Development Level

Tbio 25 | 11,178
Tchem 9 | 1,885
Tclin 3 | 612

Collection

GPCR: IDG Consortium (Complete... 1 | 25

IMPC Phenotype

preweaning lethality, complete... 2 | 979
preweaning lethality, incomple... 2 | 499
abnormal sleep behavior 1 | 70
abnormal spinal cord morpholog... 1 | 9
decreased body length 1 | 101
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating triglyce... 1 | 79
increased grip strength 1 | 41
increased mean corpuscular hem... 1 | 36
increased prepulse inhibition 1 | 32
prenatal lethality prior to he... 1 | 87

Disease

ovarian cancer 23 | 8,297
Carcinoma 19 | 11,192
medulloblastoma, large-cell 18 | 6,086
osteosarcoma 18 | 7,766
psoriasis 16 | 6,514
atypical teratoid / rhabdoid tumor 14 | 4,971
glioblastoma 13 | 5,635
group 3 medulloblastoma 13 | 4,002
malignant mesothelioma 12 | 3,135
invasive ductal carcinoma 11 | 2,867
lung cancer 11 | 4,607
Cancer 10 | 2,388
ependymoma 10 | 4,559
intraductal papillary-mucinous adenoma (IPMA) 10 | 2,872
intraductal papillary-mucinous neoplasm (IPMN) 8 | 3,204
primitive neuroectodermal tumor 8 | 2,957
Pick disease 7 | 1,856
intraductal papillary-mucinous carcinoma (IPMC) 7 | 2,902
lung adenocarcinoma 7 | 2,627
non-small cell lung cancer 7 | 2,799
Breast cancer 6 | 3,469
Multiple myeloma 6 | 1,296
Neurodegenerative disease 6 | 402
Parkinson's disease 6 | 378
astrocytoma 6 | 1,113
breast carcinoma 6 | 1,589
tuberculosis 6 | 1,963
Alzheimer's disease 5 | 640
Astrocytoma, Pilocytic 5 | 3,006
Autosomal recessive predisposition 5 | 1,407
Bipolar Disorder 5 | 646
Rheumatoid arthritis 5 | 1,156
adult high grade glioma 5 | 3,701
astrocytic glioma 5 | 2,530
group 4 medulloblastoma 5 | 1,806
interstitial cystitis 5 | 2,237
oligodendroglioma 5 | 2,768
pancreatic cancer 5 | 2,322
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,911
ulcerative colitis 5 | 1,765
Intellectual disability 4 | 998
Kidney cancer 4 | 2,548
Waldenstrons macroglobulinemia 4 | 742
active Crohn's disease 4 | 882
adrenocortical carcinoma 4 | 1,385
colon cancer 4 | 1,428
cutaneous lupus erythematosus 4 | 1,016
diabetes mellitus 4 | 1,683
ductal carcinoma in situ 4 | 1,686
esophageal adenocarcinoma 4 | 696
juvenile dermatomyositis 4 | 1,147
lung carcinoma 4 | 2,755
Atopic dermatitis 3 | 915
Autistic Disorder 3 | 358
Dementia 3 | 172
Depressive disorder 3 | 401
Down syndrome 3 | 480
Dysarthria 3 | 190
Dystonia 3 | 163
Dystonic disease 3 | 105
Huntington's disease 3 | 75
Leprosy 3 | 72
Melanoma 3 | 689
Nerve Degeneration 3 | 118
Optic Atrophy 3 | 239
Ovarian Neoplasms 3 | 96
Prostatic Neoplasms 3 | 472
Toxic encephalopathy 3 | 139
chronic rhinosinusitis 3 | 505
cystic fibrosis 3 | 1,629
nasopharyngeal carcinoma 3 | 1,024
pediatric high grade glioma 3 | 1,035
pituitary cancer 3 | 1,915
progressive supranuclear palsy 3 | 656
sarcoidosis 3 | 357
spina bifida 3 | 1,053
subependymal giant cell astrocytoma 3 | 2,230
Amyotrophic lateral sclerosis 2 | 437
Attention deficit hyperactivity disorder 2 | 272
Bradykinesia 2 | 34
Colonic Neoplasms 2 | 133
Diarrhea 2 | 245
Endometriosis 2 | 521
Epilepsy 2 | 775
Hyperreflexia 2 | 208
Kennedy's disease 2 | 11
Leukemia 2 | 103
Liver Cirrhosis, Experimental 2 | 733
Machado-Joseph disease 2 | 16
Manganese Poisoning 2 | 11
Muscle Spasticity 2 | 192
Progressive disorder 2 | 139
Stomach Neoplasms 2 | 287
Vascular disease 2 | 294
acute quadriplegic myopathy 2 | 1,133
dermatomyositis 2 | 941
glioblastoma multiforme 2 | 139
primary pancreatic ductal adenocarcinoma 2 | 1,071
sonic hedgehog group medulloblastoma 2 | 459
urothelial carcinoma 2 | 303

Tissue

Endocrine System 37 | 18,159
Blood and immune system 36 | 16,909
Cardiovascular System 36 | 15,192
Digestive Tract 36 | 17,369
Female tissues 36 | 17,400
Liver and Pancreas 36 | 16,750
Male tissues 36 | 17,142
Nervous System 36 | 16,725
Respiratory system 36 | 16,393
Skin and soft tissues 36 | 17,230
Urinary Tract 36 | 16,678

Target Family

Non-IDG 23 | 12,091
Enzyme 8 | 4,145
Kinase 2 | 634
Transcription Factor 2 | 1,400
Epigenetic 1 | 242
GPCR 1 | 408

GO Function

Hsp70 protein binding 37 | 37
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
DnaJ homolog subfamily A member 3, mitochondrial DNAJA3 Tbio Non-IDG -1.55298 43.3 192
Diphosphomevalonate decarboxylase MVD Tchem Enzyme -2.09917 118.7 136
Nucleotide-binding oligomerization domain-containing protein 2 NOD2 Tclin Non-IDG -3.13621 1445.5 370
DnaJ homolog subfamily B member 12 DNAJB12 Tbio Non-IDG -0.87804 6.09 135
IQ domain-containing protein G IQCG Tbio Non-IDG -0.38322 3.91 43
Sacsin SACS Tbio Non-IDG -2.64601 427.1 19
Histone deacetylase 8 HDAC8 Tclin Epigenetic -2.41838 263.5 487
Hsc70-interacting protein ST13 Tbio Non-IDG -1.74684 82.3 247
RING finger protein 207 RNF207 Tbio Non-IDG -0.31727 2.60 96
40S ribosomal protein S3 RPS3 Tbio Non-IDG -2.19489 157.7 218