Development Level

Tbio 11 | 11,445
Tchem 1 | 1,598
Tclin 1 | 613
Tdark 1 | 6,588

IMPC Phenotype

abnormal bone structure 1 | 187
abnormal embryo size 1 | 220
abnormal liver size 1 | 5
abnormal pericardium morpholog... 1 | 26
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 53
decreased circulating serum al... 1 | 82
decreased threshold for audito... 1 | 26
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
hypoactivity 1 | 132
preweaning lethality, complete... 1 | 979
short tibia 1 | 97

Disease

Carcinoma 11 | 11,493
glioblastoma 9 | 5,792
ovarian cancer 8 | 8,520
atypical teratoid / rhabdoid tumor 7 | 5,112
medulloblastoma, large-cell 7 | 6,241
osteosarcoma 7 | 7,950
adult high grade glioma 6 | 3,801
ependymoma 6 | 4,679
lung cancer 6 | 4,740
Breast cancer 5 | 3,578
group 3 medulloblastoma 5 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
invasive ductal carcinoma 5 | 2,951
Kidney cancer 4 | 2,613
astrocytic glioma 4 | 2,597
group 4 medulloblastoma 4 | 1,855
non-small cell lung cancer 4 | 2,890
oligodendroglioma 4 | 2,850
primary pancreatic ductal adenocarcinoma 4 | 1,109
Astrocytoma, Pilocytic 3 | 3,081
Cancer 3 | 2,499
Carcinoma, Hepatocellular 3 | 228
Liver carcinoma 3 | 240
Melanoma 3 | 711
ductal carcinoma in situ 3 | 1,745
interstitial cystitis 3 | 2,312
lung carcinoma 3 | 2,843
pancreatic cancer 3 | 2,398
Brain Neoplasms 2 | 33
Duchenne muscular dystrophy 2 | 601
Joubert syndrome 2 | 66
Liver Cirrhosis, Experimental 2 | 769
Pick disease 2 | 1,894
Schizophrenia 2 | 1,160
Skin cancer 2 | 469
acute myeloid leukemia 2 | 783
astrocytoma 2 | 1,146
breast carcinoma 2 | 1,638
colon cancer 2 | 1,478
cystic fibrosis 2 | 1,696
diabetes mellitus 2 | 1,728
fibroadenoma 2 | 559
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
juvenile dermatomyositis 2 | 1,187
lung adenocarcinoma 2 | 2,716
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
pituitary cancer 2 | 1,972
primitive neuroectodermal tumor 2 | 3,035
psoriasis 2 | 6,694
subependymal giant cell astrocytoma 2 | 2,287
ulcerative colitis 2 | 1,819
Acquired immunodeficiency syndrome 1 | 197
Adenocarcinoma of lung 1 | 142
Amyotrophic lateral sclerosis 1 | 451
Atopic dermatitis 1 | 952
Atrial Fibrillation 1 | 124
Chronic heart failure 1 | 46
Congenital anomaly of face 1 | 56
Congenital hypoplasia of kidney 1 | 32
Congenital ocular coloboma (disorder) 1 | 40
Disease Models, Animal 1 | 155
Distortion of face 1 | 46
Dysmorphic facies 1 | 46
Epidermodysplasia verruciformis 1 | 21
Extinguished electroretinogram 1 | 15
Feingold syndrome 1 | 14
Funny looking face 1 | 46
Heart disease 1 | 306
Keratoconus 1 | 113
Liver cancer 1 | 604
Liver neoplasms 1 | 130
Pityriasis versicolor 1 | 19
Precancerous Conditions 1 | 80
Presbyopia 1 | 20
Retinal Degeneration 1 | 106
Retinal Dysplasia 1 | 11
Salmonellosis 1 | 42
Typhoid fever 1 | 22
Waldenstrons macroglobulinemia 1 | 765
Weight Gain 1 | 100
active Crohn's disease 1 | 922
acute quadriplegic myopathy 1 | 1,158
adrenocortical carcinoma 1 | 1,428
atypical teratoid/rhabdoid tumor 1 | 357
esophageal adenocarcinoma 1 | 737
facial deformity 1 | 46
hepatocellular carcinoma 1 | 547
hereditary spastic paraplegia 1 | 318
hypoparathyroidism-retardation-dysmorphism syndrome 1 | 7
interstitial lung disease 1 | 298
intraductal papillary-mucinous adenoma (IPMA) 1 | 2,955
limb girdle muscular dystrophy 2I 1 | 32
mucosa-associated lymphoid tissue lymphoma 1 | 484
nasopharyngeal carcinoma 1 | 1,058
pediatric high grade glioma 1 | 1,064
posterior fossa group B ependymoma 1 | 416
progressive supranuclear palsy 1 | 676
severe Alzheimer's disease 1 | 47
sonic hedgehog group medulloblastoma 1 | 467
spina bifida 1 | 1,074

Tissue

Cardiovascular System 14 | 15,192
Digestive Tract 14 | 17,369
Endocrine System 14 | 18,159
Female tissues 14 | 17,400
Liver and Pancreas 14 | 16,750
Male tissues 14 | 17,142
Nervous System 14 | 16,725
Respiratory system 14 | 16,393
Skin and soft tissues 14 | 17,230
Urinary Tract 14 | 16,678
Blood and immune system 13 | 16,909

Target Family

Non-IDG 7 | 12,091
Enzyme 6 | 4,145
Kinase 1 | 634

GO Function

GTPase inhibitor activity 14 | 14
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Rhotekin RTKN Tbio Non-IDG -1.49615 24.3 137
Ras GTPase-activating-like protein IQGAP2 IQGAP2 Tbio Enzyme -1.40687 25.2 146
Cytoplasmic polyadenylation element-binding protein 2 CPEB2 Tbio Non-IDG -0.98921 8.38 85
Importin-5 IPO5 Tbio Non-IDG -2.18052 149.5 122
Diacylglycerol kinase iota DGKI Tbio Enzyme -0.89505 7.70 152
Ras GTPase-activating-like protein IQGAP1 IQGAP1 Tbio Enzyme -2.27732 224.8 291
Rho-related GTP-binding protein RhoH RHOH Tbio Enzyme -1.89296 87.5 181
COP9 signalosome complex subunit 1 GPS1 Tbio Non-IDG -1.62973 42.8 246
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta PDE6D Tclin Enzyme -1.48536 30.6 109
Slit homolog 2 protein SLIT2 Tbio Non-IDG -2.01765 104.0 215