Development Level

Tchem 9 | 1,598
Tbio 2 | 11,445

Collection

Kinase: IDG Consortium (Target... 2 | 125

IMPC Phenotype

preweaning lethality, complete... 2 | 979
abnormal behavioral response t... 1 | 66
increased or absent threshold ... 1 | 101

Disease

Carcinoma 7 | 11,493
psoriasis 6 | 6,694
Cancer 5 | 2,499
atypical teratoid / rhabdoid tumor 5 | 5,112
glioblastoma 5 | 5,792
osteosarcoma 5 | 7,950
Cardiomyopathies 4 | 110
ependymoma 4 | 4,679
group 3 medulloblastoma 4 | 4,104
lung cancer 4 | 4,740
medulloblastoma, large-cell 4 | 6,241
Arthritis 3 | 290
Astrocytoma, Pilocytic 3 | 3,081
Hyperalgesia 3 | 83
Lung Neoplasms 3 | 232
Schizophrenia 3 | 1,160
Vascular disease 3 | 319
adult high grade glioma 3 | 3,801
ovarian cancer 3 | 8,520
primitive neuroectodermal tumor 3 | 3,035
Alzheimer's disease 2 | 658
Brain Ischemia 2 | 110
CEROID LIPOFUSCINOSIS, NEURONAL, 6 2 | 6
Carcinoma, Squamous Cell 2 | 110
Cholestasis 2 | 155
Cholestasis, Extrahepatic 2 | 25
Cocaine-Related Disorders 2 | 92
Disease Models, Animal 2 | 155
Female infertility 2 | 30
Gastrointestinal system disease 2 | 54
Gliosis 2 | 56
Head and Neck Neoplasms 2 | 26
Hypertrophy 2 | 17
Infertility, Female 2 | 28
Kidney Neoplasm 2 | 29
Kidney Neoplasms 2 | 37
Liver Neoplasms, Experimental 2 | 59
Lung disease 2 | 142
Multiple Sclerosis 2 | 540
Neoplasm Invasiveness 2 | 161
Neoplasm Metastasis 2 | 168
Nerve Degeneration 2 | 121
Ovarian Neoplasms 2 | 102
Parkinson's disease 2 | 392
Pick disease 2 | 1,894
Pneumonia, Pneumococcal 2 | 6
Radiation Injuries, Experimental 2 | 11
Sepsis 2 | 24
Squamous cell carcinoma 2 | 129
Stomach Neoplasms 2 | 300
Streptococcal pneumonia 2 | 6
Substance Withdrawal Syndrome 2 | 55
Trigeminal Neuralgia 2 | 24
adrenocortical carcinoma 2 | 1,428
juvenile dermatomyositis 2 | 1,187
ovarian neoplasm 2 | 99
posterior fossa group A ependymoma 2 | 468
Abnormality of earlobe 1 | 5
Acquired flat foot 1 | 72
Acquired immunodeficiency syndrome 1 | 197
Amyotrophic lateral sclerosis 1 | 451
Atherosclerosis 1 | 291
Atrophic 1 | 10
Atrophy 1 | 10
Bilateral fifth finger clinodactyly 1 | 110
Bladder Neoplasm 1 | 112
Brain disease 1 | 96
Carcinoma of thyroid 1 | 17
Curvature of little finger 1 | 110
Enophthalmos 1 | 75
Eye disease 1 | 62
Flatfoot 1 | 73
Gaucher disease type 1 1 | 180
Heart disease 1 | 306
Hyperglycemia 1 | 137
Hyperplasia 1 | 27
Kidney disease 1 | 430
Language Disorders 1 | 13
Liver cell carcinoma 1 | 15
Liver neoplasms 1 | 130
Lyme disease 1 | 26
Marijuana Abuse 1 | 31
Neurodegenerative disease 1 | 414
Pointed chin 1 | 33
Premature Birth 1 | 77
Premature birth of newborn 1 | 67
Renal Cell Carcinoma 1 | 214
Sezary Syndrome 1 | 27
Sleeping sickness 1 | 37
Smooth philtrum 1 | 43
Sunken eyes 1 | 63
Thin upper lip vermilion 1 | 67
Toxic encephalopathy 1 | 141
Urinary Bladder Neoplasms 1 | 114
atypical teratoid/rhabdoid tumor 1 | 357
axial spondyloarthropathy 1 | 28
breast carcinoma 1 | 1,638
medulloblastoma 1 | 720
tuberculosis 1 | 2,010
tuberculosis and treatment for 6 months 1 | 409

Tissue

Blood and immune system 11 | 16,909
Cardiovascular System 11 | 15,192
Digestive Tract 11 | 17,369
Endocrine System 11 | 18,159
Female tissues 11 | 17,400
Liver and Pancreas 11 | 16,750
Male tissues 11 | 17,142
Nervous System 11 | 16,725
Respiratory system 11 | 16,393
Skin and soft tissues 11 | 17,230
Urinary Tract 11 | 16,678

Target Family

Kinase 11 | 634

GO Function

MAP kinase activity 11 | 11
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Mitogen-activated protein kinase 12 MAPK12 Tchem Kinase -1.95173 88.4 378
Mitogen-activated protein kinase 1 MAPK1 Tchem Kinase -3.18822 1239.4 1248
Mitogen-activated protein kinase 3 MAPK3 Tchem Kinase -3.66226 3484.0 1440
Mitogen-activated protein kinase 13 MAPK13 Tchem Kinase -2.63128 394.0 648
Mitogen-activated protein kinase 7 MAPK7 Tchem Kinase -2.48754 340.0 422
Serine/threonine-protein kinase NLK NLK Tchem Kinase -1.70289 58.7 279
Mitogen-activated protein kinase 14 MAPK14 Tchem Kinase -3.36007 2240.8 1574
Mitogen-activated protein kinase 15 MAPK15 Tchem Kinase -1.49458 34.5 268
Mitogen-activated protein kinase 6 MAPK6 Tbio Kinase -1.64918 41.9 360
Mitogen-activated protein kinase 4 MAPK4 Tbio Kinase -1.21734 13.8 276