Development Level

Tbio 13 | 10,625
Tchem 1 | 1,890

Disease

Narcolepsy 7 | 69
breast carcinoma 7 | 1,614
diabetes mellitus 7 | 1,663
lung carcinoma 7 | 2,844
Rheumatoid Arthritis 6 | 1,170
glioblastoma 6 | 5,572
lung cancer 6 | 4,473
non-small cell lung cancer 6 | 2,798
primary Sjogren syndrome 6 | 788
Berylliosis 5 | 28
Multiple Sclerosis, Susceptibility to 5 | 15
Narcolepsy-cataplexy 5 | 21
active Crohn's disease 5 | 918
invasive ductal carcinoma 5 | 2,950
ovarian cancer 5 | 8,491
pilocytic astrocytoma 5 | 3,086
systemic lupus erythematosus 5 | 172
Diffuse cutaneous systemic sclerosis 4 | 17
Duchenne muscular dystrophy 4 | 602
Hepatitis B, Chronic 4 | 15
Multiple Sclerosis 4 | 498
Rheumatoid Arthritis, Systemic Juvenile 4 | 16
Sarcoidosis 1 4 | 14
adult high grade glioma 4 | 2,148
follicular lymphoma 4 | 17
interstitial cystitis 4 | 2,299
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,988
limited scleroderma 4 | 19
primary pancreatic ductal adenocarcinoma 4 | 1,271
sarcoidosis 4 | 368
subependymal giant cell astrocytoma 4 | 2,287
Asthma 3 | 349
Celiac disease 3 | 112
Diabetes Mellitus, Insulin-Dependent 3 | 77
Hypersensitivity reaction type II disease 3 | 235
Juvenile rheumatoid arthritis 3 | 105
Systemic scleroderma 3 | 66
Type 1 diabetes mellitus 3 | 104
Waldenstrons macroglobulinemia 3 | 764
active ulcerative colitis 3 | 477
adrenocortical carcinoma 3 | 1,427
astrocytoma 3 | 1,493
cutaneous lupus erythematosus 3 | 1,056
cystic fibrosis 3 | 1,670
dermatomyositis 3 | 966
ductal carcinoma in situ 3 | 1,745
esophageal adenocarcinoma 3 | 737
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,956
juvenile dermatomyositis 3 | 1,189
limb girdle muscular dystrophy 2I 3 | 56
medulloblastoma, large-cell 3 | 6,234
pancreatic cancer 3 | 2,300
posterior fossa group A ependymoma 3 | 1,511
psoriasis 3 | 6,685
tuberculosis 3 | 1,563
ulcerative colitis 3 | 2,087
Achalasia, Familial Esophageal 2 | 3
Addison's disease 2 | 29
Autoimmune thyroiditis 2 | 24
Barrett's esophagus 2 | 185
Becker muscular dystrophy 2 | 187
Breast cancer 2 | 3,098
Celiac Disease, Susceptibility To, 1 2 | 2
Collagen disease 2 | 25
Down syndrome 2 | 548
Esophageal Achalasia 2 | 2
Geographic tongue 2 | 5
Graves' disease 2 | 25
Hypersensitivity 2 | 63
Kleine-Levin syndrome 2 | 5
Lupus Erythematosus, Systemic 2 | 73
Oropharynx cancer 2 | 9
Primary achalasia 2 | 3
atypical teratoid / rhabdoid tumor 2 | 4,369
colon cancer 2 | 1,475
group 4 medulloblastoma 2 | 1,875
head and neck cancer and chronic obstructive pulmonary disease 2 | 237
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,289
lung adenocarcinoma 2 | 2,714
malignant mesothelioma 2 | 3,163
membranous glomerulonephritis 2 | 12
nephrosclerosis 2 | 329
osteosarcoma 2 | 7,933
pancreatic carcinoma 2 | 567
type I diabetes mellitus 2 | 22
Alopecia universalis 1 | 10
Atopic dermatitis 1 | 944
Cancer 1 | 2,346
Chronic obstructive pulmonary disease 1 | 147
Coronary artery disease 1 | 240
Dermatitis 1 | 141
Drug Eruptions 1 | 18
Heart disease 1 | 279
Hepatitis B 1 | 103
IGA Glomerulonephritis 1 | 454
Proteinuria 1 | 63
Urticaria 1 | 53
Vasculitis 1 | 64
atypical teratoid/rhabdoid tumor 1 | 1,095
tuberculosis and treatment for 3 months 1 | 327

Tissue

Blood and immune system 10 | 17,994
Digestive Tract 10 | 18,472
Endocrine System 10 | 18,511
Female tissues 10 | 18,646
Liver and Pancreas 10 | 18,135
Male tissues 10 | 17,968
Nervous System 10 | 18,560
Respiratory system 10 | 17,483
Urinary Tract 10 | 18,443
Cardiovascular System 9 | 17,957
Skin and soft tissues 8 | 18,114

Target Family

Non-IDG 14 | 11,969

GO Function

MHC class II receptor activity 14 | 14
metal ion binding 1,917 | 1,917
ATP binding 1,467 | 1,467
DNA binding 1,432 | 1,432
zinc ion binding 1,155 | 1,155
poly(A) RNA binding 1,107 | 1,107
transcription factor activity,... 853 | 853
calcium ion binding 695 | 695
G-protein coupled receptor act... 661 | 661
protein homodimerization activ... 569 | 569
RNA binding 445 | 445
olfactory receptor activity 424 | 424
sequence-specific DNA binding 398 | 398
GTP binding 374 | 374
chromatin binding 372 | 372
protein serine-threonine kinas... 336 | 336
RNA polymerase II core promote... 332 | 332
identical protein binding 311 | 311
nucleotide binding 311 | 311
receptor binding 303 | 303
protein kinase binding 289 | 289
enzyme binding 286 | 286
cadherin binding involved in c... 277 | 277
GTPase activator activity 273 | 273
ubiquitin protein ligase bindi... 258 | 258
ubiquitin-protein transferase ... 253 | 253
serine-type endopeptidase acti... 246 | 246
transcription coactivator acti... 241 | 241
transcription factor binding 240 | 240
structural molecule activity 232 | 232
GTPase activity 231 | 231
transcriptional activator acti... 230 | 230
ligase activity 227 | 227
protein heterodimerization act... 227 | 227
structural constituent of ribo... 212 | 212
transcription regulatory regio... 202 | 202
transmembrane signaling recept... 201 | 201
RNA polymerase II regulatory r... 200 | 200
receptor activity 200 | 200
transcription corepressor acti... 198 | 198
magnesium ion binding 197 | 197
signal transducer activity 196 | 196
nucleic acid binding 184 | 184
protein kinase activity 183 | 183
carbohydrate binding 180 | 180
ubiquitin protein ligase activ... 173 | 173
RNA polymerase II transcriptio... 162 | 162
heparin binding 160 | 160
iron ion binding 141 | 141
lipid binding 136 | 136
transporter activity 136 | 136
actin binding 133 | 133
ATPase activity 132 | 132
protein C-terminus binding 129 | 129
heme binding 127 | 127
microtubule binding 123 | 123
protein tyrosine kinase activi... 119 | 119
cytokine activity 118 | 118
Ras guanyl-nucleotide exchange... 113 | 113
mRNA binding 112 | 112
metalloendopeptidase activity 112 | 112
transcriptional repressor acti... 110 | 110
structural constituent of cyto... 108 | 108
Rab GTPase binding 105 | 105
antigen binding 104 | 104
protein domain specific bindin... 102 | 102
peptide antigen binding 101 | 101
guanyl-nucleotide exchange fac... 98 | 98
protein complex binding 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 92 | 92
oxidoreductase activity 91 | 91
transcriptional activator acti... 91 | 91
actin filament binding 89 | 89
hydrolase activity 89 | 89
ion channel binding 89 | 89
protein tyrosine phosphatase a... 88 | 88
electron carrier activity 87 | 87
protease binding 87 | 87
histone binding 86 | 86
integrin binding 83 | 83
growth factor activity 82 | 82
phospholipid binding 82 | 82
single-stranded DNA binding 81 | 81
unfolded protein binding 77 | 77
kinase activity 75 | 75
thiol-dependent ubiquitin-spec... 75 | 75
phosphatidylinositol binding 74 | 74
calmodulin binding 73 | 73
histone deacetylase binding 73 | 73
Rho guanyl-nucleotide exchange... 72 | 72
drug binding 71 | 71
double-stranded DNA binding 70 | 70
peptidase activity 70 | 70
protein N-terminus binding 70 | 70
virus receptor activity 68 | 68
beta-catenin binding 67 | 67
microtubule motor activity 67 | 67
protein transporter activity 67 | 67
calcium channel activity 66 | 66
ubiquitin binding 66 | 66

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