development Level

Tbio 14 | 11,445
Tchem 3 | 1,598

IMPC Phenotype

abnormal behavior 1 | 298
abnormal coat-hair pigmentatio... 1 | 64
embryonic lethality prior to t... 1 | 278
hyperactivity 1 | 148
persistence of hyaloid vascula... 1 | 33
preweaning lethality, complete... 1 | 979

Disease

Carcinoma 13 | 11,493
osteosarcoma 10 | 7,950
glioblastoma 7 | 5,792
ovarian cancer 7 | 8,520
ependymoma 6 | 4,679
medulloblastoma, large-cell 6 | 6,241
adult high grade glioma 5 | 3,801
atypical teratoid / rhabdoid tumor 5 | 5,112
lung carcinoma 4 | 2,843
Kidney cancer 3 | 2,613
Pick disease 3 | 1,894
cystic fibrosis 3 | 1,696
group 3 medulloblastoma 3 | 4,104
lung cancer 3 | 4,740
malignant mesothelioma 3 | 3,232
psoriasis 3 | 6,694
Astrocytoma, Pilocytic 2 | 3,081
Bipolar Disorder 2 | 666
Breast cancer 2 | 3,578
Cancer 2 | 2,499
Leukemia 2 | 104
Retinitis Pigmentosa 2 | 226
Sengers syndrome 2 | 18
astrocytoma 2 | 1,146
cone-rod dystrophy 2 | 59
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
non-small cell lung cancer 2 | 2,890
oligodendroglioma 2 | 2,850
pancreatic cancer 2 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
pediatric high grade glioma 2 | 1,064
posterior fossa group B ependymoma 2 | 416
primary pancreatic ductal adenocarcinoma 2 | 1,109
primitive neuroectodermal tumor 2 | 3,035
sonic hedgehog group medulloblastoma 2 | 467
tuberculosis 2 | 2,010
ulcerative colitis 2 | 1,819
3-methylglutaconic aciduria 1 | 29
Acquired immunodeficiency syndrome 1 | 197
Acquired metabolic disease 1 | 336
Acute kidney injury 1 | 70
Barth syndrome 1 | 23
COPD 1 | 118
Cardiomyopathy 1 | 116
Cardiovascular system disease 1 | 246
Cone dystrophy 1 | 71
Depressive disorder 1 | 409
Diabetic Nephropathies 1 | 37
Diabetic Nephropathy 1 | 34
Early myoclonic encephalopathy 1 | 15
Fibrosis 1 | 44
Fundus dystrophy 1 | 83
Hemolytic-Uremic Syndrome 1 | 30
Hypertrophic Cardiomyopathy 1 | 117
Hypospadias 1 | 53
Infarction, Middle Cerebral Artery 1 | 33
Liver Cirrhosis, Experimental 1 | 769
Liver cancer 1 | 604
Lymphopenia 1 | 67
MYELODYSPLASTIC SYNDROME 1 | 53
Melanoma 1 | 711
Memory Disorders 1 | 40
Mental Depression 1 | 333
Mood instability 1 | 2
Multiple Sclerosis 1 | 540
Myelodysplastic Syndromes 1 | 26
Myocardial Infarction 1 | 151
Nephrolithiasis 1 | 56
Nephrotic Syndrome 1 | 78
Osteoporosis 1 | 363
Parkinson's disease 1 | 392
Progressive disorder 1 | 142
Proteinuria 1 | 144
Schizophrenia 1 | 1,160
Sjogren's syndrome 1 | 26
Skin cancer 1 | 469
Thickening of glomerular basement membrane 1 | 7
Thrombocytopenia 1 | 197
Type 2 diabetes mellitus 1 | 272
Unipolar Depression 1 | 250
Waldenstrons macroglobulinemia 1 | 765
active Crohn's disease 1 | 922
adrenocortical carcinoma 1 | 1,428
aldosterone-producing adenoma 1 | 665
atypical teratoid/rhabdoid tumor 1 | 357
axial spondyloarthropathy 1 | 28
esophageal adenocarcinoma 1 | 737
extra-adrenal pheochromocytoma 1 | 7
gastric carcinoma 1 | 807
intraductal papillary-mucinous carcinoma (IPMC) 1 | 2,989
juvenile dermatomyositis 1 | 1,187
medulloblastoma 1 | 720
non diabetic and post-ischemic heart failure 1 | 200
obsessive-compulsive disorder 1 | 61
pituitary cancer 1 | 1,972
progressive supranuclear palsy 1 | 676
spina bifida 1 | 1,074
subependymal giant cell astrocytoma 1 | 2,287
tuberculosis and treatment for 6 months 1 | 409

Tissue

Endocrine System 17 | 18,159
Male tissues 17 | 17,142
Nervous System 17 | 16,725
Cardiovascular System 16 | 15,192
Digestive Tract 16 | 17,369
Female tissues 16 | 17,400
Liver and Pancreas 16 | 16,750
Respiratory system 16 | 16,393
Skin and soft tissues 16 | 17,230
Urinary Tract 16 | 16,678
Blood and immune system 14 | 16,909

Target Family

Enzyme 9 | 4,145
Kinase 8 | 634

GO Function

NAD+ kinase activity 17 | 17
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Diacylglycerol kinase eta DGKH Tbio Kinase -1.45863 29.5 92
Diacylglycerol kinase beta DGKB Tbio Enzyme -1.47875 33.8 128
Diacylglycerol kinase theta DGKQ Tbio Kinase -1.58632 35.6 169
Diacylglycerol kinase epsilon DGKE Tbio Enzyme -1.62076 41.9 159
NAD kinase 2, mitochondrial NADK2 Tbio Kinase -0.81808 8.08 110
Diacylglycerol kinase delta DGKD Tbio Enzyme -1.41858 27.5 133
Diacylglycerol kinase kappa DGKK Tbio Enzyme 0.00000 88
Diacylglycerol kinase iota DGKI Tbio Enzyme -0.89505 7.70 152
Ceramide kinase CERK Tchem Kinase -1.84215 79.4 229
NAD kinase NADK Tbio Kinase -1.49880 29.8 98