Development Level

Tbio 13 | 10,625
Tchem 4 | 1,890
Tdark 3 | 7,003

IMPC Phenotype

abnormal embryo size 2 | 112
abnormal coat-hair pigmentatio... 1 | 54
abnormal embryo turning 1 | 15
abnormal epididymis morphology 1 | 31
abnormal eye morphology 1 | 38
abnormal eye size 1 | 11
abnormal jejunum morphology 1 | 1
abnormal lung morphology 1 | 15
abnormal neural tube closure 1 | 37
abnormal skin appearance 1 | 8
abnormal tail bud morphology 1 | 6
abnormal testis morphology 1 | 30
abnormal vitreous body morphol... 1 | 7
abnormal vocalization 1 | 21
anophthalmia 1 | 20
craniofacial phenotype 1 | 9
decreased circulating alkaline... 1 | 41
decreased circulating calcium ... 1 | 33
embryonic growth retardation 1 | 28
embryonic lethality prior to o... 1 | 148
embryonic lethality prior to t... 1 | 187
enlarged lymph nodes 1 | 27
hydrops fetalis 1 | 22
increased circulating sodium l... 1 | 71
increased mean corpuscular hem... 1 | 93
microphthalmia 1 | 15
persistence of hyaloid vascula... 1 | 22
polycystic kidney 1 | 9
preweaning lethality, complete... 1 | 633
short tibia 1 | 82
small kidney 1 | 10

Disease

glioblastoma 11 | 5,572
osteosarcoma 9 | 7,933
lung cancer 8 | 4,473
medulloblastoma, large-cell 8 | 6,234
ovarian cancer 7 | 8,491
malignant mesothelioma 6 | 3,163
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,795
pilocytic astrocytoma 6 | 3,086
psoriasis 6 | 6,685
subependymal giant cell astrocytoma 6 | 2,287
atypical teratoid / rhabdoid tumor 5 | 4,369
oligodendroglioma 5 | 2,849
pediatric high grade glioma 5 | 2,712
primitive neuroectodermal tumor 5 | 3,031
Methemoglobinemia 4 | 17
ductal carcinoma in situ 4 | 1,745
interstitial cystitis 4 | 2,299
invasive ductal carcinoma 4 | 2,950
lung carcinoma 4 | 2,844
non-small cell lung cancer 4 | 2,798
sonic hedgehog group medulloblastoma 4 | 1,482
spina bifida 4 | 1,064
IGA Glomerulonephritis 3 | 454
Pick disease 3 | 1,893
Schizophrenia 3 | 503
astrocytoma 3 | 1,493
breast carcinoma 3 | 1,614
cutaneous lupus erythematosus 3 | 1,056
ependymoma 3 | 2,514
gastric carcinoma 3 | 832
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,956
posterior fossa group B ependymoma 3 | 1,530
Breast cancer 2 | 3,098
Diabetes Mellitus, Experimental 2 | 106
Down syndrome 2 | 548
Homocystinuria 2 | 23
Hyperhomocysteinemia 2 | 34
Methylmalonic acidemia 2 | 39
Monkeypox 2 | 10
Obesity 2 | 616
Rheumatoid Arthritis 2 | 1,170
Rhizomelic chondrodysplasia punctata 2 | 11
Smallpox 2 | 20
Vaccinia 2 | 37
Velocardiofacial syndrome 2 | 45
adult high grade glioma 2 | 2,148
astrocytic glioma 2 | 2,241
group 4 medulloblastoma 2 | 1,875
inflammatory breast cancer 2 | 404
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,289
lung adenocarcinoma 2 | 2,714
medulloblastoma 2 | 1,524
nervous system disorder 2 | 53
non primary Sjogren syndrome sicca 2 | 840
pancreatic cancer 2 | 2,300
pancreatic carcinoma 2 | 567
posterior fossa group A ependymoma 2 | 1,511
primary Sjogren syndrome 2 | 788
progressive supranuclear palsy 2 | 674
ulcerative colitis 2 | 2,087
Acquired immunodeficiency syndrome 1 | 164
Acquired metabolic disease 1 | 267
Adenoma 1 | 165
Adrenoleukodystrophy 1 | 31
Adverse reaction to drug 1 | 54
Amyotrophic Lateral Sclerosis 1 | 432
Autistic Disorder 1 | 320
Azoospermia 1 | 89
Basal cell carcinoma 1 | 31
Bipolar Disorder 1 | 266
COPD 1 | 116
Cataract 1 | 104
Charcot-Marie-Tooth disease 1 | 74
Chondrodysplasia punctata 1 | 41
Cleft Lip 1 | 91
Colorectal Neoplasms 1 | 217
Contagious pustular dermatitis 1 | 12
Diabetes Mellitus, Insulin-Dependent 1 | 77
Drug-Induced Liver Injury 1 | 118
Fatty liver disease 1 | 86
Fungal meningitis 1 | 7
Gastrointestinal Stromal Tumors 1 | 8
Huntington disease 1 | 12
Huntington's disease 1 | 72
Liver carcinoma 1 | 217
Multiple acyl-CoA dehydrogenase deficiency 1 | 26
Narcolepsy 1 | 69
Necrosis 1 | 51
Neural tube defect, folate-sensitive 1 | 4
Neural tube defects, folate-sensitive 1 | 4
Neurodegenerative disease 1 | 383
Neuropathy 1 | 210
Schizoaffective disorder 1 | 33
Vitamin B12 deficiency 1 | 20
Zellweger Syndrome 1 | 38
chronic kidney disease 1 | 90
head and neck cancer and chronic obstructive pulmonary disease 1 | 237
sarcoidosis 1 | 368
systemic lupus erythematosus 1 | 172
uncontrolled asthma 1 | 67

Tissue

Blood and immune system 20 | 17,994
Cardiovascular System 20 | 17,957
Digestive Tract 20 | 18,472
Endocrine System 20 | 18,511
Female tissues 20 | 18,646
Liver and Pancreas 20 | 18,135
Male tissues 20 | 17,968
Nervous System 20 | 18,560
Respiratory system 20 | 17,483
Skin and soft tissues 20 | 18,114
Urinary Tract 20 | 18,443

Target Family

Enzyme 17 | 4,146
Non-IDG 3 | 11,969

GO Function

FAD binding 20 | 20
metal ion binding 1,917 | 1,917
ATP binding 1,467 | 1,467
DNA binding 1,432 | 1,432
zinc ion binding 1,155 | 1,155
poly(A) RNA binding 1,107 | 1,107
transcription factor activity,... 853 | 853
calcium ion binding 695 | 695
G-protein coupled receptor act... 661 | 661
protein homodimerization activ... 569 | 569
RNA binding 445 | 445
olfactory receptor activity 424 | 424
sequence-specific DNA binding 398 | 398
GTP binding 374 | 374
chromatin binding 372 | 372
protein serine-threonine kinas... 336 | 336
RNA polymerase II core promote... 332 | 332
identical protein binding 311 | 311
nucleotide binding 311 | 311
receptor binding 303 | 303
protein kinase binding 289 | 289
enzyme binding 286 | 286
cadherin binding involved in c... 277 | 277
GTPase activator activity 273 | 273
ubiquitin protein ligase bindi... 258 | 258
ubiquitin-protein transferase ... 253 | 253
serine-type endopeptidase acti... 246 | 246
transcription coactivator acti... 241 | 241
transcription factor binding 240 | 240
structural molecule activity 232 | 232
GTPase activity 231 | 231
transcriptional activator acti... 230 | 230
ligase activity 227 | 227
protein heterodimerization act... 227 | 227
structural constituent of ribo... 212 | 212
transcription regulatory regio... 202 | 202
transmembrane signaling recept... 201 | 201
RNA polymerase II regulatory r... 200 | 200
receptor activity 200 | 200
transcription corepressor acti... 198 | 198
magnesium ion binding 197 | 197
signal transducer activity 196 | 196
nucleic acid binding 184 | 184
protein kinase activity 183 | 183
carbohydrate binding 180 | 180
ubiquitin protein ligase activ... 173 | 173
RNA polymerase II transcriptio... 162 | 162
heparin binding 160 | 160
iron ion binding 141 | 141
lipid binding 136 | 136
transporter activity 136 | 136
actin binding 133 | 133
ATPase activity 132 | 132
protein C-terminus binding 129 | 129
heme binding 127 | 127
microtubule binding 123 | 123
protein tyrosine kinase activi... 119 | 119
cytokine activity 118 | 118
Ras guanyl-nucleotide exchange... 113 | 113
mRNA binding 112 | 112
metalloendopeptidase activity 112 | 112
transcriptional repressor acti... 110 | 110
structural constituent of cyto... 108 | 108
Rab GTPase binding 105 | 105
antigen binding 104 | 104
protein domain specific bindin... 102 | 102
peptide antigen binding 101 | 101
guanyl-nucleotide exchange fac... 98 | 98
protein complex binding 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 92 | 92
oxidoreductase activity 91 | 91
transcriptional activator acti... 91 | 91
actin filament binding 89 | 89
hydrolase activity 89 | 89
ion channel binding 89 | 89
protein tyrosine phosphatase a... 88 | 88
electron carrier activity 87 | 87
protease binding 87 | 87
histone binding 86 | 86
integrin binding 83 | 83
growth factor activity 82 | 82
phospholipid binding 82 | 82
single-stranded DNA binding 81 | 81
unfolded protein binding 77 | 77
kinase activity 75 | 75
thiol-dependent ubiquitin-spec... 75 | 75
phosphatidylinositol binding 74 | 74
calmodulin binding 73 | 73
histone deacetylase binding 73 | 73
Rho guanyl-nucleotide exchange... 72 | 72
drug binding 71 | 71
double-stranded DNA binding 70 | 70
peptidase activity 70 | 70
protein N-terminus binding 70 | 70
virus receptor activity 68 | 68
beta-catenin binding 67 | 67
microtubule motor activity 67 | 67
protein transporter activity 67 | 67
calcium channel activity 66 | 66
ubiquitin binding 66 | 66

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Methylmalonic aciduria and homocystinuria type C protein MMACHC Tbio Non-IDG -1.77493 67.0 130
Proline dehydrogenase 1, mitochondrial PRODH Tbio Enzyme -2.85387 715.1 193
Protein-methionine sulfoxide oxidase MICAL2 MICAL2 Tbio Enzyme -0.38705 3.11 47
Protein-methionine sulfoxide oxidase MICAL3 MICAL3 Tdark Enzyme -0.73631 4.79 16
NADH-cytochrome b5 reductase 3 CYB5R3 Tchem Enzyme -1.92572 89.2 241
D-amino-acid oxidase DAO Tchem Enzyme -2.41089 256.4 191
Kynurenine 3-monooxygenase KMO Tchem Enzyme -2.08451 104.9 101
Cryptochrome-2 CRY2 Tbio Non-IDG -2.35140 215.9 131
Alkyldihydroxyacetonephosphate synthase, peroxisomal AGPS Tbio Enzyme -2.79749 606.8 73
Peroxisomal acyl-coenzyme A oxidase 1 ACOX1 Tbio Enzyme -2.05270 105.6 241