Development Level

Tbio 3 | 11,445

Disease

Carcinoma 3 | 11,493
Kidney cancer 2 | 2,613
ALPHA-THALASSEMIA/MENTAL RETARDATION SYNDROME, NONDELETION TYPE, X-LINKED 1 | 1
Abnormal hemoglobin finding 1 | 8
Abnormality of fontanelles 1 | 1
Absent frontal sinuses 1 | 8
Acquired flat foot 1 | 72
Alpha thalassemia-X-linked intellectual disability syndrome 1 | 3
Alpha-Thalassemia Myelodysplasia Syndrome 1 | 1
Alpha-thalassemia-myelodysplastic syndrome 1 | 1
Ambiguous Genitalia 1 | 24
Aplasia of frontal sinus 1 | 8
Bloom syndrome 1 | 29
Brachydactyly 1 | 156
Carcinoma of colon 1 | 32
Central incisor gap 1 | 3
Congenital hemivertebra 1 | 25
Congenital hypoplasia of kidney 1 | 32
Coxa valga 1 | 22
Coxa valga deformity 1 | 22
Craniofacial Abnormalities 1 | 151
DOID:2627 1 | 94
Decreased platelet count 1 | 111
Decreased projection of midface 1 | 105
Degenerative brain disorder 1 | 100
Diastema between maxillary central incisors 1 | 3
Drooling 1 | 27
Dysphasia 1 | 23
Dyspnea 1 | 76
Ecchymosis 1 | 66
Everted lower lip vermilion 1 | 54
Exotropia 1 | 35
Fanconi anemia 1 | 56
Fatigue 1 | 182
Flatfoot 1 | 73
Full lower lip 1 | 64
Glioma 1 | 74
Growth Disorders 1 | 35
Hemoglobin H disease 1 | 4
Hyperactive behavior 1 | 91
Hypoplasia of scrotum 1 | 24
Hypoplastic myelodysplasia 1 | 18
Hypotrophic malar bone 1 | 129
Hypotrophic midface 1 | 105
Increased tendency to bruise 1 | 66
Infantile muscular hypotonia 1 | 12
Inverted V-shaped upper lip 1 | 19
Iron-Refractory Iron Deficiency Anemia 1 | 15
Juberg-Marsidi syndrome 1 | 1
Knee joint valgus deformity 1 | 56
Kyphoscoliosis deformity of spine 1 | 60
Lower limb hypertonia 1 | 2
MYELODYSPLASTIC SYNDROME 1 | 53
Malar flattening 1 | 129
Male Pseudohermaphroditism 1 | 19
Malignant lymphoma, non-Hodgkin 1 | 4
Mental Retardation, X-Linked 1 | 23
Mental Retardation-Hypotonic Facies Syndrome, X-Linked, 1 1 | 1
Mental retardation Smith Fineman Myers type 1 | 1
Microcytic hypochromic anemia (disorder) 1 | 10
Midface retrusion 1 | 105
Myelodysplastic Syndromes 1 | 26
Narrow cranium shape 1 | 75
Narrow head shape 1 | 75
Narrow skull shape 1 | 75
Neutrophil count decreased 1 | 47
Nijmegen breakage syndrome 1 | 24
Open mouth 1 | 45
Paroxysmal bursts of laughter 1 | 2
Penile Diseases 1 | 3
Perimembranous ventricular septal defect 1 | 3
Postnatal growth retardation 1 | 57
Progressive mental retardation 1 | 37
Prominent lower lip 1 | 64
Protruding lower lip 1 | 54
Protrusion of tongue 1 | 11
Reduced alpha/beta synthesis ratio 1 | 3
Shawl scrotum 1 | 9
Short upper lip 1 | 7
Sialorrhea 1 | 28
Slender fingers 1 | 5
Small midface 1 | 105
Small testicle 1 | 75
Supratentorial atrophy 1 | 94
Talipes Calcaneovalgus 1 | 6
Tapering fingers (finding) 1 | 25
Tented mouth 1 | 19
Tented upper lip 1 | 19
Thalassemia 1 | 53
Thin upper lip vermilion 1 | 67
Thoracic Diseases 1 | 3
Thrombocytopenia 1 | 197
Triangular nasal tip 1 | 1
Turridolichocephaly 1 | 75
U-Shaped upper lip vermilion 1 | 2
Vesico-Ureteral Reflux 1 | 33
Wide upper central incisors 1 | 3
X- linked recessive 1 | 110
X-linked dominant 1 | 57
Xeroderma pigmentosum 1 | 43

Tissue

Blood and immune system 3 | 16,909
Cardiovascular System 3 | 15,192
Digestive Tract 3 | 17,369
Endocrine System 3 | 18,159
Female tissues 3 | 17,400
Liver and Pancreas 3 | 16,750
Male tissues 3 | 17,142
Nervous System 3 | 16,725
Respiratory system 3 | 16,393
Skin and soft tissues 3 | 17,230
Urinary Tract 3 | 16,678

Target Family

Non-IDG 2 | 12,091
Enzyme 1 | 4,145

GO Function

DNA translocase activity 3 | 3
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
DNA repair and recombination protein RAD54B RAD54B Tbio Non-IDG -1.41173 28.9 153
F-box DNA helicase 1 FBXO18 Tbio Enzyme -1.16507 17.7 87
Transcriptional regulator ATRX ATRX Tbio Non-IDG -2.85277 705.9 248