Development Level

Tbio 10 | 10,625

IMPC Term

abnormal retina morphology 1 | 100
decreased circulating calcium ... 1 | 33
decreased circulating phosphat... 1 | 15
increased mean platelet volume 1 | 19
preweaning lethality, incomple... 1 | 260

Disease

medulloblastoma, large-cell 5 | 6,234
osteosarcoma 5 | 7,933
astrocytic glioma 4 | 2,241
glioblastoma 4 | 5,572
lung carcinoma 4 | 2,844
medulloblastoma 4 | 1,524
ovarian cancer 4 | 8,484
Breast cancer 3 | 3,094
Pick disease 3 | 1,893
atypical teratoid / rhabdoid tumor 3 | 4,369
ependymoma 3 | 2,514
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,988
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,289
lung cancer 3 | 4,466
oligodendroglioma 3 | 2,849
pediatric high grade glioma 3 | 2,712
pilocytic astrocytoma 3 | 3,086
primitive neuroectodermal tumor 3 | 3,031
Choroideremia 2 | 13
adult high grade glioma 2 | 2,148
ductal carcinoma in situ 2 | 1,745
esophageal adenocarcinoma 2 | 737
group 3 medulloblastoma 2 | 2,254
juvenile dermatomyositis 2 | 1,189
pancreatic cancer 2 | 2,300
pituitary cancer 2 | 1,972
posterior fossa group A ependymoma 2 | 1,511
primary pancreatic ductal adenocarcinoma 2 | 1,271
spina bifida 2 | 1,064
tuberculosis and treatment for 3 months 2 | 327
AMYOTROPHIC LATERAL SCLEROSIS 1 1 | 49
Alzheimer's disease 1 | 644
Amyotrophic lateral sclerosis type 1 1 | 15
Amyotrophic lateral sclerosis type 4 1 | 5
Atopic dermatitis 1 | 944
Becker muscular dystrophy 1 | 187
Blindness 1 | 84
Bone Diseases, Developmental 1 | 25
Cancer 1 | 2,346
Chromosomal duplication syndrome 1 | 2
Chudley-Mccullough syndrome 1 | 1
Cocaine-Related Disorders 1 | 88
Craniofacial Abnormalities 1 | 147
Crohn's disease 1 | 304
DiGeorge syndrome 1 | 46
Diabetes Mellitus, Non-Insulin-Dependent 1 | 157
Down syndrome 1 | 548
Duchenne muscular dystrophy 1 | 602
Gaucher disease type 1 1 | 171
HIV Infections 1 | 100
Inflammatory Bowel Diseases 1 | 87
Intellectual disability 1 | 573
Jensen syndrome 1 | 5
Keratitis 1 | 42
Kidney disease 1 | 396
Legionnaires' disease 1 | 20
MENTAL RETARDATION, X-LINKED 3 1 | 2
MENTAL RETARDATION, X-LINKED 41 1 | 1
Mental Retardation, X-Linked 1 | 22
Morphine dependence 1 | 19
Multiple Sclerosis 1 | 498
Nephrolithiasis 1 | 30
Night Blindness 1 | 39
Nonsyndromic deafness 1 | 121
Orofacial cleft 1 | 38
Parkinson's disease 1 | 364
Prostate carcinoma in situ 1 | 11
Pulmonary emphysema 1 | 34
Rheumatoid Arthritis 1 | 1,160
Tumor of exocrine pancreas 1 | 1
Usher syndrome 1 | 34
Velocardiofacial syndrome 1 | 45
Zellweger Syndrome 1 | 38
active ulcerative colitis 1 | 477
adrenocortical carcinoma 1 | 1,427
cutaneous lupus erythematosus 1 | 1,056
cystic fibrosis 1 | 1,665
dermatomyositis 1 | 933
diabetes mellitus 1 | 1,663
fascioscapulohumeral muscular dystrophy 1 | 100
gastric cancer 1 | 430
gastric carcinoma 1 | 832
interstitial cystitis 1 | 2,299
invasive ductal carcinoma 1 | 2,950
limb girdle muscular dystrophy 2I 1 | 56
non primary Sjogren syndrome sicca 1 | 840
non-small cell lung cancer 1 | 2,798
progressive supranuclear palsy 1 | 674
psoriasis 1 | 6,685
sonic hedgehog group medulloblastoma 1 | 1,482
tuberculosis 1 | 1,557

Tissue

Blood and immune system 10 | 17,995
Cardiovascular System 10 | 17,958
Digestive Tract 10 | 18,473
Endocrine System 10 | 18,512
Female tissues 10 | 18,647
Liver and Pancreas 10 | 18,136
Male tissues 10 | 17,969
Nervous System 10 | 18,561
Respiratory system 10 | 17,484
Skin and soft tissues 10 | 18,115
Urinary Tract 10 | 18,444

Target Family

Non-IDG 7 | 11,971
Enzyme 3 | 4,146

GO Function

GDP-dissociation inhibitor act... 10 | 10
metal ion binding 1,917 | 1,917
ATP binding 1,467 | 1,467
DNA binding 1,432 | 1,432
zinc ion binding 1,155 | 1,155
poly(A) RNA binding 1,107 | 1,107
transcription factor activity,... 853 | 853
calcium ion binding 695 | 695
G-protein coupled receptor act... 661 | 661
protein homodimerization activ... 569 | 569
RNA binding 445 | 445
olfactory receptor activity 424 | 424
sequence-specific DNA binding 398 | 398
GTP binding 374 | 374
chromatin binding 372 | 372
protein serine/threonine kinas... 336 | 336
RNA polymerase II core promote... 332 | 332
identical protein binding 311 | 311
nucleotide binding 311 | 311
receptor binding 303 | 303
protein kinase binding 289 | 289
enzyme binding 286 | 286
cadherin binding involved in c... 277 | 277
GTPase activator activity 273 | 273
ubiquitin protein ligase bindi... 258 | 258
ubiquitin-protein transferase ... 253 | 253
serine-type endopeptidase acti... 246 | 246
transcription coactivator acti... 241 | 241
transcription factor binding 240 | 240
structural molecule activity 232 | 232
GTPase activity 231 | 231
transcriptional activator acti... 230 | 230
ligase activity 227 | 227
protein heterodimerization act... 227 | 227
structural constituent of ribo... 212 | 212
transcription regulatory regio... 202 | 202
transmembrane signaling recept... 201 | 201
RNA polymerase II regulatory r... 200 | 200
receptor activity 200 | 200
transcription corepressor acti... 198 | 198
magnesium ion binding 197 | 197
signal transducer activity 196 | 196
nucleic acid binding 184 | 184
protein kinase activity 183 | 183
carbohydrate binding 180 | 180
ubiquitin protein ligase activ... 173 | 173
RNA polymerase II transcriptio... 162 | 162
heparin binding 160 | 160
iron ion binding 141 | 141
lipid binding 136 | 136
transporter activity 136 | 136
actin binding 133 | 133
ATPase activity 132 | 132
protein C-terminus binding 129 | 129
heme binding 127 | 127
microtubule binding 123 | 123
protein tyrosine kinase activi... 119 | 119
cytokine activity 118 | 118
Ras guanyl-nucleotide exchange... 113 | 113
mRNA binding 112 | 112
metalloendopeptidase activity 112 | 112
transcriptional repressor acti... 110 | 110
structural constituent of cyto... 108 | 108
Rab GTPase binding 105 | 105
antigen binding 104 | 104
protein domain specific bindin... 102 | 102
peptide antigen binding 101 | 101
guanyl-nucleotide exchange fac... 98 | 98
protein complex binding 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 92 | 92
oxidoreductase activity 91 | 91
transcriptional activator acti... 91 | 91
actin filament binding 89 | 89
hydrolase activity 89 | 89
ion channel binding 89 | 89
protein tyrosine phosphatase a... 88 | 88
electron carrier activity 87 | 87
protease binding 87 | 87
histone binding 86 | 86
integrin binding 83 | 83
growth factor activity 82 | 82
phospholipid binding 82 | 82
single-stranded DNA binding 81 | 81
unfolded protein binding 77 | 77
kinase activity 75 | 75
thiol-dependent ubiquitin-spec... 75 | 75
phosphatidylinositol binding 74 | 74
calmodulin binding 73 | 73
histone deacetylase binding 73 | 73
Rho guanyl-nucleotide exchange... 72 | 72
drug binding 71 | 71
double-stranded DNA binding 70 | 70
peptidase activity 70 | 70
protein N-terminus binding 70 | 70
virus receptor activity 68 | 68
beta-catenin binding 67 | 67
microtubule motor activity 67 | 67
protein transporter activity 67 | 67
calcium channel activity 66 | 66
ubiquitin binding 66 | 66

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
G-protein-signaling modulator 1 GPSM1 Tbio Non-IDG -1.32467 28.6 99
Sestrin-2 SESN2 Tbio Non-IDG -1.73062 73.0 151
Rab proteins geranylgeranyltransferase component A 1 CHM Tbio Enzyme -2.45284 282.4 87
Regulator of G-protein signaling 14 RGS14 Tbio Non-IDG -1.55181 40.9 217
Rab proteins geranylgeranyltransferase component A 2 CHML Tbio Enzyme -1.86194 70.4 110
Integrin beta-1-binding protein 1 ITGB1BP1 Tbio Non-IDG -1.20554 20.2 104
G-protein-signaling modulator 2 GPSM2 Tbio Non-IDG -2.85660 772.7 128
Rab GDP dissociation inhibitor alpha GDI1 Tbio Non-IDG -1.53240 34.5 210
SH3 domain-binding protein 4 SH3BP4 Tbio Non-IDG -0.62165 4.22 131
Ran-specific GTPase-activating protein RANBP1 Tbio Enzyme -1.78701 63.0 151