Development Level

Tbio 9 | 11,445
Tchem 2 | 1,598

IMPC Phenotype

decreased blood urea nitrogen ... 1 | 51
hemorrhage 1 | 23
preweaning lethality, complete... 1 | 979
preweaning lethality, incomple... 1 | 499

Disease

glioblastoma 6 | 5,792
medulloblastoma, large-cell 6 | 6,241
Cancer 5 | 2,499
Carcinoma 5 | 11,493
atypical teratoid / rhabdoid tumor 5 | 5,112
lung cancer 5 | 4,740
osteosarcoma 5 | 7,950
ovarian cancer 5 | 8,520
psoriasis 4 | 6,694
group 3 medulloblastoma 3 | 4,104
invasive ductal carcinoma 3 | 2,951
lung adenocarcinoma 3 | 2,716
pancreatic cancer 3 | 2,398
Acquired metabolic disease 2 | 336
Breast cancer 2 | 3,578
Insulin Resistance 2 | 72
Melanoma 2 | 711
Metabolic Syndrome 2 | 20
Metabolic syndrome X 2 | 52
Multiple myeloma 2 | 1,332
Pelvic lipomatosis 2 | 3
Type 2 diabetes mellitus 2 | 272
Waldenstrons macroglobulinemia 2 | 765
Xeroderma pigmentosum group G 2 | 16
adult high grade glioma 2 | 3,801
diabetes mellitus 2 | 1,728
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
malignant mesothelioma 2 | 3,232
non-small cell lung cancer 2 | 2,890
pediatric high grade glioma 2 | 1,064
primitive neuroectodermal tumor 2 | 3,035
AOMS1 1 | 4
Adenocarcinoma of lung 1 | 142
Adenoma 1 | 167
Adenomatous Polyposis Coli 1 | 16
Arts syndrome 1 | 26
Bladder Neoplasm 1 | 112
Brain Injuries 1 | 65
Carcinoma, Hepatocellular 1 | 228
Chondroma 1 | 15
Chromosomal Instability 1 | 8
Colonic Neoplasms 1 | 142
Delayed speech and language development 1 | 112
Diabetes Mellitus, Non-Insulin-Dependent 1 | 145
Diabetes Mellitus, Noninsulin-Dependent 1 | 31
Diabetes Mellitus, Type 2 1 | 142
Disease Models, Animal 1 | 155
Disease Progression 1 | 136
Dyslipidemias 1 | 27
Eumycotic mycetoma 1 | 3
FAMILIAL ADENOMATOUS POLYPOSIS 3 1 | 1
Failure to gain weight 1 | 365
Fatty Liver 1 | 70
Glucose Intolerance 1 | 19
Guillain-Barre syndrome 1 | 14
Heart Diseases 1 | 43
Heart disease 1 | 306
Hyperglycemia 1 | 137
Hyperinsulinism 1 | 133
Hyperlipidemia 1 | 43
Hyperpigmentation 1 | 37
Impaired glucose tolerance 1 | 28
Inhalation anthrax 1 | 5
Language Delay 1 | 112
Leiomyoma 1 | 32
Leiomyosarcoma 1 | 24
Leukemia, Lymphocytic, Chronic, B-Cell 1 | 34
Lipodystrophy 1 | 40
Lipoma 1 | 32
Liver carcinoma 1 | 240
Lymphedema 1 | 42
Malignant neoplasm of skin 1 | 15
Meningioma 1 | 41
Mild Mental Retardation 1 | 70
Myocardial Infarction 1 | 151
Neoplasm Invasiveness 1 | 161
Neoplasms 1 | 63
Neurodegenerative disease 1 | 414
Pediatric failure to thrive 1 | 365
Pleomorphic adenoma 1 | 18
Polycystic ovary syndrome 1 | 360
Retinitis pigmentosa Y-linked 1 | 9
Salivary Gland Adenoma, Pleomorphic 1 | 2
Salivary Gland Pleomorphic Adenoma 1 | 2
Seizures 1 | 596
Skin Neoplasms 1 | 69
Somatic mutation 1 | 61
Specific learning disability 1 | 47
Speech Delay 1 | 112
Speech impairment 1 | 112
Stomach Neoplasms 1 | 300
Tremor 1 | 113
Urinary Bladder Neoplasms 1 | 114
Uterine fibroid 1 | 28
Werner syndrome 1 | 29
Xeroderma pigmentosum group D 1 | 33
breast carcinoma 1 | 1,638
cystic fibrosis 1 | 1,696
posterior fossa group B ependymoma 1 | 416
tuberculosis 1 | 2,010

Tissue

Blood and immune system 11 | 16,909
Digestive Tract 11 | 17,369
Endocrine System 11 | 18,159
Female tissues 11 | 17,400
Liver and Pancreas 11 | 16,750
Male tissues 11 | 17,142
Nervous System 11 | 16,725
Respiratory system 11 | 16,393
Skin and soft tissues 11 | 17,230
Urinary Tract 11 | 16,678
Cardiovascular System 10 | 15,192

Target Family

Enzyme 7 | 4,145
Non-IDG 2 | 12,091
Transcription Factor 2 | 1,400

GO Function

DNA-(apurinic or apyrimidinic ... 11 | 11
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Endonuclease III-like protein 1 NTHL1 Tbio Enzyme -1.85066 66.8 155
Nucleic acid dioxygenase ALKBH1 ALKBH1 Tbio Enzyme -2.09946 119.6 149
40S ribosomal protein S3 RPS3 Tbio Non-IDG -2.19489 157.7 218
High mobility group protein HMGI-C HMGA2 Tbio Transcription Factor -3.26377 1794.1 235
Endonuclease 8-like 3 NEIL3 Tbio Enzyme -1.53902 37.4 137
DNA-(apurinic or apyrimidinic site) lyase APEX1 Tchem Enzyme -3.47746 2989.0 646
Aprataxin and PNK-like factor APLF Tbio Non-IDG -1.69718 49.9 226
DNA polymerase beta POLB Tchem Enzyme -2.67364 415.2 298
DNA-(apurinic or apyrimidinic site) lyase 2 APEX2 Tbio Enzyme -1.69087 45.7 137
High mobility group protein HMG-I/HMG-Y HMGA1 Tbio Transcription Factor -2.59141 433.8 253