Development Level

Tdark 12 | 7,003
Tchem 8 | 1,890
Tclin 8 | 602

Collection

Eligible Ion Channel Proteins 3 | 117
Eligible non-olfactory GPCR Proteins 2 | 145

IMPC Term

abnormal behavioral response t... 2 | 52
cardiovascular system phenotyp... 1 | 35
decreased anxiety-related resp... 1 | 12
decreased total body fat amoun... 1 | 186
increased circulating sodium l... 1 | 71
increased lean body mass 1 | 107
increased mean corpuscular vol... 1 | 91
increased total body fat amoun... 1 | 57
preweaning lethality, complete... 1 | 633
preweaning lethality, incomple... 1 | 260
short tail 1 | 4

Disease

Migraine 12 | 79
Schizophrenia 10 | 503
Major Depressive Disorder 8 | 106
Alzheimer's disease 6 | 644
Autistic Disorder 6 | 320
psoriasis 6 | 6,685
Alcohol dependence 5 | 107
Amnestic disorder 5 | 37
Bipolar Disorder 5 | 266
Cluster headache syndrome 5 | 8
Irritable bowel syndrome 5 | 59
Parkinson's disease 5 | 364
Substance abuse 5 | 55
malignant mesothelioma 5 | 3,163
obsessive-compulsive disorder 5 | 34
Attention deficit hyperactivity disorder 4 | 156
Chemotherapy-induced nausea and vomiting 4 | 18
Dementia 4 | 129
Diabetic gastroparesis 4 | 7
Gastroesophageal reflux disease 4 | 37
Gastrointestinal Radiography Adjunct 4 | 11
Generalized anxiety disorder 4 | 29
Intubation of gastrointestinal tract 4 | 7
Obesity 4 | 616
Personality disorder 4 | 25
Prevention of Post-Operative Nausea and Vomiting 4 | 14
diabetes mellitus 4 | 1,663
medulloblastoma, large-cell 4 | 6,234
osteosarcoma 4 | 7,933
Bipolar affective disorder, current episode manic 3 | 13
Carcinoma 3 | 2,147
Cluster Headache Prevention 3 | 6
Cocaine-Related Disorders 3 | 88
Dyspepsia 3 | 34
Hypoactive sexual desire disorder 3 | 9
Memory Disorders 3 | 36
Migraine Prevention 3 | 22
Mixed bipolar I disorder 3 | 9
Panic disorder 3 | 55
Premature ejaculation 3 | 16
Vascular headache 3 | 6
ependymoma 3 | 2,514
glioblastoma 3 | 5,572
oligodendroglioma 3 | 2,849
primitive neuroectodermal tumor 3 | 3,031
Acromegaly 2 | 40
Agitation associated with Bipolar Mania 2 | 5
Agitation associated with Schizophrenia 2 | 5
Amphetamine-Related Disorders 2 | 74
Bipolar disorder in remission 2 | 19
Bruxism 2 | 19
Chronic thromboembolic pulmonary hypertension 2 | 4
Constipation 2 | 43
Depression Treatment Adjunct 2 | 5
Depressive disorder 2 | 48
Diarrhea 2 | 155
Drug psychosis 2 | 7
Eating disorder 2 | 24
Epilepsy 2 | 346
Fever 2 | 34
Gastroparesis 2 | 20
Heart disease 2 | 279
Hyperactive behavior 2 | 31
Hyperprolactinemia 2 | 22
Hypertension 2 | 293
Hypotension 2 | 53
Infantile autism 2 | 4
Lack or loss of sexual desire 2 | 3
Learning Disorders 2 | 27
Motion sickness 2 | 32
Neuroleptic malignant syndrome 2 | 8
Pain 2 | 70
Pain agnosia 2 | 99
Parkinsonism 2 | 19
Postabortal Hemorrhage 2 | 3
Postpartum hemorrhage 2 | 6
Psychoses, Substance-Induced 2 | 17
Psychotic Disorders 2 | 20
Schizoaffective disorder 2 | 33
Seasonal affective disorder 2 | 25
Seizures 2 | 95
Sexual dysfunction 2 | 10
Treatment-Resistant Schizophrenia 2 | 3
astrocytic glioma 2 | 2,241
medulloblastoma 2 | 1,524
non diabetic and post-ischemic heart failure 2 | 200
ovarian cancer 2 | 8,492
pediatric high grade glioma 2 | 2,712
pilocytic astrocytoma 2 | 3,086
post-traumatic stress disorder 2 | 45
pulmonary arterial hypertension 2 | 36
substance-related disorder 2 | 105
Alcoholic Intoxication, Chronic 1 | 41
Anorexia 1 | 15
Fibromyalgia 1 | 22
Gilles de la Tourette syndrome 1 | 47
Nasal congestion 1 | 24
Pulmonary hypertension 1 | 52
Sudden infant death syndrome 1 | 34
lingual-facial-buccal dyskinesia 1 | 10

Tissue

Female tissues 26 | 18,647
Urinary Tract 26 | 18,444
Digestive Tract 23 | 18,473
Endocrine System 23 | 18,512
Nervous System 23 | 18,561
Liver and Pancreas 21 | 18,136
Skin and soft tissues 20 | 18,115
Male tissues 16 | 17,969
Cardiovascular System 15 | 17,958
Respiratory system 13 | 17,484
Blood and immune system 12 | 17,995

Target Family

GPCR 12 | 408
oGPCR 12 | 421
Ion Channel 4 | 341

GO Function

G-protein coupled serotonin re... 28 | 28
metal ion binding 1,917 | 1,917
ATP binding 1,467 | 1,467
DNA binding 1,432 | 1,432
zinc ion binding 1,155 | 1,155
poly(A) RNA binding 1,107 | 1,107
transcription factor activity,... 853 | 853
calcium ion binding 695 | 695
G-protein coupled receptor act... 661 | 661
protein homodimerization activ... 569 | 569
RNA binding 445 | 445
olfactory receptor activity 424 | 424
sequence-specific DNA binding 398 | 398
GTP binding 374 | 374
chromatin binding 372 | 372
protein serine/threonine kinas... 336 | 336
RNA polymerase II core promote... 332 | 332
identical protein binding 311 | 311
nucleotide binding 311 | 311
receptor binding 303 | 303
protein kinase binding 289 | 289
enzyme binding 286 | 286
cadherin binding involved in c... 277 | 277
GTPase activator activity 273 | 273
ubiquitin protein ligase bindi... 258 | 258
ubiquitin-protein transferase ... 253 | 253
serine-type endopeptidase acti... 246 | 246
transcription coactivator acti... 241 | 241
transcription factor binding 240 | 240
structural molecule activity 232 | 232
GTPase activity 231 | 231
transcriptional activator acti... 230 | 230
ligase activity 227 | 227
protein heterodimerization act... 227 | 227
structural constituent of ribo... 212 | 212
transcription regulatory regio... 202 | 202
transmembrane signaling recept... 201 | 201
RNA polymerase II regulatory r... 200 | 200
receptor activity 200 | 200
transcription corepressor acti... 198 | 198
magnesium ion binding 197 | 197
signal transducer activity 196 | 196
nucleic acid binding 184 | 184
protein kinase activity 183 | 183
carbohydrate binding 180 | 180
ubiquitin protein ligase activ... 173 | 173
RNA polymerase II transcriptio... 162 | 162
heparin binding 160 | 160
iron ion binding 141 | 141
lipid binding 136 | 136
transporter activity 136 | 136
actin binding 133 | 133
ATPase activity 132 | 132
protein C-terminus binding 129 | 129
heme binding 127 | 127
microtubule binding 123 | 123
protein tyrosine kinase activi... 119 | 119
cytokine activity 118 | 118
Ras guanyl-nucleotide exchange... 113 | 113
mRNA binding 112 | 112
metalloendopeptidase activity 112 | 112
transcriptional repressor acti... 110 | 110
structural constituent of cyto... 108 | 108
Rab GTPase binding 105 | 105
antigen binding 104 | 104
protein domain specific bindin... 102 | 102
peptide antigen binding 101 | 101
guanyl-nucleotide exchange fac... 98 | 98
protein complex binding 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 92 | 92
oxidoreductase activity 91 | 91
transcriptional activator acti... 91 | 91
actin filament binding 89 | 89
hydrolase activity 89 | 89
ion channel binding 89 | 89
protein tyrosine phosphatase a... 88 | 88
electron carrier activity 87 | 87
protease binding 87 | 87
histone binding 86 | 86
integrin binding 83 | 83
growth factor activity 82 | 82
phospholipid binding 82 | 82
single-stranded DNA binding 81 | 81
unfolded protein binding 77 | 77
kinase activity 75 | 75
thiol-dependent ubiquitin-spec... 75 | 75
phosphatidylinositol binding 74 | 74
calmodulin binding 73 | 73
histone deacetylase binding 73 | 73
Rho guanyl-nucleotide exchange... 72 | 72
drug binding 71 | 71
double-stranded DNA binding 70 | 70
peptidase activity 70 | 70
protein N-terminus binding 70 | 70
virus receptor activity 68 | 68
beta-catenin binding 67 | 67
microtubule motor activity 67 | 67
protein transporter activity 67 | 67
calcium channel activity 66 | 66
ubiquitin binding 66 | 66

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
5-hydroxytryptamine receptor 1F HTR1F Tchem GPCR -2.37415 233.4 123
5-hydroxytryptamine receptor 3C HTR3C Tchem Ion Channel -0.65465 4.86 68
5-hydroxytryptamine receptor 4 HTR4 Tclin GPCR -2.86776 789.6 230
5-hydroxytryptamine receptor 2B HTR2B Tclin GPCR -2.65944 482.1 258
5-hydroxytryptamine receptor 2C HTR2C Tclin GPCR -3.07512 1179.6 312
5-hydroxytryptamine receptor 1E HTR1E Tchem GPCR -1.54352 34.9 99
Olfactory receptor 10H1 OR10H1 Tdark oGPCR 0.48 0.46 71
5-hydroxytryptamine receptor 6 HTR6 Tchem GPCR -2.29823 203.8 55
Olfactory receptor 11H4 OR11H4 Tdark oGPCR 0.00000 14
Olfactory receptor 11H7 OR11H7 Tdark oGPCR 0.00000 0