Development Level

Tbio 18 | 10,625
Tdark 4 | 7,003
Tchem 3 | 1,890
Tclin 3 | 602

IMPC Term

preweaning lethality, complete... 5 | 633
abnormal QRS complex 1 | 25
abnormal retinal pigmentation 1 | 61
decreased CD4-positive, CD25-p... 1 | 24
decreased circulating aspartat... 1 | 27
decreased heart left ventricle... 1 | 2
embryonic lethality prior to o... 1 | 148
increased circulating HDL chol... 1 | 63
increased circulating aspartat... 1 | 17
increased circulating choleste... 1 | 53
increased circulating sodium l... 1 | 71
male infertility 1 | 62
polydactyly 1 | 22
prenatal lethality prior to he... 1 | 64
thick ventricular wall 1 | 7
thin ventricular wall 1 | 5
tremors 1 | 34

Disease

osteosarcoma 14 | 7,933
ovarian cancer 13 | 8,484
group 3 medulloblastoma 11 | 2,254
Cancer 10 | 2,346
medulloblastoma, large-cell 10 | 6,234
malignant mesothelioma 9 | 3,162
primitive neuroectodermal tumor 9 | 3,031
psoriasis 9 | 6,685
glioblastoma 8 | 5,572
atypical teratoid / rhabdoid tumor 6 | 4,369
non-small cell lung cancer 6 | 2,798
pediatric high grade glioma 5 | 2,712
invasive ductal carcinoma 4 | 2,950
lung cancer 4 | 4,466
pilocytic astrocytoma 4 | 3,086
Acute lymphoid leukemia 3 | 25
Acute myeloid leukemia, disease 3 | 16
Acute promyelocytic leukemia, FAB M3 3 | 10
Adenocarcinoma of pancreas 3 | 12
Breast cancer 3 | 3,094
Carcinoma 3 | 2,147
Colorectal Neoplasms 3 | 217
Lymphomatous meningitis 3 | 3
Malignant tumor of ovary 3 | 25
Meningeal Leukemia 3 | 7
Metastatic Breast Carcinoma 3 | 21
acute myeloid leukemia 3 | 780
adrenocortical carcinoma 3 | 1,427
diabetes mellitus 3 | 1,663
ependymoma 3 | 2,514
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,956
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,289
posterior fossa group A ependymoma 3 | 1,511
sonic hedgehog group medulloblastoma 3 | 1,482
Chronic progressive external ophthalmoplegia 2 | 18
Familial adenomatous polyposis 2 | 31
Inflammatory dermatosis 2 | 38
Lynch syndrome 2 | 33
Neuropathy 2 | 210
Peripheral Neuropathy 2 | 303
Rheumatoid Arthritis 2 | 1,160
Xeroderma pigmentosum 2 | 41
adult high grade glioma 2 | 2,148
colon cancer 2 | 1,475
gastric cancer 2 | 430
hepatocellular carcinoma 2 | 532
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,988
juvenile dermatomyositis 2 | 1,189
lung adenocarcinoma 2 | 2,713
non primary Sjogren syndrome sicca 2 | 840
oligodendroglioma 2 | 2,849
posterior fossa group B ependymoma 2 | 1,530
progressive supranuclear palsy 2 | 674
subependymal giant cell astrocytoma 2 | 2,287
tuberculosis 2 | 1,557
Adenoma 1 | 165
Age related macular degeneration 1 | 84
Alpers syndrome 1 | 10
Bipolar Disorder 1 | 266
Bladder Neoplasm 1 | 109
Brain disease 1 | 83
Cerebellar Ataxia 1 | 72
Charcot-Marie-Tooth disease 1 | 74
Chronic Lymphocytic Leukemia 1 | 242
Cockayne syndrome 1 | 54
Colorectal Cancer 1 | 47
Deafness 1 | 18
Drug-Induced Liver Injury 1 | 118
Dyskeratosis congenita 1 | 24
Endometrial Neoplasms 1 | 50
Epilepsy 1 | 346
Eye disease 1 | 55
Friedreich ataxia 1 | 23
Gastrointestinal system disease 1 | 50
Heart disease 1 | 279
Hypogonadism 1 | 70
IGA Glomerulonephritis 1 | 454
Influenza 1 | 142
Kidney disease 1 | 396
Lactic acidosis 1 | 42
Leigh disease 1 | 81
Leukodystrophy 1 | 30
Malignant neoplasm of prostate 1 | 67
Menopause present (finding) 1 | 20
Mitochondrial Diseases 1 | 9
Myopia 1 | 99
Neurodegenerative disease 1 | 383
Pain agnosia 1 | 99
Pearson syndrome 1 | 17
Poland syndrome 1 | 7
Ptosis 1 | 42
Seckel syndrome 1 | 34
Seizures 1 | 95
Toxic encephalopathy 1 | 131
Tracheitis 1 | 6
Uterine fibroid 1 | 29
cystic fibrosis and chronic rhinosinusitis 1 | 213
glioblastoma multiforme 1 | 347
medulloblastoma 1 | 1,524
tuberculosis and treatment for 6 months 1 | 686

Tissue

Blood and immune system 27 | 17,995
Digestive Tract 27 | 18,473
Endocrine System 27 | 18,512
Female tissues 27 | 18,647
Liver and Pancreas 27 | 18,136
Male tissues 27 | 17,969
Nervous System 27 | 18,561
Respiratory system 27 | 17,484
Skin and soft tissues 27 | 18,115
Urinary Tract 27 | 18,444
Cardiovascular System 26 | 17,958

Target Family

Enzyme 25 | 4,146
Non-IDG 3 | 11,971

GO Function

DNA-directed DNA polymerase ac... 28 | 28
metal ion binding 1,917 | 1,917
ATP binding 1,467 | 1,467
DNA binding 1,432 | 1,432
zinc ion binding 1,155 | 1,155
poly(A) RNA binding 1,107 | 1,107
transcription factor activity,... 853 | 853
calcium ion binding 695 | 695
G-protein coupled receptor act... 661 | 661
protein homodimerization activ... 569 | 569
RNA binding 445 | 445
olfactory receptor activity 424 | 424
sequence-specific DNA binding 398 | 398
GTP binding 374 | 374
chromatin binding 372 | 372
protein serine/threonine kinas... 336 | 336
RNA polymerase II core promote... 332 | 332
identical protein binding 311 | 311
nucleotide binding 311 | 311
receptor binding 303 | 303
protein kinase binding 289 | 289
enzyme binding 286 | 286
cadherin binding involved in c... 277 | 277
GTPase activator activity 273 | 273
ubiquitin protein ligase bindi... 258 | 258
ubiquitin-protein transferase ... 253 | 253
serine-type endopeptidase acti... 246 | 246
transcription coactivator acti... 241 | 241
transcription factor binding 240 | 240
structural molecule activity 232 | 232
GTPase activity 231 | 231
transcriptional activator acti... 230 | 230
ligase activity 227 | 227
protein heterodimerization act... 227 | 227
structural constituent of ribo... 212 | 212
transcription regulatory regio... 202 | 202
transmembrane signaling recept... 201 | 201
RNA polymerase II regulatory r... 200 | 200
receptor activity 200 | 200
transcription corepressor acti... 198 | 198
magnesium ion binding 197 | 197
signal transducer activity 196 | 196
nucleic acid binding 184 | 184
protein kinase activity 183 | 183
carbohydrate binding 180 | 180
ubiquitin protein ligase activ... 173 | 173
RNA polymerase II transcriptio... 162 | 162
heparin binding 160 | 160
iron ion binding 141 | 141
lipid binding 136 | 136
transporter activity 136 | 136
actin binding 133 | 133
ATPase activity 132 | 132
protein C-terminus binding 129 | 129
heme binding 127 | 127
microtubule binding 123 | 123
protein tyrosine kinase activi... 119 | 119
cytokine activity 118 | 118
Ras guanyl-nucleotide exchange... 113 | 113
mRNA binding 112 | 112
metalloendopeptidase activity 112 | 112
transcriptional repressor acti... 110 | 110
structural constituent of cyto... 108 | 108
Rab GTPase binding 105 | 105
antigen binding 104 | 104
protein domain specific bindin... 102 | 102
peptide antigen binding 101 | 101
guanyl-nucleotide exchange fac... 98 | 98
protein complex binding 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 92 | 92
oxidoreductase activity 91 | 91
transcriptional activator acti... 91 | 91
actin filament binding 89 | 89
hydrolase activity 89 | 89
ion channel binding 89 | 89
protein tyrosine phosphatase a... 88 | 88
electron carrier activity 87 | 87
protease binding 87 | 87
histone binding 86 | 86
integrin binding 83 | 83
growth factor activity 82 | 82
phospholipid binding 82 | 82
single-stranded DNA binding 81 | 81
unfolded protein binding 77 | 77
kinase activity 75 | 75
thiol-dependent ubiquitin-spec... 75 | 75
phosphatidylinositol binding 74 | 74
calmodulin binding 73 | 73
histone deacetylase binding 73 | 73
Rho guanyl-nucleotide exchange... 72 | 72
drug binding 71 | 71
double-stranded DNA binding 70 | 70
peptidase activity 70 | 70
protein N-terminus binding 70 | 70
virus receptor activity 68 | 68
beta-catenin binding 67 | 67
microtubule motor activity 67 | 67
protein transporter activity 67 | 67
calcium channel activity 66 | 66
ubiquitin binding 66 | 66

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Endogenous retrovirus group K member 9 Pol protein ERVK-9 Tdark Non-IDG 0.00000 0
Non-canonical poly(A) RNA polymerase PAPD5 PAPD5 Tdark Enzyme -0.66756 3.45 104
DNA polymerase delta catalytic subunit POLD1 Tclin Enzyme -1.98626 96.6 198
DNA polymerase delta subunit 4 POLD4 Tbio Enzyme -0.78255 7.32 16
DNA polymerase subunit gamma-2, mitochondrial POLG2 Tbio Enzyme -1.31520 20.0 89
DNA polymerase delta subunit 2 POLD2 Tbio Enzyme -0.87787 8.32 110
DNA polymerase iota POLI Tbio Enzyme -3.20393 1616.9 231
DNA polymerase nu POLN Tbio Enzyme -2.08254 127.3 33
DNA polymerase delta subunit 3 POLD3 Tbio Enzyme -1.26358 18.9 134
DNA polymerase theta POLQ Tbio Enzyme -0.47712 2.05 51