Development Level

Tbio 11 | 11,445
Tchem 4 | 1,598

IMPC Phenotype

preweaning lethality, complete... 4 | 979
embryonic lethality prior to t... 2 | 278
abnormal behavior 1 | 298
abnormal embryo size 1 | 220
abnormal epididymis morphology 1 | 42
abnormal heart morphology 1 | 162
abnormal iris morphology 1 | 13
abnormal optic disc morphology 1 | 10
abnormal ovary morphology 1 | 7
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
absent epididymis 1 | 3
corneal opacity 1 | 32
decreased blood urea nitrogen ... 1 | 51
decreased circulating serum al... 1 | 82
decreased lymphocyte cell numb... 1 | 83
decreased prepulse inhibition 1 | 82
embryonic growth retardation 1 | 106
enlarged heart 1 | 210
hemorrhage 1 | 23
hypoactivity 1 | 132
impaired pupillary reflex 1 | 26
increased lean body mass 1 | 172
increased mean platelet volume 1 | 45
increased monocyte cell number 1 | 63
increased neutrophil cell numb... 1 | 46
increased or absent threshold ... 1 | 101
irregularly shaped pupil 1 | 7
persistence of hyaloid vascula... 1 | 33

Disease

Carcinoma 12 | 11,493
ovarian cancer 10 | 8,520
lung cancer 9 | 4,740
Cancer 8 | 2,499
osteosarcoma 8 | 7,950
medulloblastoma, large-cell 7 | 6,241
malignant mesothelioma 6 | 3,232
psoriasis 6 | 6,694
atypical teratoid / rhabdoid tumor 5 | 5,112
primitive neuroectodermal tumor 5 | 3,035
Leukemia, Myelocytic, Acute 4 | 120
Pick disease 4 | 1,894
ependymoma 4 | 4,679
glioblastoma 4 | 5,792
group 3 medulloblastoma 4 | 4,104
group 4 medulloblastoma 4 | 1,855
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
juvenile dermatomyositis 4 | 1,187
non-small cell lung cancer 4 | 2,890
oligodendroglioma 4 | 2,850
Alzheimer's disease 3 | 658
Breast cancer 3 | 3,578
Intellectual disability 3 | 1,016
Leukemia, Myeloid, Acute 3 | 105
Short stature 3 | 531
adult high grade glioma 3 | 3,801
interstitial cystitis 3 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
invasive ductal carcinoma 3 | 2,951
lung adenocarcinoma 3 | 2,716
ulcerative colitis 3 | 1,819
Anemia 2 | 365
Astrocytoma, Pilocytic 2 | 3,081
Breast Neoplasms 2 | 445
Colonic Neoplasms 2 | 142
Duchenne muscular dystrophy 2 | 601
Dull intelligence 2 | 645
Hematologic cancer 2 | 12
Immune system cancer 2 | 140
Immunologic Deficiency Syndromes 2 | 113
Kleefstra syndrome 2 | 12
Low intelligence 2 | 645
Lung Neoplasms 2 | 232
Lymphedema 2 | 42
Mental Retardation 2 | 645
Mental deficiency 2 | 645
Neoplasm Invasiveness 2 | 161
Neoplasm Metastasis 2 | 168
Neutrophil count decreased 2 | 47
Poor school performance 2 | 645
Rheumatoid arthritis 2 | 1,191
Somatic mutation 2 | 61
astrocytic glioma 2 | 2,597
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 510
breast carcinoma 2 | 1,638
cutaneous lupus erythematosus 2 | 1,057
cystic fibrosis 2 | 1,696
ductal carcinoma in situ 2 | 1,745
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
pancreatic cancer 2 | 2,398
pituitary cancer 2 | 1,972
posterior fossa group A ependymoma 2 | 468
primary Sjogren syndrome 2 | 735
primary pancreatic ductal adenocarcinoma 2 | 1,109
tuberculosis 2 | 2,010
tuberculosis and treatment for 6 months 2 | 409
12q14 microdeletion syndrome 1 | 2
Abnormal platelet function 1 | 12
Abnormality of the urinary system 1 | 21
Anemia, Diamond-Blackfan 1 | 16
Anemia, Macrocytic 1 | 18
Aniridia 1 | 25
Autosomal recessive nonsyndromic deafness 33 1 | 4
Autosomal recessive nonsyndromic deafness 79 1 | 3
Birth Weight 1 | 13
Chancroid 1 | 8
Congenital thrombocytopenia 1 | 3
Diamond-Blackfan anemia 1 | 31
Diaphragmatic Hernia 1 | 40
Excess nuchal skin 1 | 30
Hand deformities 1 | 32
Hernia, Diaphragmatic 1 | 40
Hypoplastic iliac wing 1 | 19
Monocytopenia 1 | 2
Moyamoya disease 1 | 10
Multiple, subcutaneous nodules 1 | 53
Osteopoikilosis 1 | 6
Osteopoikilosis (disorder) 1 | 2
Pelvic lipomatosis 1 | 3
Petechiae 1 | 13
Recurrent fungal infections 1 | 13
Recurrent viral infections 1 | 15
Reticulocytosis 1 | 20
Short middle phalanx of the 5th finger 1 | 13
Spade-like hand 1 | 16
Speckled iris 1 | 4
Subcutaneous nodule 1 | 53
WAGR syndrome 1 | 10
genital abnormal 1 | 17
reproductive system abnormality 1 | 17

Tissue

Blood and immune system 15 | 16,909
Digestive Tract 15 | 17,369
Endocrine System 15 | 18,159
Female tissues 15 | 17,400
Liver and Pancreas 15 | 16,750
Male tissues 15 | 17,142
Nervous System 15 | 16,725
Respiratory system 15 | 16,393
Skin and soft tissues 15 | 17,230
Urinary Tract 15 | 16,678
Cardiovascular System 14 | 15,192

Target Family

Transcription Factor 10 | 1,400
Non-IDG 3 | 12,091
Epigenetic 2 | 242

GO Function

C2H2 zinc finger domain bindin... 15 | 15
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Zinc finger protein ZXDC ZXDC Tbio Transcription Factor -0.49831 4.10 62
High mobility group protein HMGI-C HMGA2 Tbio Transcription Factor -3.26377 1794.1 235
Zinc finger X-linked protein ZXDA ZXDA Tbio Transcription Factor -0.64098 3.30 31
Methyl-CpG-binding domain protein 2 MBD2 Tchem Transcription Factor -1.74971 47.7 297
Transcription initiation factor TFIID subunit 9 TAF9 Tbio Non-IDG -2.18859 223.1 83
Histone-lysine N-methyltransferase EHMT2 EHMT2 Tchem Epigenetic -2.49970 327.4 277
Wilms tumor protein WT1 Tbio Transcription Factor -3.48344 3138.9 571
Transcription factor COE1 EBF1 Tbio Transcription Factor -2.78602 600.3 129
Splicing factor U2AF 65 kDa subunit U2AF2 Tbio Non-IDG -2.14043 127.8 183
THAP domain-containing protein 7 THAP7 Tbio Transcription Factor -0.07311 1.18 19