Development Level

Tbio 4 | 11,445
Tdark 1 | 6,588

IMPC Phenotype

decreased grip strength 1 | 116

Disease

Carcinoma 3 | 11,493
Cardiomyopathy 3 | 116
Hypertrophic Cardiomyopathy 3 | 117
Myopathy 3 | 185
acute quadriplegic myopathy 3 | 1,158
malignant mesothelioma 3 | 3,232
medulloblastoma, large-cell 3 | 6,241
Astrocytoma, Pilocytic 2 | 3,081
Cardiomyopathy, Dilated 2 | 83
Dilated cardiomyopathy 2 | 56
Familial isolated dilated cardiomyopathy 2 | 41
LEFT VENTRICULAR NONCOMPACTION 10 2 | 40
LEFT VENTRICULAR NONCOMPACTION 8 2 | 40
atypical teratoid / rhabdoid tumor 2 | 5,112
glioblastoma 2 | 5,792
lung adenocarcinoma 2 | 2,716
osteosarcoma 2 | 7,950
primitive neuroectodermal tumor 2 | 3,035
Areflexia of lower limbs 1 | 9
Atrial Fibrillation 1 | 124
Autosomal recessive predisposition 1 | 1,442
CARDIOMYOPATHY, DILATED, 1N 1 | 1
CARDIOMYOPATHY, FAMILIAL HYPERTROPHIC, 16 1 | 1
CARDIOMYOPATHY, FAMILIAL HYPERTROPHIC, 25 1 | 1
Calf muscle hypertrophy 1 | 9
Cancer 1 | 2,499
Cardiomyopathy, Dilated, 1AA 1 | 1
Cerebrovascular disease 1 | 238
Chronic obstructive pulmonary disease 1 | 184
Creatine phosphokinase serum increased 1 | 110
Diabetic retinopathy 1 | 56
Difficulty running 1 | 7
Difficulty walking 1 | 28
Difficulty walking up stairs 1 | 12
Distal lower limb muscle weakness 1 | 6
Elevated creatine kinase 1 | 110
Endocardial Fibroelastosis 1 | 9
Endomyocardial Fibrosis 1 | 13
Foot dorsiflexor weakness 1 | 27
Foot-drop 1 | 27
Heart disease 1 | 306
Highly variable clinical phenotype 1 | 150
Highly variable phenotype and severity 1 | 150
Highly variable phenotype, even within families 1 | 150
Hypertrichotic osteochondrodysplasia Cantu type 1 | 5
Increased connective tissue 1 | 7
Infantile onset spinocerebellar ataxia 1 | 7
Kidney cancer 1 | 2,613
Left Ventricular Hypertrophy 1 | 47
Lower limb atrophy 1 | 8
Lower limb muscle hypotrophy 1 | 8
Muscle atrophy, lower limb, distal 1 | 8
Muscle biopsy shows dystrophic changes 1 | 39
Muscular Dystrophy, Limb-Girdle, Type 2G 1 | 1
Muscular dystrophy 1 | 75
Myocardial Infarction 1 | 151
Myringitis bullosa hemorrhagica 1 | 1
Phenotypic variability 1 | 150
Pick disease 1 | 1,894
Proximal muscle atrophy in upper limbs 1 | 2
Proximal muscle weakness in upper limbs 1 | 2
Retinopathy of prematurity 1 | 22
Rimmed vacuoles on biopsy 1 | 15
Variation in muscle fiber size 1 | 16
adult high grade glioma 1 | 3,801
astrocytoma 1 | 1,146
dermatomyositis 1 | 966
dilated cardiomyopathy 1AA 1 | 1
ependymoma 1 | 4,679
group 3 medulloblastoma 1 | 4,104
group 4 medulloblastoma 1 | 1,855
hypertrophic cardiomyopathy 16 1 | 1
hypertrophic cardiomyopathy 25 1 | 1
juvenile dermatomyositis 1 | 1,187
limb-girdle muscular dystrophy 1 | 37
lung cancer 1 | 4,740
nephrosclerosis 1 | 333
non-small cell lung carcinoma 1 | 317
ovarian cancer 1 | 8,520
pediatric high grade glioma 1 | 1,064
psoriasis 1 | 6,694

Tissue

Blood and immune system 5 | 16,909
Cardiovascular System 5 | 15,192
Digestive Tract 5 | 17,369
Endocrine System 5 | 18,159
Female tissues 5 | 17,400
Liver and Pancreas 5 | 16,750
Male tissues 5 | 17,142
Nervous System 5 | 16,725
Respiratory system 5 | 16,393
Skin and soft tissues 5 | 17,230
Urinary Tract 5 | 16,678

Target Family

Non-IDG 5 | 12,091

GO Function

FATZ binding 5 | 5
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Myozenin-2 MYOZ2 Tbio Non-IDG -1.18586 15.9 124
Myozenin-1 MYOZ1 Tbio Non-IDG -1.23648 17.8 149
Myozenin-3 MYOZ3 Tdark Non-IDG -0.39925 2.96 19
Telethonin TCAP Tbio Non-IDG -3.33021 2076.3 97
Alpha-actinin-2 ACTN2 Tbio Non-IDG -1.89804 72.9 245