Development Level

Tbio 4 | 11,445
Tchem 4 | 1,598
Tclin 3 | 613

IMPC Phenotype

decreased circulating glucose ... 1 | 126
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular vol... 1 | 79
decreased mean platelet volume 1 | 25
decreased prepulse inhibition 1 | 82
impaired glucose tolerance 1 | 75
increased circulating bilirubi... 1 | 16
increased kidney weight 1 | 6
limb grasping 1 | 41

Disease

Carcinoma 11 | 11,493
Kidney cancer 10 | 2,613
Colorectal Neoplasms 8 | 243
lung cancer 7 | 4,740
ovarian cancer 7 | 8,520
atypical teratoid / rhabdoid tumor 6 | 5,112
lung carcinoma 6 | 2,843
osteosarcoma 6 | 7,950
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,962
Cancer 5 | 2,499
adult high grade glioma 5 | 3,801
ependymoma 5 | 4,679
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
malignant mesothelioma 5 | 3,232
Arthritis, Rheumatoid 4 | 174
Autosomal recessive predisposition 4 | 1,442
Dubin-Johnson syndrome 4 | 6
Liver cancer 4 | 604
Rheumatoid arthritis 4 | 1,191
Skin cancer 4 | 469
glioblastoma 4 | 5,792
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
medulloblastoma, large-cell 4 | 6,241
non-small cell lung cancer 4 | 2,890
psoriasis 4 | 6,694
Adverse reaction to drug 3 | 61
Bilirubin metabolic disorder 3 | 41
Cholestasis 3 | 155
Diarrhea 3 | 253
Disease Progression 3 | 136
Drug-Related Side Effects and Adverse Reactions 3 | 62
Endometriosis 3 | 540
Liver disease 3 | 237
Melanoma 3 | 711
Pick disease 3 | 1,894
Pseudoxanthoma elasticum 3 | 18
cystic fibrosis 3 | 1,696
interstitial cystitis 3 | 2,312
invasive ductal carcinoma 3 | 2,951
lung adenocarcinoma 3 | 2,716
non primary Sjogren syndrome sicca 3 | 891
subependymal giant cell astrocytoma 3 | 2,287
Alopecia 2 | 115
Anteverted nostril 2 | 191
Astrocytoma, Pilocytic 2 | 3,081
Biliary cirrhosis 2 | 45
Breast cancer 2 | 3,578
Carcinoma, squamous cell of head and neck 2 | 31
Chemical and Drug Induced Liver Injury 2 | 195
Epilepsy 2 | 792
Failure to gain weight 2 | 365
Heart Diseases 2 | 43
Hepatomegaly 2 | 285
Hypertrichotic osteochondrodysplasia Cantu type 2 | 5
Large for gestational age 2 | 11
Liver Cirrhosis, Experimental 2 | 769
Long philtrum 2 | 137
Pediatric failure to thrive 2 | 365
Peripheral Neuropathy 2 | 134
Primary biliary cirrhosis 2 | 51
Retinal Diseases 2 | 55
Seizures 2 | 596
Squamous cell carcinoma of the head and neck 2 | 29
Substance-Related Disorders 2 | 115
active Crohn's disease 2 | 922
active ulcerative colitis 2 | 764
ductal carcinoma in situ 2 | 1,745
esophageal adenocarcinoma 2 | 737
group 4 medulloblastoma 2 | 1,855
non-small cell lung carcinoma 2 | 317
pancreatic cancer 2 | 2,398
primary Sjogren syndrome 2 | 735
primitive neuroectodermal tumor 2 | 3,035
tuberculosis 2 | 2,010
Abnormality of the gastric mucosa 1 | 2
Broad ribs 1 | 12
Bullet vertebral body 1 | 17
Chronic lung disease 1 | 6
Diabetes Mellitus, Transient Neonatal, 1 1 | 4
Diffusely thickened skin 1 | 20
Distal intestinal obstruction syndrome 1 | 2
Hyperplasia of supraorbital margins 1 | 19
Hyperplasia of supraorbital ridge 1 | 19
Hypertrophy of supraorbital margins 1 | 19
Hypertrophy of supraorbital ridge 1 | 19
Idiopathic bronchiectasis 1 | 4
Limb contractures 1 | 6
Low anterior hairline 1 | 30
Meconium ileus 1 | 3
Meconium ileus on ultrasonography 1 | 2
Metaphyseal widening 1 | 22
Mouth Abnormalities 1 | 14
Ovoid vertebral bodies 1 | 17
Pachyderma 1 | 20
Pericardial effusion 1 | 14
Prominent supraorbital ridges 1 | 19
Recurrent bronchopulmonary infections 1 | 2
Restrictive cardiomyopathy 1 | 11
permanent neonatal diabetes mellitus 1 | 9

Tissue

Blood and immune system 11 | 16,909
Digestive Tract 11 | 17,369
Endocrine System 11 | 18,159
Female tissues 11 | 17,400
Liver and Pancreas 11 | 16,750
Male tissues 11 | 17,142
Nervous System 11 | 16,725
Respiratory system 11 | 16,393
Skin and soft tissues 11 | 17,230
Urinary Tract 11 | 16,678
Cardiovascular System 8 | 15,192

Target Family

Transporter 10 | 473
Ion Channel 1 | 344

GO Function

ATPase-coupled anion transmemb... 11 | 11
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Canalicular multispecific organic anion transporter 2 ABCC3 Tbio Transporter -2.46032 287.4 214
Multidrug resistance-associated protein 4 ABCC4 Tchem Transporter -2.56001 341.6 352
Multidrug resistance-associated protein 5 ABCC5 Tchem Transporter -2.10085 119.3 262
ATP-binding cassette sub-family C member 8 ABCC8 Tclin Transporter -2.92120 869.9 193
ATP-binding cassette sub-family C member 11 ABCC11 Tbio Transporter -1.75609 58.9 249
Multidrug resistance-associated protein 1 ABCC1 Tchem Transporter -2.81072 662.2 328
Multidrug resistance-associated protein 6 ABCC6 Tbio Transporter -2.71911 547.1 100
Canalicular multispecific organic anion transporter 1 ABCC2 Tchem Transporter -2.90204 834.9 234
Multidrug resistance-associated protein 7 ABCC10 Tbio Transporter -1.53768 35.8 221
Cystic fibrosis transmembrane conductance regulator CFTR Tclin Ion Channel -3.79415 6397.4 472