Development Level

Tbio 6 | 11,445
Tchem 2 | 1,598

IMPC Phenotype

preweaning lethality, complete... 1 | 979

Disease

Carcinoma 7 | 11,493
glioblastoma 6 | 5,792
ovarian cancer 5 | 8,520
psoriasis 5 | 6,694
atypical teratoid / rhabdoid tumor 4 | 5,112
diabetes mellitus 4 | 1,728
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
medulloblastoma, large-cell 4 | 6,241
oligodendroglioma 4 | 2,850
osteosarcoma 4 | 7,950
Cancer 3 | 2,499
Kidney cancer 3 | 2,613
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
primitive neuroectodermal tumor 3 | 3,035
tuberculosis 3 | 2,010
Amyotrophic lateral sclerosis 2 | 451
Breast cancer 2 | 3,578
Carcinoma, Hepatocellular 2 | 228
Carcinoma, Non-Small-Cell Lung 2 | 107
Down syndrome 2 | 499
Liver carcinoma 2 | 240
Pick disease 2 | 1,894
adult high grade glioma 2 | 3,801
dermatomyositis 2 | 966
ependymoma 2 | 4,679
group 3 medulloblastoma 2 | 4,104
group 4 medulloblastoma 2 | 1,855
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
lung cancer 2 | 4,740
lung carcinoma 2 | 2,843
mucosa-associated lymphoid tissue lymphoma 2 | 484
non-small cell lung carcinoma 2 | 317
sonic hedgehog group medulloblastoma 2 | 467
subependymal giant cell astrocytoma 2 | 2,287
ulcerative colitis 2 | 1,819
Acquired metabolic disease 1 | 336
Acquired scoliosis 1 | 281
Acute kidney injury 1 | 70
Adenocarcinoma 1 | 122
Adenoma 1 | 167
Amphetamine-Related Disorders 1 | 74
Autistic Disorder 1 | 364
Bladder Neoplasm 1 | 112
Breast Neoplasms 1 | 445
Carcinoma, Renal Cell 1 | 124
Carcinoma, Squamous Cell 1 | 110
Cervical cancer 1 | 24
Chemical and Drug Induced Liver Injury 1 | 195
Chronic obstructive pulmonary disease 1 | 184
Cocaine Dependence 1 | 51
Curvature of spine 1 | 282
Decreased platelet count 1 | 111
Dengue disease 1 | 23
Diabetes Mellitus, Non-Insulin-Dependent 1 | 145
Diabetes Mellitus, Noninsulin-Dependent 1 | 31
Diabetes Mellitus, Type 2 1 | 142
Disease Progression 1 | 136
Drug allergy 1 | 36
Essential tremor 1 | 28
Fanconi anemia 1 | 56
Gaucher disease type 1 1 | 180
Glioma 1 | 74
Hypertension 1 | 396
Infertility 1 | 188
Inflammation 1 | 120
Irregular hyperpigmentation 1 | 33
Kidney Calculi 1 | 7
Kidney Diseases 1 | 114
Leukopenia 1 | 72
Liver Neoplasms, Experimental 1 | 59
Liver disease 1 | 237
Lung Neoplasms 1 | 232
Mammary Neoplasms 1 | 425
Mammary Neoplasms, Experimental 1 | 154
Mouth Neoplasms 1 | 55
Necrosis 1 | 53
Neoplasm Invasiveness 1 | 161
Non-alcoholic Fatty Liver Disease 1 | 42
Nonorganic psychosis 1 | 84
Parkinson Disease 1 | 64
Peripheral Neuropathy 1 | 134
Polycystic ovary syndrome 1 | 360
Precancerous Conditions 1 | 80
Psychotic Disorders 1 | 151
Renal Cell Carcinoma 1 | 214
Sarcoma 1 | 62
Short palpebral fissure 1 | 38
Squamous cell carcinoma 1 | 129
Stomach Neoplasms 1 | 300
Thrombocytopenia 1 | 197
Urinary Bladder Neoplasms 1 | 114
Xeroderma pigmentosum group D 1 | 33
active Crohn's disease 1 | 922
active ulcerative colitis 1 | 764
hereditary spastic paraplegia 1 | 318
hypopigmented skin patch 1 | 59
pediatric high grade glioma 1 | 1,064
posterior fossa group A ependymoma 1 | 468
progressive supranuclear palsy 1 | 676

Tissue

Blood and immune system 8 | 16,909
Cardiovascular System 8 | 15,192
Digestive Tract 8 | 17,369
Endocrine System 8 | 18,159
Female tissues 8 | 17,400
Liver and Pancreas 8 | 16,750
Male tissues 8 | 17,142
Nervous System 8 | 16,725
Respiratory system 8 | 16,393
Skin and soft tissues 8 | 17,230
Urinary Tract 8 | 16,678

Target Family

Enzyme 5 | 4,145
Non-IDG 2 | 12,091
Kinase 1 | 634

GO Function

JUN kinase binding 8 | 8
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Focal adhesion kinase 1 PTK2 Tchem Kinase -3.06733 1038.3 2013
Kinesin-1 heavy chain KIF5B Tbio Non-IDG -2.32485 196.1 326
C-Jun-amino-terminal kinase-interacting protein 4 SPAG9 Tbio Enzyme -2.45490 258.6 149
Mitotic spindle assembly checkpoint protein MAD2B MAD2L2 Tbio Non-IDG -1.69227 56.5 111
Dual specificity protein phosphatase 10 DUSP10 Tbio Enzyme -1.51719 38.2 270
C-Jun-amino-terminal kinase-interacting protein 1 MAPK8IP1 Tbio Enzyme -2.85543 697.4 180
C-Jun-amino-terminal kinase-interacting protein 3 MAPK8IP3 Tbio Enzyme -1.68844 56.5 128
Glutathione S-transferase P GSTP1 Tchem Enzyme -3.20051 1734.8 519