Development Level

Tbio 8 | 11,445
Tdark 2 | 6,588

IMPC Phenotype

decreased body weight 1 | 161
decreased circulating LDL chol... 1 | 38
decreased circulating alanine ... 1 | 47
decreased circulating choleste... 1 | 93
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased total body fat amoun... 1 | 207
preweaning lethality, complete... 1 | 979

Disease

ovarian cancer 6 | 8,520
osteosarcoma 5 | 7,950
Carcinoma 4 | 11,493
psoriasis 3 | 6,694
Broad flat nasal bridge 2 | 236
Cancer 2 | 2,499
Chlamydia 2 | 21
Coarse facial features 2 | 108
Cognitive delay 2 | 608
Concave bridge of nose 2 | 195
Congenital deafness 2 | 185
Cryptorchidism 2 | 296
Deafness 2 | 198
Dental abnormalities 2 | 60
Depressed nasal bridge 2 | 195
Depressed nasal root/bridge 2 | 195
Dull intelligence 2 | 645
Epilepsy 2 | 792
Global developmental delay 2 | 608
Hearing Loss, Partial 2 | 185
Intellectual disability 2 | 1,016
Long eyelashes 2 | 37
Low intelligence 2 | 645
Mental Retardation 2 | 645
Mental and motor retardation 2 | 608
Mental deficiency 2 | 645
Muscle hypotonia 2 | 571
Nasal bridge wide 2 | 236
Poor school performance 2 | 645
Roberts syndrome 2 | 15
Seizures 2 | 596
Short stature 2 | 531
Small head 2 | 374
Thickened facial skin with coarse facial features 2 | 108
Tooth Abnormalities 2 | 69
active Crohn's disease 2 | 922
colon cancer 2 | 1,478
glioblastoma 2 | 5,792
group 3 medulloblastoma 2 | 4,104
hearing impairment 2 | 199
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
lung cancer 2 | 4,740
medulloblastoma, large-cell 2 | 6,241
non primary Sjogren syndrome sicca 2 | 891
pituitary cancer 2 | 1,972
Ascariasis 1 | 7
Auricular malformation 1 | 41
Bushy eyebrows 1 | 49
Cholera 1 | 34
Cleft palate with cleft lip 1 | 23
Coloboma of optic disc 1 | 9
Congenital Camptodactyly 1 | 40
Congenital hypoplasia of kidney 1 | 32
Contracture of joint of hand 1 | 30
Deep philtrum 1 | 21
Depressed philtrum 1 | 21
Dilatation of ureter 1 | 15
Epidermolysis bullosa 1 | 21
Full lower lip 1 | 64
Fundus coloboma 1 | 18
Generalized hirsutism 1 | 36
Hypertrichosis 1 | 46
Ichthyosis bullosa of Siemens 1 | 5
Inadequate arch length for tooth size 1 | 45
Kidney Neoplasms 1 | 37
Kindler syndrome 1 | 11
Kyphoscoliosis deformity of spine 1 | 60
Meningioma 1 | 41
Microphthalmia 1 | 76
Nail disease 1 | 9
Narrow thorax 1 | 53
Neurilemmoma 1 | 23
Oculodentodigital dysplasia 1 | 14
Oral cleft 1 | 18
Overfolded helix 1 | 24
Patella aplasia-hypoplasia 1 | 12
Pelvic inflammatory disease 1 | 21
Prominent lower lip 1 | 64
Pulmonary artery stenosis 1 | 22
Rectal prolapse 1 | 19
Recurrent infections 1 | 48
Recurrent otitis media 1 | 42
Retinoblastoma 1 | 19
Self Mutilation 1 | 14
Short distal phalanges 1 | 50
Simple ear 1 | 41
Sloping shoulders 1 | 21
Sparse eyebrow 1 | 42
Syndactyly of fingers 1 | 48
Tachycardia, Ventricular 1 | 22
Thin upper lip vermilion 1 | 67
Tooth Crowding 1 | 45
Tooth mass arch size discrepancy 1 | 45
Tooth size discrepancy 1 | 45
Torsades de Pointes 1 | 8
Type 1 diabetes mellitus 1 | 109
Uroureter 1 | 15
X- linked recessive 1 | 110
X-linked dominant 1 | 57
non-small cell lung carcinoma 1 | 317

Tissue

Blood and immune system 9 | 16,909
Digestive Tract 9 | 17,369
Endocrine System 9 | 18,159
Female tissues 9 | 17,400
Liver and Pancreas 9 | 16,750
Male tissues 9 | 17,142
Nervous System 9 | 16,725
Skin and soft tissues 9 | 17,230
Cardiovascular System 8 | 15,192
Respiratory system 8 | 16,393
Urinary Tract 8 | 16,678

Target Family

Enzyme 9 | 4,145
Transcription Factor 1 | 1,400

GO Function

N-acetyltransferase activity 10 | 10
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
N-acetyltransferase ESCO1 ESCO1 Tbio Enzyme -1.65145 44.6 49
N-acetyltransferase 14 NAT14 Tbio Enzyme -1.00750 8.01 80
N-acetyltransferase 6 NAT6 Tbio Enzyme -0.84731 6.93 153
N-acetyltransferase ESCO2 ESCO2 Tbio Enzyme -2.41255 257.2 66
RNA cytidine acetyltransferase NAT10 Tbio Enzyme -1.79762 61.5 125
N-acetyltransferase 9 NAT9 Tdark Enzyme -3.02820 1070.9 44
N-alpha-acetyltransferase 10 NAA10 Tbio Enzyme -2.42216 249.3 108
Putative N-acetyltransferase 8B NAT8B Tbio Enzyme 0.00000 0
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 SMARCE1 Tbio Transcription Factor -1.51153 35.7 270
Probable N-acetyltransferase 16 NAT16 Tdark Enzyme -0.51188 3.25 11