Development Level

Tbio 6 | 11,445
Tdark 2 | 6,588
Tchem 1 | 1,598

IMPC Phenotype

decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating magnesiu... 1 | 13
improved glucose tolerance 1 | 79
increased body length 1 | 32

Disease

Carcinoma 5 | 11,493
medulloblastoma, large-cell 5 | 6,241
ovarian cancer 5 | 8,520
atypical teratoid / rhabdoid tumor 4 | 5,112
glioblastoma 4 | 5,792
interstitial cystitis 4 | 2,312
invasive ductal carcinoma 4 | 2,951
lung adenocarcinoma 4 | 2,716
malignant mesothelioma 4 | 3,232
osteosarcoma 4 | 7,950
Multiple myeloma 3 | 1,332
Schizophrenia 3 | 1,160
adult high grade glioma 3 | 3,801
ductal carcinoma in situ 3 | 1,745
group 3 medulloblastoma 3 | 4,104
Astrocytoma, Pilocytic 2 | 3,081
Rheumatoid arthritis 2 | 1,191
cystic fibrosis 2 | 1,696
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
lung cancer 2 | 4,740
lung carcinoma 2 | 2,843
non-small cell lung cancer 2 | 2,890
pancreatic cancer 2 | 2,398
primary pancreatic ductal adenocarcinoma 2 | 1,109
primitive neuroectodermal tumor 2 | 3,035
psoriasis 2 | 6,694
ulcerative colitis 2 | 1,819
Acquired metabolic disease 1 | 336
Alcohol dependence 1 | 107
Alcoholic Intoxication, Chronic 1 | 289
Amyotrophic lateral sclerosis 1 | 451
Babinski Reflex 1 | 100
Bipolar Disorder 1 | 666
Branchiootic syndrome 1 | 12
Breast cancer 1 | 3,578
Cancer 1 | 2,499
Carbuncle 1 | 3
Cerebral atrophy 1 | 178
Chronic Lymphocytic Leukemia 1 | 262
Cognitive delay 1 | 608
Crohn's disease 1 | 321
Cystinuria 1 | 18
Degenerative brain disorder 1 | 100
Down syndrome 1 | 499
Duchenne muscular dystrophy 1 | 601
Dull intelligence 1 | 645
Epilepsy 1 | 792
Gastrointestinal system disease 1 | 54
Global developmental delay 1 | 608
Hartnup disease 1 | 13
Hyperactive behavior 1 | 91
Hyperekplexia 1 | 16
Hyperreflexia 1 | 209
Hypoplasia of corpus callosum 1 | 90
Intellectual disability 1 | 1,016
Irritation - emotion 1 | 68
Low intelligence 1 | 645
Mental Retardation 1 | 645
Mental and motor retardation 1 | 608
Mental deficiency 1 | 645
Microcephaly 1 | 166
Multiple system atrophy 1 | 29
Muscle hypotonia 1 | 571
Pick disease 1 | 1,894
Polycystic ovary syndrome 1 | 360
Poor school performance 1 | 645
Prostatic Neoplasms 1 | 495
Retinitis pigmentosa 28 1 | 19
SPASTIC TETRAPLEGIA, THIN CORPUS CALLOSUM, AND PROGRESSIVE MICROCEPHALY 1 | 1
Serine deficiency 1 | 9
Small head 1 | 374
Spastic Quadriplegia 1 | 42
Spondylosis 1 | 16
Stiff-Person syndrome 1 | 12
Supratentorial atrophy 1 | 94
Thrombocytosis 1 | 38
Treatment-resistant schizophrenia 1 | 6
X-linked cerebral adrenoleukodystrophy 1 | 116
active Crohn's disease 1 | 922
acute quadriplegic myopathy 1 | 1,158
adrenocortical carcinoma 1 | 1,428
aldosterone-producing adenoma 1 | 665
astrocytic glioma 1 | 2,597
astrocytoma 1 | 1,146
autosomal dominant Emery-Dreifuss muscular dystrophy 1 | 510
colon cancer 1 | 1,478
diabetes mellitus 1 | 1,728
ependymoma 1 | 4,679
intraductal papillary-mucinous adenoma (IPMA) 1 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 1 | 3,291
medulloblastoma 1 | 720
pediatric high grade glioma 1 | 1,064
primary Sjogren syndrome 1 | 735
progressive supranuclear palsy 1 | 676
sonic hedgehog group medulloblastoma 1 | 467
subependymal giant cell astrocytoma 1 | 2,287
substance-related disorder 1 | 162
tuberculosis 1 | 2,010
tuberculosis and treatment for 3 months 1 | 179

Tissue

Digestive Tract 9 | 17,369
Endocrine System 9 | 18,159
Female tissues 9 | 17,400
Nervous System 9 | 16,725
Blood and immune system 8 | 16,909
Skin and soft tissues 8 | 17,230
Urinary Tract 8 | 16,678
Cardiovascular System 7 | 15,192
Liver and Pancreas 7 | 16,750
Male tissues 7 | 17,142
Respiratory system 7 | 16,393

Target Family

Non-IDG 5 | 12,091
Transporter 4 | 473

GO Function

L-serine transmembrane transpo... 9 | 9
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Serine incorporator 5 SERINC5 Tbio Non-IDG -1.50535 34.0 11
Serine incorporator 4 SERINC4 Tdark Non-IDG 0.00000 33
Serine incorporator 3 SERINC3 Tbio Non-IDG -2.44903 264.3 131
Neutral amino acid transporter A SLC1A4 Tbio Transporter -1.77799 59.3 148
Putative sodium-coupled neutral amino acid transporter 7 SLC38A7 Tdark Transporter -0.52246 3.33 16
Serine incorporator 2 SERINC2 Tbio Non-IDG -0.89181 7.54 119
Serine incorporator 1 SERINC1 Tbio Non-IDG -1.50356 29.4 97
Asc-type amino acid transporter 1 SLC7A10 Tbio Transporter -1.00874 10.1 74
Neutral amino acid transporter B(0) SLC1A5 Tchem Transporter -2.60102 388.3 161