Development Level

Tbio 26 | 11,445
Tchem 8 | 1,598
Tclin 3 | 613

Collection

GPCR: IDG Consortium (Complete... 1 | 25

IMPC Phenotype

preweaning lethality, complete... 2 | 979
preweaning lethality, incomple... 2 | 499
abnormal sleep behavior 1 | 70
abnormal spinal cord morpholog... 1 | 9
decreased body length 1 | 101
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating triglyce... 1 | 79
increased grip strength 1 | 41
increased mean corpuscular hem... 1 | 36
increased prepulse inhibition 1 | 32
prenatal lethality prior to he... 1 | 87

Disease

ovarian cancer 23 | 8,520
Carcinoma 19 | 11,493
medulloblastoma, large-cell 18 | 6,241
osteosarcoma 18 | 7,950
psoriasis 16 | 6,694
atypical teratoid / rhabdoid tumor 14 | 5,112
glioblastoma 13 | 5,792
group 3 medulloblastoma 13 | 4,104
malignant mesothelioma 12 | 3,232
invasive ductal carcinoma 11 | 2,951
lung cancer 11 | 4,740
Cancer 10 | 2,499
ependymoma 10 | 4,679
intraductal papillary-mucinous adenoma (IPMA) 10 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 8 | 3,291
primitive neuroectodermal tumor 8 | 3,035
Pick disease 7 | 1,894
intraductal papillary-mucinous carcinoma (IPMC) 7 | 2,989
lung adenocarcinoma 7 | 2,716
non-small cell lung cancer 7 | 2,890
Breast cancer 6 | 3,578
Multiple myeloma 6 | 1,332
Neurodegenerative disease 6 | 414
Parkinson's disease 6 | 392
astrocytoma 6 | 1,146
breast carcinoma 6 | 1,638
tuberculosis 6 | 2,010
Alzheimer's disease 5 | 658
Astrocytoma, Pilocytic 5 | 3,081
Autosomal recessive predisposition 5 | 1,442
Bipolar Disorder 5 | 666
Rheumatoid arthritis 5 | 1,191
adult high grade glioma 5 | 3,801
astrocytic glioma 5 | 2,597
group 4 medulloblastoma 5 | 1,855
interstitial cystitis 5 | 2,312
oligodendroglioma 5 | 2,850
pancreatic cancer 5 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
ulcerative colitis 5 | 1,819
Intellectual disability 4 | 1,016
Kidney cancer 4 | 2,613
Waldenstrons macroglobulinemia 4 | 765
active Crohn's disease 4 | 922
adrenocortical carcinoma 4 | 1,428
colon cancer 4 | 1,478
cutaneous lupus erythematosus 4 | 1,057
diabetes mellitus 4 | 1,728
ductal carcinoma in situ 4 | 1,745
esophageal adenocarcinoma 4 | 737
juvenile dermatomyositis 4 | 1,187
lung carcinoma 4 | 2,843
Atopic dermatitis 3 | 952
Autistic Disorder 3 | 364
Dementia 3 | 175
Depressive disorder 3 | 409
Down syndrome 3 | 499
Dysarthria 3 | 192
Dystonia 3 | 164
Dystonic disease 3 | 106
Huntington's disease 3 | 76
Leprosy 3 | 73
Melanoma 3 | 711
Nerve Degeneration 3 | 121
Optic Atrophy 3 | 242
Ovarian Neoplasms 3 | 102
Prostatic Neoplasms 3 | 495
Toxic encephalopathy 3 | 141
chronic rhinosinusitis 3 | 512
cystic fibrosis 3 | 1,696
nasopharyngeal carcinoma 3 | 1,058
pediatric high grade glioma 3 | 1,064
pituitary cancer 3 | 1,972
progressive supranuclear palsy 3 | 676
sarcoidosis 3 | 370
spina bifida 3 | 1,074
subependymal giant cell astrocytoma 3 | 2,287
Amyotrophic lateral sclerosis 2 | 451
Attention deficit hyperactivity disorder 2 | 278
Bradykinesia 2 | 34
Cocaine-Related Disorders 2 | 92
Colonic Neoplasms 2 | 142
Diarrhea 2 | 253
Endometriosis 2 | 540
Epilepsy 2 | 792
Hyperreflexia 2 | 209
Kennedy's disease 2 | 11
Leukemia 2 | 104
Lung Neoplasms 2 | 232
Machado-Joseph disease 2 | 18
Manganese Poisoning 2 | 11
Muscle Spasticity 2 | 195
Stomach Neoplasms 2 | 300
Vascular disease 2 | 319
acute quadriplegic myopathy 2 | 1,158
dermatomyositis 2 | 966
glioblastoma multiforme 2 | 142
primary pancreatic ductal adenocarcinoma 2 | 1,109
sonic hedgehog group medulloblastoma 2 | 467
urothelial carcinoma 2 | 318

Tissue

Endocrine System 37 | 18,159
Blood and immune system 36 | 16,909
Cardiovascular System 36 | 15,192
Digestive Tract 36 | 17,369
Female tissues 36 | 17,400
Liver and Pancreas 36 | 16,750
Male tissues 36 | 17,142
Nervous System 36 | 16,725
Respiratory system 36 | 16,393
Skin and soft tissues 36 | 17,230
Urinary Tract 36 | 16,678

Target Family

Non-IDG 23 | 12,091
Enzyme 8 | 4,145
Kinase 2 | 634
Transcription Factor 2 | 1,400
Epigenetic 1 | 242
GPCR 1 | 408

GO Function

Hsp70 protein binding 37 | 37
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Diphosphomevalonate decarboxylase MVD Tchem Enzyme -2.09917 118.7 136
Nucleotide-binding oligomerization domain-containing protein 2 NOD2 Tclin Non-IDG -3.13621 1445.5 370
Histone deacetylase 8 HDAC8 Tclin Epigenetic -2.41838 263.5 487
Sacsin SACS Tbio Non-IDG -2.64601 427.1 19
DnaJ homolog subfamily B member 12 DNAJB12 Tbio Non-IDG -0.87804 6.09 135
Serine/threonine-protein phosphatase with EF-hands 2 PPEF2 Tbio Enzyme -0.26680 1.77 58
Hsc70-interacting protein ST13 Tbio Non-IDG -1.74684 82.3 247
RING finger protein 207 RNF207 Tbio Non-IDG -0.31727 2.60 96
40S ribosomal protein S3 RPS3 Tbio Non-IDG -2.19489 157.7 218
IQ domain-containing protein G IQCG Tbio Non-IDG -0.38322 3.91 43