Development Level

Tbio 20 | 11,445
Tclin 1 | 613

IMPC Phenotype

increased startle reflex 3 | 112
preweaning lethality, complete... 3 | 979
abnormal behavior 2 | 298
abnormal bone structure 2 | 187
increased heart weight 2 | 62
abnormal spleen morphology 1 | 55
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased circulating amylase ... 1 | 28
decreased circulating iron lev... 1 | 32
decreased circulating phosphat... 1 | 27
decreased circulating total pr... 1 | 49
decreased circulating triglyce... 1 | 79
decreased erythrocyte cell num... 1 | 62
decreased fasted circulating g... 1 | 65
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased prepulse inhibition 1 | 82
decreased respiratory quotient 1 | 16
decreased startle reflex 1 | 75
hyperactivity 1 | 148
impaired righting response 1 | 26
increased circulating calcium ... 1 | 34
increased circulating creatini... 1 | 38
increased circulating triglyce... 1 | 42
increased fasted circulating g... 1 | 76
short tibia 1 | 97
vertebral fusion 1 | 23

Disease

Carcinoma 17 | 11,493
medulloblastoma, large-cell 13 | 6,241
ovarian cancer 12 | 8,520
atypical teratoid / rhabdoid tumor 10 | 5,112
osteosarcoma 10 | 7,950
psoriasis 9 | 6,694
ependymoma 8 | 4,679
glioblastoma 8 | 5,792
group 3 medulloblastoma 8 | 4,104
colon cancer 7 | 1,478
adult high grade glioma 6 | 3,801
astrocytic glioma 6 | 2,597
lung cancer 6 | 4,740
oligodendroglioma 6 | 2,850
primitive neuroectodermal tumor 6 | 3,035
ulcerative colitis 6 | 1,819
Breast cancer 5 | 3,578
Cancer 5 | 2,499
Substance Withdrawal Syndrome 5 | 55
lung carcinoma 5 | 2,843
pancreatic cancer 5 | 2,398
subependymal giant cell astrocytoma 5 | 2,287
Fibrous dysplasia 4 | 15
McCune Albright syndrome 4 | 19
Pick disease 4 | 1,894
Pseudohypoparathyroidism 4 | 18
Schizophrenia 4 | 1,160
breast carcinoma 4 | 1,638
invasive ductal carcinoma 4 | 2,951
pituitary cancer 4 | 1,972
ACTH-secreting pituitary adenoma 3 | 9
Astrocytoma, Pilocytic 3 | 3,081
Autosomal recessive predisposition 3 | 1,442
Cholera 3 | 34
Epilepsy 3 | 792
Polycystic ovary syndrome 3 | 360
astrocytoma 3 | 1,146
juvenile dermatomyositis 3 | 1,187
non-small cell lung cancer 3 | 2,890
tuberculosis 3 | 2,010
Abnormal vision 2 | 52
Acromegaly 2 | 51
Adenoma 2 | 167
Adrenal gland cancer 2 | 12
Amnesia 2 | 17
Big calvaria 2 | 147
Biliary tract cancer 2 | 19
Bone cancer 2 | 16
Brachydactyly 2 | 156
Bradycardia 2 | 36
Carney complex 2 | 25
Cerebral atrophy 2 | 178
Cervix carcinoma 2 | 10
Charcot-Marie-Tooth disease dominant intermediate F 2 | 3
Congenital Heart Defects 2 | 58
Cushing's syndrome 2 | 48
DOID:2415 2 | 5
Fibrodysplasia ossificans progressiva 2 | 17
Heart Defects, Congenital 2 | 37
Hyperphosphatemia 2 | 32
Hyperthyroidism 2 | 53
Hypoparathyroidism 2 | 41
Hypotension 2 | 82
Hypothyroidism 2 | 122
Increased head circumference 2 | 147
Increased size of cranium 2 | 147
Increased size of skull 2 | 147
Kidney cancer 2 | 2,613
Kidney disease 2 | 430
Liver Cirrhosis, Experimental 2 | 769
Liver cancer 2 | 604
Malignant melanoma of choroid 2 | 3
Malignant melanoma of ciliary body 2 | 3
Malignant melanoma of iris 2 | 4
Melanoma 2 | 711
Multiple Endocrine Neoplasia Type 1 2 | 29
Ocular cancer 2 | 7
Ossifying fibroma 2 | 15
Pertussis 2 | 20
Phakomatosis cesioflammea 2 | 2
Pituitary adenoma 2 | 38
Plummer's disease 2 | 11
Primary pigmented nodular adrenocortical disease 2 | 13
Retinal Detachment 2 | 51
Skin cancer 2 | 469
Small intestine cancer 2 | 12
Stomach cancer 2 | 30
Thyroid cancer 2 | 36
Uveal melanoma 2 | 20
active Crohn's disease 2 | 922
active ulcerative colitis 2 | 764
acute quadriplegic myopathy 2 | 1,158
dermatomyositis 2 | 966
lung adenocarcinoma 2 | 2,716
nasopharyngeal carcinoma 2 | 1,058
pediatric high grade glioma 2 | 1,064
primary Sjogren syndrome 2 | 735
spina bifida 2 | 1,074
substance-related disorder 2 | 162
urothelial carcinoma 2 | 318

Tissue

Endocrine System 19 | 18,159
Digestive Tract 18 | 17,369
Male tissues 17 | 17,142
Nervous System 17 | 16,725
Skin and soft tissues 17 | 17,230
Blood and immune system 16 | 16,909
Female tissues 16 | 17,400
Liver and Pancreas 16 | 16,750
Respiratory system 16 | 16,393
Cardiovascular System 15 | 15,192
Urinary Tract 15 | 16,678

Target Family

Non-IDG 19 | 12,091
Enzyme 1 | 4,145
GPCR 1 | 408

GO Function

G-protein beta-gamma-subunit c... 21 | 21
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Guanine nucleotide-binding protein subunit alpha-11 GNA11 Tbio Non-IDG -2.80484 555.1 184
Guanine nucleotide-binding protein subunit alpha-14 GNA14 Tbio Non-IDG -0.78609 4.51 142
Guanine nucleotide-binding protein G(q) subunit alpha GNAQ Tbio Non-IDG -2.73429 514.5 206
Guanine nucleotide-binding protein G(t) subunit alpha-3 GNAT3 Tbio Non-IDG -2.28370 189.3 111
Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas GNAS Tbio Non-IDG -2.63356 1389.7 509
Guanine nucleotide-binding protein G(o) subunit alpha GNAO1 Tbio Non-IDG -2.24331 158.7 195
Guanine nucleotide-binding protein subunit alpha-12 GNA12 Tbio Non-IDG -0.97325 9.11 163
Adenosine receptor A1 ADORA1 Tclin GPCR -3.08657 1177.9 342
Guanine nucleotide-binding protein G(olf) subunit alpha GNAL Tbio Non-IDG -1.49178 31.9 92
Centrin-1 CETN1 Tbio Non-IDG -1.86026 65.5 131