Development Level

Tclin 4 | 613
Tchem 1 | 1,598

IMPC Phenotype

convulsive seizures 1 | 13
increased fasted circulating g... 1 | 76
preweaning lethality, incomple... 1 | 499

Disease

Acute exacerbation of asthma 4 | 14
Allergic rhinitis 4 | 94
Asthma 4 | 385
Asthma management 4 | 19
Asthma night-time symptoms 4 | 7
Asthma-chronic obstructive pulmonary disease overlap syndrome 4 | 7
Bronchitis 4 | 43
Bronchospasm 4 | 9
COPD Associated with Chronic Bronchitis 4 | 11
Carcinoma 4 | 11,493
Chronic Obstructive Pulmonary Disease with Bronchospasms 4 | 8
Common cold 4 | 67
Disorder of lung 4 | 7
Dysmenorrhea 4 | 21
Influenza-like symptoms 4 | 16
Nasal congestion 4 | 21
Nasal discharge 4 | 24
Pain 4 | 103
Pulmonary emphysema 4 | 48
Sinus headache 4 | 16
Spasticity 4 | 26
Vascular disease 4 | 319
Apnea in the newborn 3 | 3
Backache 3 | 8
Cluster Headache Prevention 3 | 6
Cluster headache syndrome 3 | 8
Headache disorder 3 | 19
Joint pain 3 | 8
Migraine 3 | 83
Myocardial Infarction 3 | 151
Myocardial Perfusion Imaging Adjunct 3 | 25
Paroxysmal supraventricular tachycardia 3 | 12
Tension-type headache 3 | 10
Vascular headache 3 | 7
group 3 medulloblastoma 3 | 4,104
medulloblastoma, large-cell 3 | 6,241
Adverse reaction to drug 2 | 61
Astrocytoma, Pilocytic 2 | 3,081
Depressive disorder 2 | 409
Drug Hypersensitivity 2 | 34
Drug allergy 2 | 36
Drug-Related Side Effects and Adverse Reactions 2 | 62
Epilepsy 2 | 792
Genetic Predisposition to Disease 2 | 27
Hypotension 2 | 82
Ischemia 2 | 28
Liver Cirrhosis, Experimental 2 | 769
Peripheral vascular disease 2 | 87
Reperfusion Injury 2 | 86
Schizophrenia 2 | 1,160
Sepsis 2 | 24
Substance Withdrawal Syndrome 2 | 55
Ventricular Dysfunction 2 | 7
adrenocortical carcinoma 2 | 1,428
astrocytic glioma 2 | 2,597
atypical teratoid / rhabdoid tumor 2 | 5,112
invasive ductal carcinoma 2 | 2,951
non-small cell lung cancer 2 | 2,890
pancreatic cancer 2 | 2,398
primitive neuroectodermal tumor 2 | 3,035
tuberculosis 2 | 2,010
Acute coronary syndrome 1 | 39
Alcohol withdrawal delirium 1 | 11
Alcohol withdrawal syndrome 1 | 20
Allergic conjunctivitis 1 | 22
Angina Pectoris 1 | 32
Anxiety 1 | 136
Anxiety Disorders 1 | 38
Bradycardia 1 | 36
Cardiomyopathies 1 | 110
Catalepsy 1 | 15
Cerebral embolism 1 | 3
Hemorrhage 1 | 19
Hyperactive behavior 1 | 91
Hyperkinesis 1 | 32
Hypertensive disorder 1 | 56
Induce Anterograde Amnesia 1 | 9
Infarction, Middle Cerebral Artery 1 | 33
Ischemic Attack, Transient 1 | 10
Limb ischemia 1 | 15
Lupus Erythematosus, Systemic 1 | 67
Neoplasm Metastasis 1 | 168
Nerve Degeneration 1 | 121
Non-Q wave myocardial infarction 1 | 4
Panic disorder 1 | 61
Peptic Ulcer 1 | 27
Peripheral artery disease 1 | 10
Preoperative Anxiety 1 | 9
Prevention of Cerebral Thrombosis 1 | 29
Psychoses, Substance-Induced 1 | 17
Sedation 1 | 11
Sleep Initiation and Maintenance Disorders 1 | 4
Subarachnoid Hemorrhage 1 | 7
Tetanus 1 | 68
Thrombosis 1 | 46
Transient Cerebral Ischemia 1 | 25
Transient Ischemic Attack 1 | 10
Vasomotor rhinitis 1 | 12
Weight Loss 1 | 24
sarcoidosis 1 | 370

Tissue

Blood and immune system 5 | 16,909
Cardiovascular System 5 | 15,192
Digestive Tract 5 | 17,369
Endocrine System 5 | 18,159
Female tissues 5 | 17,400
Liver and Pancreas 5 | 16,750
Male tissues 5 | 17,142
Nervous System 5 | 16,725
Respiratory system 5 | 16,393
Skin and soft tissues 5 | 17,230
Urinary Tract 5 | 16,678

Target Family

GPCR 5 | 408

GO Function

G-protein coupled adenosine re... 5 | 5
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Adenosine receptor A1 ADORA1 Tclin GPCR -3.08657 1177.9 342
Adenosine receptor A3 ADORA3 Tchem GPCR -2.39734 255.0 54
Adenosine receptor A2b ADORA2B Tclin GPCR -2.05073 105.4 198
Adenosine receptor A2a ADORA2A Tclin GPCR -2.98333 954.1 244
P2Y purinoceptor 12 P2RY12 Tclin GPCR -3.19274 1507.4 135