Development Level

Tbio 9 | 11,445
Tchem 1 | 1,598

IMPC Phenotype

decreased blood urea nitrogen ... 1 | 51
increased circulating alkaline... 1 | 122

Disease

osteosarcoma 7 | 7,950
Carcinoma 5 | 11,493
group 3 medulloblastoma 5 | 4,104
Cancer 4 | 2,499
glioblastoma 4 | 5,792
lung cancer 4 | 4,740
primitive neuroectodermal tumor 4 | 3,035
psoriasis 4 | 6,694
atypical teratoid / rhabdoid tumor 3 | 5,112
malignant mesothelioma 3 | 3,232
medulloblastoma, large-cell 3 | 6,241
ovarian cancer 3 | 8,520
tuberculosis 3 | 2,010
Adenoma 2 | 167
Adenomatous Polyposis Coli 2 | 16
Autosomal recessive predisposition 2 | 1,442
Breast cancer 2 | 3,578
Cockayne syndrome 2 | 60
Colorectal adenoma 2 | 15
Lynch syndrome 2 | 35
Multiple myeloma 2 | 1,332
Pick disease 2 | 1,894
Waldenstrons macroglobulinemia 2 | 765
Xeroderma pigmentosum group G 2 | 16
astrocytic glioma 2 | 2,597
breast carcinoma 2 | 1,638
dermatomyositis 2 | 966
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
invasive ductal carcinoma 2 | 2,951
oligodendroglioma 2 | 2,850
Acquired immunodeficiency syndrome 1 | 197
Adenocarcinoma 1 | 122
Adenocarcinoma of lung 1 | 142
Adenocarcinoma of lung (disorder) 1 | 60
Aphasia 1 | 26
Autistic Disorder 1 | 364
Brain Diseases 1 | 24
Carcinoma of colon 1 | 32
Carcinoma, Renal Cell 1 | 124
Cerebrovascular disease 1 | 238
Colonic Neoplasms 1 | 142
Dementia 1 | 175
Dermatologic disorders 1 | 93
Diarrhea 1 | 253
Encephalitis 1 | 64
Endometrial cancer 1 | 311
Familial adenomatous polyposis 1 | 32
Fatty Liver 1 | 70
Fibrous dysplasia 1 | 15
Frontotemporal dementia 1 | 51
Gastric Cancer, Hereditary Diffuse 1 | 12
Gastrointestinal system disease 1 | 54
Glucose Intolerance 1 | 19
Hearing Loss, Noise-Induced 1 | 5
Heart Diseases 1 | 43
Heart disease 1 | 306
Hemangioma 1 | 69
Huntington Disease 1 | 13
Hyperinsulinism 1 | 133
Hyperlipidemia 1 | 43
Impaired glucose tolerance 1 | 28
Insulin Resistance 1 | 72
Intracranial hypotension 1 | 10
Isolated cases 1 | 72
Juvenile polyposis syndrome 1 | 7
Leiomyoma 1 | 32
Lung Neoplasms 1 | 232
Lung disease 1 | 142
Lymphatic system disease 1 | 15
Lymphoma 1 | 81
Lymphoproliferative syndrome 1 | 58
Malaria 1 | 160
Malignant neoplasm of skin 1 | 15
Measles 1 | 22
Meningioma 1 | 41
Metabolic syndrome X 1 | 52
Motor Skills Disorders 1 | 8
Multiple system atrophy 1 | 29
Neoplasm of stomach 1 | 11
Nerve Degeneration 1 | 121
Neurilemmoma 1 | 23
Noise-induced hearing loss 1 | 5
Osteomyelitis 1 | 42
Pancreatitis 1 | 123
Papilledema 1 | 11
Parkinson's disease 1 | 392
Peutz-Jeghers syndrome 1 | 21
Pilomatrixoma 1 | 12
Prenatal Exposure Delayed Effects 1 | 11
Renal Cell Carcinoma 1 | 214
Renal Cell Carcinoma, Nonpapillary 1 | 7
Skin Diseases 1 | 71
Skin Neoplasms 1 | 69
Somatic mutation 1 | 61
Stomach Carcinoma 1 | 11
Stomach Neoplasms 1 | 300
Urologic Neoplasms 1 | 8
Xeroderma pigmentosum group D 1 | 33
atypical teratoid/rhabdoid tumor 1 | 357
sarcoidosis 1 | 370

Tissue

Blood and immune system 10 | 16,909
Digestive Tract 10 | 17,369
Endocrine System 10 | 18,159
Female tissues 10 | 17,400
Liver and Pancreas 10 | 16,750
Male tissues 10 | 17,142
Nervous System 10 | 16,725
Respiratory system 10 | 16,393
Skin and soft tissues 10 | 17,230
Urinary Tract 10 | 16,678
Cardiovascular System 9 | 15,192

Target Family

Enzyme 9 | 4,145
Transcription Factor 1 | 1,400

GO Function

DNA N-glycosylase activity 10 | 10
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Endonuclease III-like protein 1 NTHL1 Tbio Enzyme -1.85066 66.8 155
Adenine DNA glycosylase MUTYH Tbio Enzyme -2.86910 750.8 255
G/T mismatch-specific thymine DNA glycosylase TDG Tbio Enzyme -2.46252 297.6 225
Single-strand selective monofunctional uracil DNA glycosylase SMUG1 Tbio Enzyme -4.31831 20587.4 199
N-glycosylase/DNA lyase OGG1 Tbio Enzyme -3.26147 1834.9 293
Methyl-CpG-binding domain protein 4 MBD4 Tbio Transcription Factor -1.99625 98.6 183
Endonuclease 8-like 2 NEIL2 Tbio Enzyme -1.74921 49.0 107
Endonuclease 8-like 3 NEIL3 Tbio Enzyme -1.53902 37.4 137
DNA-3-methyladenine glycosylase MPG Tchem Enzyme -2.84708 687.5 316
Endonuclease 8-like 1 NEIL1 Tbio Enzyme -2.01238 106.1 202