Development Level

Tbio 6 | 11,445
Tchem 1 | 1,598

IMPC Phenotype

abnormal behavior 1 | 298
abnormal cornea morphology 1 | 31
abnormal cranium morphology 1 | 36
abnormal eye morphology 1 | 68
abnormal eye pigmentation 1 | 3
abnormal eye size 1 | 7
abnormal eyelid aperture 1 | 2
abnormal iris morphology 1 | 13
abnormal maxilla morphology 1 | 17
abnormal tooth morphology 1 | 24
corneal opacity 1 | 32
corneal vascularization 1 | 6
decreased body length 1 | 101
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased hemoglobin content 1 | 68
decreased lean body mass 1 | 135
eyelids fail to open 1 | 3
preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 6 | 11,493
osteosarcoma 5 | 7,950
glioblastoma 4 | 5,792
invasive ductal carcinoma 4 | 2,951
psoriasis 4 | 6,694
Astrocytoma, Pilocytic 3 | 3,081
Kidney cancer 3 | 2,613
atypical teratoid / rhabdoid tumor 3 | 5,112
ependymoma 3 | 4,679
Pick disease 2 | 1,894
acute myeloid leukemia 2 | 783
astrocytic glioma 2 | 2,597
astrocytoma 2 | 1,146
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
lung adenocarcinoma 2 | 2,716
lung carcinoma 2 | 2,843
malignant mesothelioma 2 | 3,232
medulloblastoma, large-cell 2 | 6,241
nail-patella syndrome 2 | 16
non-small cell lung cancer 2 | 2,890
ovarian cancer 2 | 8,520
pediatric high grade glioma 2 | 1,064
ulcerative colitis 2 | 1,819
Anorexia nervosa 1 | 80
Blastic phase chronic myeloid leukemia 1 | 58
Blau syndrome 1 | 9
Breast cancer 1 | 3,578
COPD 1 | 118
Carcinoma of thyroid 1 | 17
Cardiomyopathy 1 | 116
Cardiomyopathy, Dilated 1 | 83
Cardiomyopathy, Dilated, 1AA 1 | 1
Chronic Myelocytic Leukemia Accelerated Phase 1 | 59
Chronic obstructive pulmonary disease 1 | 184
Chronic phase chronic myeloid leukemia 1 | 45
Colitis, Ulcerative 1 | 59
Crohn's disease 1 | 321
Dilated cardiomyopathy 1 | 56
Duchenne muscular dystrophy 1 | 601
Endocardial Fibroelastosis 1 | 9
Endomyocardial Fibrosis 1 | 13
Familial isolated dilated cardiomyopathy 1 | 41
Highly variable clinical phenotype 1 | 150
Highly variable phenotype and severity 1 | 150
Highly variable phenotype, even within families 1 | 150
Hypertrophic Cardiomyopathy 1 | 117
Infantile onset spinocerebellar ataxia 1 | 7
LEFT VENTRICULAR NONCOMPACTION 10 1 | 40
LEFT VENTRICULAR NONCOMPACTION 8 1 | 40
Leprosy 1 | 73
Leukocyte adhesion deficiency 1 | 16
Liver Cirrhosis, Experimental 1 | 769
Myopathy 1 | 185
Neoplasm Invasiveness 1 | 161
Osteoporosis 1 | 363
Phenotypic variability 1 | 150
Philadelphia Chromosome Positive Chronic Myelocytic Leukemia 1 | 45
Philadelphia chromosome-positive acute lymphoblastic leukemia 1 | 47
X-linked lymphoproliferative syndrome 2 1 | 4
acute quadriplegic myopathy 1 | 1,158
adrenocortical carcinoma 1 | 1,428
adult high grade glioma 1 | 3,801
autosomal dominant Emery-Dreifuss muscular dystrophy 1 | 510
breast carcinoma 1 | 1,638
diabetes mellitus 1 | 1,728
dilated cardiomyopathy 1AA 1 | 1
ductal carcinoma in situ 1 | 1,745
facioscapulohumeral dystrophy 1 | 288
gastric cancer 1 | 459
group 3 medulloblastoma 1 | 4,104
group 4 medulloblastoma 1 | 1,855
hepatocellular carcinoma 1 | 547
lung cancer 1 | 4,740
non-small cell lung carcinoma 1 | 317
oligodendroglioma 1 | 2,850
pancreatic cancer 1 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 1 | 1,962
pituitary cancer 1 | 1,972
posterior fossa group A ependymoma 1 | 468
primitive neuroectodermal tumor 1 | 3,035
severe Alzheimer's disease 1 | 47
tuberculosis 1 | 2,010

Tissue

Blood and immune system 7 | 16,909
Cardiovascular System 7 | 15,192
Digestive Tract 7 | 17,369
Endocrine System 7 | 18,159
Female tissues 7 | 17,400
Liver and Pancreas 7 | 16,750
Male tissues 7 | 17,142
Nervous System 7 | 16,725
Respiratory system 7 | 16,393
Skin and soft tissues 7 | 17,230
Urinary Tract 7 | 16,678

Target Family

Non-IDG 6 | 12,091
Kinase 1 | 634

GO Function

LIM domain binding 7 | 7
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
LIM domain-binding protein 1 LDB1 Tbio Non-IDG -2.22623 164.4 206
Rab effector Noc2 RPH3AL Tbio Non-IDG -1.26757 23.0 148
LIM domain-binding protein 2 LDB2 Tbio Non-IDG -1.58628 38.6 191
Cysteine-rich protein 2-binding protein KAT14 Tbio Non-IDG -0.90082 7.81 111
Talin-1 TLN1 Tbio Non-IDG -1.94109 90.0 426
Receptor-interacting serine/threonine-protein kinase 2 RIPK2 Tchem Kinase -2.03990 107.3 474
Alpha-actinin-2 ACTN2 Tbio Non-IDG -1.89804 72.9 245