Development Level

Tbio 1 | 11,445
Tchem 1 | 1,598
Tclin 1 | 613

IMPC Phenotype

abnormal spleen morphology 1 | 55
increased body temperature 1 | 9

Disease

Cancer 2 | 2,499
Carcinoma 2 | 11,493
group 3 medulloblastoma 2 | 4,104
lung cancer 2 | 4,740
Abdominal abscess 1 | 2
Acute Moraxella catarrhalis bronchitis 1 | 1
Acute bacterial bronchitis 1 | 1
Acute bacterial peritonitis 1 | 1
Acute bacterial sinusitis 1 | 1
Acute gonococcal cervicitis 1 | 1
Acute gonococcal urethritis 1 | 1
Acute maxillary sinusitis 1 | 2
Acute monocytic/monoblastic leukemia 1 | 1
Acute osteomyelitis 1 | 1
Acute promyelocytic leukemia, FAB M3 1 | 11
Anthrax 1 | 1
Bacterial Corneal Ulcer Infection 1 | 1
Bacterial conjunctivitis 1 | 10
Bacterial infection due to Klebsiella pneumoniae 1 | 2
Bacterial pneumonia 1 | 4
Bacterial urinary infection 1 | 2
Catecholamines urine increased 1 | 5
Chancroid 1 | 8
Chronic Bacterial Prostatitis 1 | 1
Citrobacter Urinary Tract Infection 1 | 1
Complicated Bacterial Peritonitis 1 | 1
Complicated Bacteroides Peritonitis 1 | 1
Complicated E. Coli Peritonitis 1 | 1
Complicated Klebsiella Peritonitis 1 | 1
Complicated Proteus UTI 1 | 1
Complicated UTI with Pseudomonas Aeruginosa 1 | 1
Cystitis 1 | 15
Diarrhea due to E. Coli 1 | 1
E. Coli Cystitis 1 | 1
E. Coli Pyelonephritis 1 | 1
Enteric campylobacteriosis 1 | 1
Enterobacter Osteomyelitis 1 | 1
Enterobacter Pneumonia 1 | 2
EnterobacterJoint Infection 1 | 1
Enterococcus Complicated UTI 1 | 1
Enterococcus Urinary Tract Infection 1 | 1
Escherichia coli urinary tract infection 1 | 1
Gram-Negative Aerobic Bacillary Pneumonia 1 | 2
Haemophilus Parainfluenzae Pneumonia 1 | 1
Haemophilus influenzae pneumonia 1 | 2
Infection due to Enterobacteriaceae 1 | 1
Infection due to Escherichia coli 1 | 1
Infection due to Pseudomonas aeruginosa 1 | 1
Infection due to Staphylococcus aureus 1 | 1
Infection of skin AND/OR subcutaneous tissue 1 | 2
Infectious diarrheal disease 1 | 1
Infectious disease of abdomen 1 | 2
Infectious disorder of joint 1 | 2
Infective cystitis 1 | 1
Infective otitis externa 1 | 4
Infective otitis media 1 | 3
Invasive Bladder Malignancy 1 | 1
Kaposi's sarcoma associated with AIDS 1 | 1
Klebsiella Nosocomial Pneumonia 1 | 1
Klebsiella cystitis 1 | 1
Lower respiratory tract infection 1 | 14
Malignant otitis externa due to Pseudomonas aeruginosa 1 | 4
Malignant tumor of lung 1 | 5
Malignant tumor of urinary bladder 1 | 5
Moraxella Catarrhalis Chronic Bronchitis 1 | 1
Morganella Morganii Urinary Tract Infection 1 | 1
Neural crest tumor 1 | 7
Nosocomial Pneumonia due to Haemophilus Influenzae 1 | 1
Nosocomial pneumonia 1 | 1
Osteosarcoma of bone 1 | 6
Pneumonia due to Escherichia coli 1 | 2
Pneumonia due to Pseudomonas 1 | 1
Pneumonia due to Streptococcus 1 | 2
Prostatitis 1 | 18
Proteus Prostatitis 1 | 1
Proteus pneumonia 1 | 1
Proteus urinary tract infection 1 | 1
Providencia Urinary Tract Infection 1 | 1
Pseudomonas Aeruginosa Joint Infection 1 | 1
Pseudomonas Aeruginosa Osteomyelitis 1 | 1
Pseudomonas Aeruginosa Urinary Tract Infection 1 | 1
Rhinoscleroma 1 | 5
Septicemia due to Escherichia coli 1 | 1
Serratia Joint Infection 1 | 1
Serratia Osteomyelitis 1 | 1
Serratia Urinary Tract Infection 1 | 1
Shigellosis 1 | 21
Skin and Skin Structure Citrobacter Infection 1 | 1
Skin and Skin Structure Morganella Morganii Infection 1 | 1
Skin and Skin Structure Proteus Infection 1 | 1
Skin and Skin Structure Providencia Infection 1 | 1
Skin and Skin Structure Pseudomonas Aeruginosa Infection 1 | 1
Skin and Skin Structure Serratia Infection 1 | 1
Staphylococcus Aureus Otitis Externa 1 | 4
Staphylococcus Cystitis 1 | 1
Staphylococcus Epidermidis Skin and Skin Structure Infection 1 | 1
Staphylococcus Epidermidis Urinary Tract Infection 1 | 1
Staphylococcus Saprophyticus Urinary Tract Infection 1 | 1
Streptococcus pyogenes infection 1 | 1
Urinary tract infection caused by Klebsiella 1 | 1

Tissue

Endocrine System 3 | 18,159
Blood and immune system 2 | 16,909
Cardiovascular System 2 | 15,192
Digestive Tract 2 | 17,369
Female tissues 2 | 17,400
Liver and Pancreas 2 | 16,750
Male tissues 2 | 17,142
Nervous System 2 | 16,725
Respiratory system 2 | 16,393
Skin and soft tissues 2 | 17,230
Urinary Tract 2 | 16,678

Target Family

Enzyme 2 | 4,145
Non-IDG 1 | 12,091

GO Function

DNA topoisomerase type II (ATP... 3 | 3
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Meiotic recombination protein SPO11 SPO11 Tbio Non-IDG -2.33263 208.9 148
DNA topoisomerase 2-alpha TOP2A Tclin Enzyme -2.88264 723.0 847
DNA topoisomerase 2-beta TOP2B Tchem Enzyme -2.47190 253.5 190