Development Level

Tbio 5 | 11,445

IMPC Phenotype

abnormal vertebrae morphology 1 | 18
decreased body weight 1 | 161
decreased circulating glycerol... 1 | 16
increased circulating triglyce... 1 | 42
increased startle reflex 1 | 112
preweaning lethality, complete... 1 | 979
tremors 1 | 39

Disease

Carcinoma 4 | 11,493
medulloblastoma, large-cell 4 | 6,241
osteosarcoma 4 | 7,950
atypical teratoid / rhabdoid tumor 3 | 5,112
group 3 medulloblastoma 3 | 4,104
ovarian cancer 3 | 8,520
psoriasis 3 | 6,694
Cancer 2 | 2,499
adult high grade glioma 2 | 3,801
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
lung adenocarcinoma 2 | 2,716
lung cancer 2 | 4,740
malignant mesothelioma 2 | 3,232
Abnormality of retinal pigmentation 1 | 111
Abnormality of the retinal vasculature 1 | 59
Acquired immunodeficiency syndrome 1 | 197
Adenocarcinoma of lung 1 | 142
Anteverted nostril 1 | 191
Attention deficit hyperactivity disorder 1 | 278
Attenuation of retinal blood vessels 1 | 16
Atypical scarring of skin 1 | 62
Blind Vision 1 | 111
Blindness, Legal 1 | 110
Breast cancer 1 | 3,578
Broad flat nasal bridge 1 | 236
Cataract 1 | 297
Conductive hearing loss 1 | 123
Congenital anomaly of testis 1 | 52
Congenital hypoplasia of penis 1 | 176
Disease Models, Animal 1 | 155
Dull intelligence 1 | 645
Electroretinogram abnormal 1 | 95
Glaucoma 1 | 239
HIV Infections 1 | 102
Hyperinsulinism 1 | 133
Hypogonadism 1 | 173
Intellectual disability 1 | 1,016
Isolated growth hormone deficiency type II 1 | 4
Keratoconus 1 | 113
Kidney cancer 1 | 2,613
Lens Opacities 1 | 231
Loss of retinal pigment epithelium 1 | 10
Low intelligence 1 | 645
Mental Retardation 1 | 645
Mental deficiency 1 | 645
Myocardial Ischemia 1 | 169
Nasal bridge wide 1 | 236
Neoplasm Metastasis 1 | 168
Night blindness, progressive 1 | 51
Nystagmus 1 | 317
Obesity 1 | 678
Ophthalmoplegia 1 | 106
Optic Atrophy 1 | 242
Photodysphoria 1 | 121
Photophobia 1 | 121
Poor school performance 1 | 645
Retinal pigment epithelial abnormality 1 | 111
Retinitis Pigmentosa 1 | 226
Retinitis pigmentosa 31 1 | 3
Schizophrenia 1 | 1,160
Sensorineural Hearing Loss (disorder) 1 | 284
Spinocerebellar ataxia type 31 1 | 8
Vaccinia 1 | 36
Visual field defects 1 | 19
Waldenstrons macroglobulinemia 1 | 765
acute quadriplegic myopathy 1 | 1,158
adrenocortical carcinoma 1 | 1,428
aldosterone-producing adenoma 1 | 665
breast carcinoma 1 | 1,638
colon cancer 1 | 1,478
dermatomyositis 1 | 966
ductal carcinoma in situ 1 | 1,745
gastric cancer 1 | 459
glioblastoma 1 | 5,792
hepatocellular carcinoma 1 | 547
inflammatory breast cancer 1 | 286
intraductal papillary-mucinous adenoma (IPMA) 1 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 1 | 2,989
invasive ductal carcinoma 1 | 2,951
non-small cell lung cancer 1 | 2,890
posterior fossa group B ependymoma 1 | 416
primitive neuroectodermal tumor 1 | 3,035
relapsing-remitting multiple sclerosis 1 | 18
tuberculosis and treatment for 3 months 1 | 179
ulcerative colitis 1 | 1,819

Tissue

Blood and immune system 5 | 16,909
Cardiovascular System 5 | 15,192
Digestive Tract 5 | 17,369
Endocrine System 5 | 18,159
Female tissues 5 | 17,400
Liver and Pancreas 5 | 16,750
Male tissues 5 | 17,142
Nervous System 5 | 16,725
Respiratory system 5 | 16,393
Skin and soft tissues 5 | 17,230
Urinary Tract 5 | 16,678

Target Family

Non-IDG 3 | 12,091
Enzyme 1 | 4,145
Epigenetic 1 | 242

GO Function

DNA topoisomerase binding 5 | 5
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Serine/arginine-rich splicing factor 1 SRSF1 Tbio Non-IDG -2.91064 772.6 223
Condensin complex subunit 2 NCAPH Tbio Non-IDG -1.54249 35.6 257
E3 ubiquitin-protein ligase Topors TOPORS Tbio Enzyme -1.94964 92.8 174
Histone-lysine N-methyltransferase SETMAR SETMAR Tbio Epigenetic -1.33346 26.5 119
Nucleolin NCL Tbio Non-IDG -2.84337 683.3 487