Development Level

Tbio 4 | 11,445
Tchem 2 | 1,598

IMPC Phenotype

abnormal gait 1 | 69
abnormal hindlimb morphology 1 | 2
abnormal locomotor activation 1 | 16
abnormal spine curvature 1 | 9
corneal opacity 1 | 32
decreased circulating free fat... 1 | 31
decreased circulating glycerol... 1 | 16
decreased total body fat amoun... 1 | 207
hyperactivity 1 | 148
increased bone mineral content 1 | 108
increased circulating alkaline... 1 | 122
increased hemoglobin content 1 | 45

Disease

Carcinoma 5 | 11,493
ovarian cancer 4 | 8,520
psoriasis 4 | 6,694
osteosarcoma 3 | 7,950
Dysphasia 2 | 23
Frontotemporal dementia 2 | 51
Inclusion body myopathy with Paget disease of bone and frontotemporal dementia 2 | 13
Multiple myeloma 2 | 1,332
Schizophrenia 2 | 1,160
malignant mesothelioma 2 | 3,232
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
22q11 Deletion Syndrome 1 | 10
22q11 partial monosomy syndrome 1 | 9
22q11.2 deletion syndrome 1 | 8
Abnormal brain FDG positron emission tomography 1 | 9
Abnormal nerve conduction velocity 1 | 4
Abnormality of aortic arch 1 | 9
Abnormality of the pharynx 1 | 19
Abnormality of the tonsils 1 | 10
Acne 1 | 52
Alexia 1 | 6
Alkaline phosphatase serum increased 1 | 29
Aphasia 1 | 26
Apraxias 1 | 27
Back Pain 1 | 7
Behavioral variant of frontotemporal dementia 1 | 8
CONOTRUNCAL ANOMALY FACE SYNDROME 1 | 9
Compulsive hoarding 1 | 7
Congenital hypoplasia of kidney 1 | 32
Convex nasal bridge 1 | 57
Corneal Neovascularization 1 | 13
Developmental arithmetic disorder 1 | 8
DiGeorge syndrome 1 | 47
Difficulty making arithmetical calculations 1 | 8
Dysgraphia 1 | 20
Dyslexia 1 | 43
Dysseborrheic dermatitis 1 | 13
EEG with continuous slow activity 1 | 7
Echolalia 1 | 12
Excess nuchal skin 1 | 30
Fasciculation, Tongue 1 | 8
Fatigable weakness of respiratory muscles 1 | 28
Fatigable weakness of swallowing muscles 1 | 28
Forgetful 1 | 40
Frontotemporal cerebral atrophy 1 | 8
Gait imbalance 1 | 17
Grammar-specific speech disorder 1 | 6
Hammer Toe 1 | 23
Hypernasal voice 1 | 39
Hyperorality 1 | 7
Hypocalcemia 1 | 32
Hypoparathyroidism 1 | 41
Hypoplastic lobules 1 | 11
Impaired T cell function 1 | 14
Irritation - emotion 1 | 68
Lower limb hyperreflexia 1 | 10
Memory Loss 1 | 40
Memory impairment 1 | 40
Mild Mental Retardation 1 | 70
Muscle Cramp 1 | 55
Muscle weakness of limb 1 | 21
Myalgia 1 | 54
Nasal voice 1 | 39
Occipital myelomeningocele 1 | 8
Overfolded helix 1 | 24
Paget's disease of bone 1 | 36
Pain 1 | 103
Paralysed 1 | 42
Pelvic girdle amyotrophy 1 | 2
Pelvic girdle weakness 1 | 7
Persistant truncus arteriosus 1 | 17
Platybasia 1 | 13
Poor speech 1 | 37
Primary Progressive Nonfluent Aphasia 1 | 7
Problems speaking 1 | 37
Progressive non-fluent aphasia 1 | 7
Prominent nasal bridge 1 | 57
Reflex, Ankle, Absent 1 | 8
Repeated speech 1 | 9
Restlessness 1 | 14
Restrictive behavior 1 | 7
Restrictive behavior, interests, and activities 1 | 7
Rimmed vacuoles on biopsy 1 | 15
Rotting teeth 1 | 73
Scapular weakness 1 | 23
Seborrheic dermatitis 1 | 31
Semantic Dementia 1 | 7
Shoulder girdle muscle atrophy 1 | 6
Shoulder girdle weakness 1 | 10
Shoulder weakness 1 | 10
Shprintzen syndrome 1 | 9
Small thymus 1 | 13
Social disinhibition 1 | 14
Spoken Word Recognition Deficit 1 | 6
Stevens-Johnson syndrome 1 | 92
Temporal cortical atrophy 1 | 6
Tetany 1 | 18
Velocardiofacial syndrome 1 | 46
Winged scapula 1 | 23
Xerostomia 1 | 42

Tissue

Blood and immune system 6 | 16,909
Cardiovascular System 6 | 15,192
Digestive Tract 6 | 17,369
Endocrine System 6 | 18,159
Female tissues 6 | 17,400
Liver and Pancreas 6 | 16,750
Male tissues 6 | 17,142
Nervous System 6 | 16,725
Respiratory system 6 | 16,393
Skin and soft tissues 6 | 17,230
Urinary Tract 6 | 16,678

Target Family

Non-IDG 4 | 12,091
Enzyme 1 | 4,145
Kinase 1 | 634

GO Function

K48-linked polyubiquitin modif... 6 | 6
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Ubiquitin carboxyl-terminal hydrolase MINDY-2 MINDY2 Tbio Non-IDG -0.30103 1.50 54
Ubiquitin carboxyl-terminal hydrolase MINDY-1 MINDY1 Tbio Non-IDG 0.00000 0.42 62
Ubiquitin recognition factor in ER-associated degradation protein 1 UFD1 Tbio Non-IDG -1.78158 54.5 187
UBX domain-containing protein 1 UBXN1 Tbio Non-IDG -0.77492 6.54 100
Inhibitor of nuclear factor kappa-B kinase subunit epsilon IKBKE Tchem Kinase -1.65479 43.0 434
Transitional endoplasmic reticulum ATPase VCP Tchem Enzyme -2.84978 736.4 416