Development Level

Tdark 452 | 7,003
Tbio 121 | 10,625
Tchem 73 | 1,890
Tclin 15 | 602

Collection

Eligible non-olfactory GPCR Proteins 113 | 143

IMPC Term

decreased bone mineral density 6 | 126
hyperactivity 5 | 108
increased or absent threshold ... 5 | 128
decreased body weight 4 | 174
decreased lean body mass 4 | 195
abnormal behavior 3 | 226
decreased body length 3 | 108
decreased bone mineral content 3 | 157
enlarged heart 3 | 111
increased grip strength 3 | 83
preweaning lethality, complete... 3 | 633
abnormal bone mineralization 2 | 55
abnormal bone structure 2 | 131
abnormal epididymis morphology 2 | 31
abnormal gait 2 | 51
abnormal heart morphology 2 | 51
abnormal skin coloration 2 | 18
abnormal sleep behavior 2 | 63
decreased circulating HDL chol... 2 | 77
decreased circulating choleste... 2 | 85
decreased circulating glucose ... 2 | 121
decreased grip strength 2 | 123
decreased hemoglobin content 2 | 53
decreased leukocyte cell numbe... 2 | 54
decreased mean corpuscular hem... 2 | 34
decreased prepulse inhibition 2 | 52
decreased startle reflex 2 | 48
decreased total body fat amoun... 2 | 186
enlarged epididymis 2 | 27
impaired glucose tolerance 2 | 52
increased circulating HDL chol... 2 | 63
increased circulating calcium ... 2 | 32
increased circulating chloride... 2 | 43
increased circulating creatini... 2 | 29
increased erythrocyte cell num... 2 | 26
increased exploration in new e... 2 | 56
increased hematocrit 2 | 36
increased hemoglobin content 2 | 45
increased mean corpuscular vol... 2 | 91
preweaning lethality, incomple... 2 | 260
abnormal QRS complex 1 | 25
abnormal behavioral response t... 1 | 52
abnormal coping response 1 | 12
abnormal embryo turning 1 | 15
abnormal eye morphology 1 | 38
abnormal eye size 1 | 11
abnormal iris morphology 1 | 12
abnormal lens morphology 1 | 73
abnormal liver morphology 1 | 5
abnormal optic disc morphology 1 | 10
abnormal retina morphology 1 | 100
abnormal retinal pigmentation 1 | 61
abnormal skin morphology 1 | 23
abnormal startle reflex 1 | 14
absent startle reflex 1 | 15
cataract 1 | 26
decreased CD8-positive, alpha-... 1 | 26
decreased IgE level 1 | 3
decreased Ly6C high monocyte n... 1 | 18
decreased NK T cell number 1 | 28
decreased T cell number 1 | 31
decreased caudal vertebrae num... 1 | 49
decreased circulating iron lev... 1 | 25
decreased heart weight 1 | 44
decreased hematocrit 1 | 25
decreased mature B cell number 1 | 25
decreased mean corpuscular hem... 1 | 19
decreased mean corpuscular vol... 1 | 50
decreased monocyte cell number 1 | 28
decreased rib number 1 | 59
decreased vertical activity 1 | 22
embryonic lethality prior to t... 1 | 187
female infertility 1 | 34
hydrops fetalis 1 | 22
hypoactivity 1 | 89
increased NK cell number 1 | 19
increased blood urea nitrogen ... 1 | 44
increased body length 1 | 20
increased bone mineral density 1 | 52
increased caudal vertebrae num... 1 | 8
increased circulating alkaline... 1 | 119
increased circulating bilirubi... 1 | 16
increased circulating choleste... 1 | 53
increased circulating sodium l... 1 | 71
increased gamma-delta T cell n... 1 | 16
increased heart rate variabili... 1 | 4
increased heart weight 1 | 37
increased lean body mass 1 | 107
increased mean corpuscular hem... 1 | 93
increased total body fat amoun... 1 | 57
microphthalmia 1 | 15
mydriasis 1 | 9
oligodactyly 1 | 14
prenatal lethality 1 | 16
prenatal lethality prior to he... 1 | 64
short tibia 1 | 82
shortened PQ interval 1 | 6
small testis 1 | 37
thrombocytopenia 1 | 46
urinary bladder obstruction 1 | 2

Disease

psoriasis 104 | 6,685
diabetes mellitus 98 | 1,663
osteosarcoma 95 | 7,933
medulloblastoma, large-cell 87 | 6,234
ovarian cancer 85 | 8,484
glioblastoma 62 | 5,572
atypical teratoid / rhabdoid tumor 61 | 4,369
interstitial cystitis 57 | 2,299
lung carcinoma 53 | 2,844
lung cancer 45 | 4,466
Carcinoma 44 | 2,147
adult high grade glioma 41 | 2,148
lung adenocarcinoma 41 | 2,713
pilocytic astrocytoma 41 | 3,086
primitive neuroectodermal tumor 35 | 3,031
Breast cancer 34 | 3,094
intraductal papillary-mucinous neoplasm (IPMN) 34 | 3,289
intraductal papillary-mucinous adenoma (IPMA) 33 | 2,956
malignant mesothelioma 33 | 3,162
invasive ductal carcinoma 32 | 2,950
pediatric high grade glioma 32 | 2,712
ependymoma 31 | 2,514
pituitary cancer 31 | 1,972
ulcerative colitis 31 | 2,087
intraductal papillary-mucinous carcinoma (IPMC) 30 | 2,988
posterior fossa group A ependymoma 30 | 1,511
oligodendroglioma 29 | 2,849
breast carcinoma 27 | 1,614
ductal carcinoma in situ 27 | 1,745
non-small cell lung cancer 27 | 2,798
Cancer 26 | 2,346
pancreatic cancer 24 | 2,300
subependymal giant cell astrocytoma 24 | 2,287
sonic hedgehog group medulloblastoma 23 | 1,482
Schizophrenia 21 | 501
astrocytic glioma 21 | 2,241
cystic fibrosis 20 | 1,665
medulloblastoma 20 | 1,524
cutaneous lupus erythematosus 19 | 1,056
Pick disease 18 | 1,893
Obesity 17 | 616
primary Sjogren syndrome 17 | 789
group 3 medulloblastoma 16 | 2,254
group 4 medulloblastoma 16 | 1,875
tuberculosis 16 | 1,557
astrocytoma 15 | 1,493
colon cancer 15 | 1,475
gastric carcinoma 15 | 832
mucosa-associated lymphoid tissue lymphoma 15 | 480
Multiple Sclerosis 14 | 498
non-small cell lung carcinoma 14 | 413
Hemolytic anemia 13 | 66
adrenocortical carcinoma 13 | 1,427
pancreatic ductal adenocarcinoma liver metastasis 13 | 1,795
Atopic dermatitis 12 | 944
Rheumatoid Arthritis 12 | 1,160
atypical teratoid/rhabdoid tumor 12 | 1,095
primary pancreatic ductal adenocarcinoma 12 | 1,271
Epilepsy 11 | 346
esophageal adenocarcinoma 11 | 737
non primary Sjogren syndrome sicca 11 | 840
posterior fossa group B ependymoma 11 | 1,530
active Crohn's disease 10 | 918
juvenile dermatomyositis 10 | 1,189
fibroadenoma 9 | 557
Duchenne muscular dystrophy 8 | 602
acute myeloid leukemia 8 | 780
spina bifida 8 | 1,064
Acquired metabolic disease 7 | 267
Asthma 7 | 349
Cardiovascular system disease 7 | 194
Down syndrome 7 | 548
Pain agnosia 7 | 99
Alcohol dependence 6 | 107
Alzheimer's disease 6 | 644
Anorexia nervosa 6 | 59
Endometriosis 6 | 535
Epilepsy, Temporal Lobe 6 | 23
Inflammatory Bowel Diseases 6 | 87
Major Depressive Disorder 6 | 106
aldosterone-producing adenoma 6 | 664
autosomal dominant Emery-Dreifuss muscular dystrophy 6 | 499
chronic lymphosyte leukemia 6 | 232
glioblastoma multiforme 6 | 347
hepatocellular carcinoma 6 | 532
nasopharyngeal carcinoma 6 | 1,056
tuberculosis and treatment for 3 months 6 | 327
Attention deficit hyperactivity disorder 5 | 156
Chronic obstructive pulmonary disease 5 | 146
Mammary Neoplasms 5 | 410
Osteoporosis 5 | 257
Parkinson's disease 5 | 364
Retinitis pigmentosa 5 | 153
Waldenstrons macroglobulinemia 5 | 765
acute quadriplegic myopathy 5 | 1,157
facioscapulohumeral dystrophy 5 | 286
head and neck cancer 5 | 270
non diabetic and post-ischemic heart failure 5 | 200
non-inflammatory breast cancer 5 | 208
pancreatic carcinoma 5 | 567

Tissue

Female tissues 548 | 18,647
Urinary Tract 520 | 18,444
Nervous System 467 | 18,561
Endocrine System 466 | 18,512
Digestive Tract 438 | 18,473
Skin and soft tissues 407 | 18,115
Liver and Pancreas 339 | 18,136
Blood and immune system 326 | 17,995
Cardiovascular System 320 | 17,958
Male tissues 290 | 17,969
Respiratory system 262 | 17,484

Target Family

oGPCR 409 | 421
GPCR 235 | 406
Non-IDG 17 | 11,971

GO Function

G-protein coupled receptor act... 661 | 661
metal ion binding 1,917 | 1,917
ATP binding 1,467 | 1,467
DNA binding 1,432 | 1,432
zinc ion binding 1,155 | 1,155
poly(A) RNA binding 1,107 | 1,107
transcription factor activity,... 853 | 853
calcium ion binding 695 | 695
protein homodimerization activ... 569 | 569
RNA binding 445 | 445
olfactory receptor activity 424 | 424
sequence-specific DNA binding 398 | 398
GTP binding 374 | 374
chromatin binding 372 | 372
protein serine/threonine kinas... 336 | 336
RNA polymerase II core promote... 332 | 332
identical protein binding 311 | 311
nucleotide binding 311 | 311
receptor binding 303 | 303
protein kinase binding 289 | 289
enzyme binding 286 | 286
cadherin binding involved in c... 277 | 277
GTPase activator activity 273 | 273
ubiquitin protein ligase bindi... 258 | 258
ubiquitin-protein transferase ... 253 | 253
serine-type endopeptidase acti... 246 | 246
transcription coactivator acti... 241 | 241
transcription factor binding 240 | 240
structural molecule activity 232 | 232
GTPase activity 231 | 231
transcriptional activator acti... 230 | 230
ligase activity 227 | 227
protein heterodimerization act... 227 | 227
structural constituent of ribo... 212 | 212
transcription regulatory regio... 202 | 202
transmembrane signaling recept... 201 | 201
RNA polymerase II regulatory r... 200 | 200
receptor activity 200 | 200
transcription corepressor acti... 198 | 198
magnesium ion binding 197 | 197
signal transducer activity 196 | 196
nucleic acid binding 184 | 184
protein kinase activity 183 | 183
carbohydrate binding 180 | 180
ubiquitin protein ligase activ... 173 | 173
RNA polymerase II transcriptio... 162 | 162
heparin binding 160 | 160
iron ion binding 141 | 141
lipid binding 136 | 136
transporter activity 136 | 136
actin binding 133 | 133
ATPase activity 132 | 132
protein C-terminus binding 129 | 129
heme binding 127 | 127
microtubule binding 123 | 123
protein tyrosine kinase activi... 119 | 119
cytokine activity 118 | 118
Ras guanyl-nucleotide exchange... 113 | 113
mRNA binding 112 | 112
metalloendopeptidase activity 112 | 112
transcriptional repressor acti... 110 | 110
structural constituent of cyto... 108 | 108
Rab GTPase binding 105 | 105
antigen binding 104 | 104
protein domain specific bindin... 102 | 102
peptide antigen binding 101 | 101
guanyl-nucleotide exchange fac... 98 | 98
protein complex binding 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 92 | 92
oxidoreductase activity 91 | 91
transcriptional activator acti... 91 | 91
actin filament binding 89 | 89
hydrolase activity 89 | 89
ion channel binding 89 | 89
protein tyrosine phosphatase a... 88 | 88
electron carrier activity 87 | 87
protease binding 87 | 87
histone binding 86 | 86
integrin binding 83 | 83
growth factor activity 82 | 82
phospholipid binding 82 | 82
single-stranded DNA binding 81 | 81
unfolded protein binding 77 | 77
kinase activity 75 | 75
thiol-dependent ubiquitin-spec... 75 | 75
phosphatidylinositol binding 74 | 74
calmodulin binding 73 | 73
histone deacetylase binding 73 | 73
Rho guanyl-nucleotide exchange... 72 | 72
drug binding 71 | 71
double-stranded DNA binding 70 | 70
peptidase activity 70 | 70
protein N-terminus binding 70 | 70
virus receptor activity 68 | 68
beta-catenin binding 67 | 67
microtubule motor activity 67 | 67
protein transporter activity 67 | 67
calcium channel activity 66 | 66
ubiquitin binding 66 | 66

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Taste receptor type 1 member 3 TAS1R3 Tbio GPCR -2.19758 165.4 232
Taste receptor type 1 member 1 TAS1R1 Tbio GPCR -1.71516 50.8 165
Pro-neuropeptide Y NPY Tbio Non-IDG -3.81741 7285.3 401
Olfactory receptor 2T1 OR2T1 Tdark oGPCR 0.00000 38
LanC-like protein 1 LANCL1 Tbio Non-IDG -1.03436 11.5 49
Probable G-protein coupled receptor 83 GPR83 Tbio GPCR -2.32512 206.7 255
G-protein coupled receptor 26 GPR26 Tbio GPCR -0.57545 4.04 88
Adhesion G protein-coupled receptor A3 ADGRA3 Tbio GPCR -0.92696 10.7 107
Olfactory receptor 6B2 OR6B2 Tdark oGPCR 0.00000 1.00 64
Olfactory receptor 13A1 OR13A1 Tdark oGPCR 0.00000 2