Development Level

Tbio 6 | 11,445
Tclin 1 | 613

IMPC Phenotype

abnormal lens morphology 1 | 81
cataract 1 | 92
increased fasted circulating g... 1 | 76
preweaning lethality, complete... 1 | 979

Disease

Carcinoma 6 | 11,493
medulloblastoma, large-cell 5 | 6,241
osteosarcoma 5 | 7,950
ovarian cancer 5 | 8,520
Cancer 4 | 2,499
glioblastoma 4 | 5,792
lung cancer 4 | 4,740
psoriasis 4 | 6,694
Lung Neoplasms 3 | 232
atypical teratoid / rhabdoid tumor 3 | 5,112
group 3 medulloblastoma 3 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
malignant mesothelioma 3 | 3,232
non-small cell lung cancer 3 | 2,890
primitive neuroectodermal tumor 3 | 3,035
Adenocarcinoma 2 | 122
Breast Neoplasms 2 | 445
Breast cancer 2 | 3,578
Carcinoma, Squamous Cell 2 | 110
Dry skin 2 | 75
Freckles 2 | 33
Inflammation 2 | 120
Liver neoplasms 2 | 130
Lymphoid leukemia 2 | 160
Melanocytic nevus 2 | 43
Melanoma 2 | 711
Neoplasms 2 | 63
Pancreatic Neoplasm 2 | 85
Pancreatic Neoplasms 2 | 85
Pick disease 2 | 1,894
Skin cancer 2 | 469
Squamous cell carcinoma 2 | 129
Xerosis 2 | 75
adrenocortical carcinoma 2 | 1,428
adult high grade glioma 2 | 3,801
astrocytoma 2 | 1,146
atypical teratoid/rhabdoid tumor 2 | 357
breast carcinoma 2 | 1,638
cutaneous lupus erythematosus 2 | 1,057
diabetes mellitus 2 | 1,728
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
lung adenocarcinoma 2 | 2,716
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
Abnormality of the clitoris 1 | 3
Abnormality of the nasopharynx 1 | 9
Absence of Stensen duct 1 | 4
Absent scalp hair 1 | 5
Acute Kidney Tubular Necrosis 1 | 6
Agenesis of parotid duct 1 | 4
Agenesis of punctum lacrimale 1 | 4
Anhydrotic Ectodermal Dysplasias 1 | 2
Ankyloblepharon 1 | 4
Ankyloblepharon filiforme adnatum 1 | 4
Aplasia/Hypoplasia involving the metacarpal bones 1 | 5
Brain Stem Neoplasms 1 | 4
Cervicitis 1 | 6
Congenital Foot Deformity 1 | 4
Congenital Hand Deformities 1 | 8
Congenital neurologic anomalies 1 | 20
Cutaneous Melanoma 1 | 3
Diabetic dyslipidemia associated with type 2 diabetes mellitus 1 | 2
Duplicated collecting system 1 | 7
Dystrophic toenail changes 1 | 12
Eczema 1 | 45
Encephalomyelitis, Autoimmune, Experimental 1 | 8
Epispadias, male (disorder) 1 | 4
Experimental Autoimmune Encephalomyelitis 1 | 7
Familial hypercholesterolemia - heterozygous 1 | 6
Fingernail dysplasia 1 | 6
Fingerprints, Absence of 1 | 4
Foot Deformities, Congenital 1 | 4
Hand Deformities, Congenital 1 | 8
Hyperconvex fingernails 1 | 7
Hyperlipidemias 1 | 17
Hypoalphalipoproteinemia 1 | 3
Kidney Tubular Necrosis, Acute 1 | 4
Lacrimal Puncta, Absence of 1 | 4
Lacrimation abnormality 1 | 4
Loss of scalp hair 1 | 5
Melanoma, Cutaneous Malignant 1 | 4
Melanoma, Cutaneous Malignant, Susceptibility To, 2 1 | 2
Melanoma-Astrocytoma Syndrome 1 | 2
Melanoma-Pancreatic Cancer Syndrome 1 | 2
Mixed hyperlipidemia 1 | 5
Myeloma, Multiple 1 | 6
Neoplasms, Squamous Cell 1 | 3
Non-midline cleft lip 1 | 6
Oligodactyly 1 | 6
Oval face 1 | 5
Patchy alopecia 1 | 5
Pili canaliculi 1 | 4
Rhabdomyosarcoma, Alveolar 1 | 4
Split hand-foot malformation 1 | 18
Squamous Cell Neoplasms 1 | 3
Urethral atresia 1 | 4
Urinary system cancer 1 | 4
Velopharyngeal Insufficiency 1 | 8
Velopharyngeal dysfunction 1 | 8
pancreatic ductal carcinoma 1 | 11
skin melanoma 1 | 14

Tissue

Blood and immune system 7 | 16,909
Digestive Tract 7 | 17,369
Endocrine System 7 | 18,159
Female tissues 7 | 17,400
Liver and Pancreas 7 | 16,750
Male tissues 7 | 17,142
Nervous System 7 | 16,725
Respiratory system 7 | 16,393
Skin and soft tissues 7 | 17,230
Urinary Tract 7 | 16,678
Cardiovascular System 5 | 15,192

Target Family

Non-IDG 3 | 12,091
Transcription Factor 2 | 1,400
Enzyme 1 | 4,145
Nuclear Receptor 1 | 48

GO Function

MDM2-MDM4 family protein bindi... 7 | 7
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Peroxisome proliferator-activated receptor alpha PPARA Tclin Nuclear Receptor -3.37176 2457.9 501
Tumor protein 63 TP63 Tbio Transcription Factor -3.07398 1154.1 448
Tumor protein p73 TP73 Tbio Transcription Factor -1.92832 82.6 708
Proteasome activator complex subunit 3 PSME3 Tbio Non-IDG -1.87037 83.7 245
E3 ubiquitin-protein ligase RFWD3 RFWD3 Tbio Enzyme -0.67619 6.67 73
CDK5 regulatory subunit-associated protein 3 CDK5RAP3 Tbio Non-IDG -1.31044 22.6 145
Tumor suppressor ARF CDKN2A Tbio Non-IDG -3.72848 9058.6 1063