Development Level

Tbio 20 | 11,445
Tchem 7 | 1,598
Tclin 5 | 613

IMPC Phenotype

preweaning lethality, complete... 3 | 979
abnormal behavior 2 | 298
decreased body length 2 | 101
abnormal bone structure 1 | 187
abnormal coat-hair pigmentatio... 1 | 64
abnormal embryo size 1 | 220
abnormal retina morphology 1 | 71
abnormal rib morphology 1 | 10
abnormal sleep behavior 1 | 70
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating glucose ... 1 | 126
decreased circulating iron lev... 1 | 32
decreased circulating triglyce... 1 | 79
decreased grip strength 1 | 116
decreased heart rate 1 | 18
increased circulating iron lev... 1 | 30
increased lean body mass 1 | 172
increased total body fat amoun... 1 | 134
male infertility 1 | 123
polycystic kidney 1 | 15
preweaning lethality, incomple... 1 | 499
vertebral fusion 1 | 23

Disease

Carcinoma 26 | 11,493
osteosarcoma 19 | 7,950
ovarian cancer 18 | 8,520
medulloblastoma, large-cell 14 | 6,241
lung cancer 13 | 4,740
Cancer 11 | 2,499
psoriasis 11 | 6,694
diabetes mellitus 9 | 1,728
intraductal papillary-mucinous neoplasm (IPMN) 9 | 3,291
atypical teratoid / rhabdoid tumor 8 | 5,112
group 3 medulloblastoma 8 | 4,104
Bipolar Disorder 7 | 666
Breast cancer 7 | 3,578
malignant mesothelioma 7 | 3,232
oligodendroglioma 7 | 2,850
Depressive disorder 6 | 409
Mental Depression 6 | 333
Multiple myeloma 6 | 1,332
adult high grade glioma 6 | 3,801
ependymoma 6 | 4,679
glioblastoma 6 | 5,792
Intellectual disability 5 | 1,016
Pick disease 5 | 1,894
astrocytic glioma 5 | 2,597
astrocytoma 5 | 1,146
interstitial cystitis 5 | 2,312
lung carcinoma 5 | 2,843
primitive neuroectodermal tumor 5 | 3,035
subependymal giant cell astrocytoma 5 | 2,287
Astrocytoma, Pilocytic 4 | 3,081
Crohn's disease 4 | 321
Hypertension 4 | 396
Kidney cancer 4 | 2,613
Neurodegenerative disease 4 | 414
Obesity 4 | 678
Prostatic Neoplasms 4 | 495
Rheumatoid arthritis 4 | 1,191
Schizophrenia 4 | 1,160
Waldenstrons macroglobulinemia 4 | 765
cystic fibrosis 4 | 1,696
dermatomyositis 4 | 966
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
invasive ductal carcinoma 4 | 2,951
pancreatic cancer 4 | 2,398
ulcerative colitis 4 | 1,819
Atopic dermatitis 3 | 952
Autosomal recessive predisposition 3 | 1,442
Breast Neoplasms 3 | 445
Congenital Heart Defects 3 | 58
Hypertensive disease 3 | 292
Major Depressive Disorder 3 | 301
Mammary Neoplasms 3 | 425
Melanoma 3 | 711
Mood Disorders 3 | 184
Multiple Sclerosis 3 | 540
Myocardial Ischemia 3 | 169
Pancreatic Neoplasm 3 | 85
Pancreatic Neoplasms 3 | 85
Primary cutaneous T-cell lymphoma 3 | 29
Unipolar Depression 3 | 250
active ulcerative colitis 3 | 764
acute quadriplegic myopathy 3 | 1,158
aldosterone-producing adenoma 3 | 665
breast carcinoma 3 | 1,638
colon cancer 3 | 1,478
cutaneous lupus erythematosus 3 | 1,057
group 4 medulloblastoma 3 | 1,855
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
juvenile dermatomyositis 3 | 1,187
lung adenocarcinoma 3 | 2,716
non-small cell lung cancer 3 | 2,890
pituitary cancer 3 | 1,972
progressive supranuclear palsy 3 | 676
sarcoidosis 3 | 370
Alzheimer's disease 2 | 658
Amyotrophic lateral sclerosis 2 | 451
Atherosclerosis 2 | 291
Cerebrovascular disease 2 | 238
Chronic obstructive pulmonary disease 2 | 184
Contact Dermatitis 2 | 81
Heart disease 2 | 306
Hepatomegaly 2 | 285
Kidney disease 2 | 430
Male infertility 2 | 206
Neoplasm Invasiveness 2 | 161
Parkinson's disease 2 | 392
Peripheral T-cell lymphoma 2 | 25
Vascular disease 2 | 319
adrenocortical carcinoma 2 | 1,428
chronic rhinosinusitis 2 | 512
esophageal adenocarcinoma 2 | 737
gastric carcinoma 2 | 807
nasopharyngeal carcinoma 2 | 1,058
pancreatic carcinoma 2 | 562
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
pediatric high grade glioma 2 | 1,064
primary pancreatic ductal adenocarcinoma 2 | 1,109
sonic hedgehog group medulloblastoma 2 | 467
spina bifida 2 | 1,074
urothelial carcinoma 2 | 318

Tissue

Endocrine System 32 | 18,159
Digestive Tract 31 | 17,369
Female tissues 31 | 17,400
Respiratory system 31 | 16,393
Blood and immune system 30 | 16,909
Cardiovascular System 30 | 15,192
Liver and Pancreas 30 | 16,750
Male tissues 30 | 17,142
Nervous System 30 | 16,725
Skin and soft tissues 30 | 17,230
Urinary Tract 30 | 16,678

Target Family

Non-IDG 13 | 12,091
Enzyme 7 | 4,145
Transcription Factor 5 | 1,400
Kinase 4 | 634
Epigenetic 2 | 242
Nuclear Receptor 1 | 48

GO Function

Hsp90 protein binding 32 | 32
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Nucleotide-binding oligomerization domain-containing protein 2 NOD2 Tclin Non-IDG -3.13621 1445.5 370
Protein unc-45 homolog B UNC45B Tbio Non-IDG -1.54873 42.8 123
Telomere length regulation protein TEL2 homolog TELO2 Tbio Non-IDG -0.93554 9.48 94
40S ribosomal protein S3 RPS3 Tbio Non-IDG -2.19489 157.7 218
Eukaryotic translation initiation factor 2-alpha kinase 3 EIF2AK3 Tchem Kinase -3.05781 896.8 450
Histone deacetylase 8 HDAC8 Tclin Epigenetic -2.41838 263.5 487
Serine/threonine-protein phosphatase with EF-hands 2 PPEF2 Tbio Enzyme -0.26680 1.77 58
Aryl hydrocarbon receptor AHR Tchem Transcription Factor 0.00000 773
Vascular endothelial growth factor receptor 2 KDR Tclin Kinase -3.67555 4544.8 2373
Hsp90 co-chaperone Cdc37 CDC37 Tbio Non-IDG -0.96438 12.8 409