Development Level

Tbio 25 | 11,445
Tchem 6 | 1,598
Tclin 5 | 613
Tdark 4 | 6,588

IMPC Phenotype

preweaning lethality, complete... 3 | 979
abnormal behavior 2 | 298
decreased caudal vertebrae num... 2 | 53
decreased circulating glucose ... 2 | 126
decreased mean platelet volume 2 | 25
increased heart rate variabili... 2 | 7
abnormal behavioral response t... 1 | 66
abnormal embryo size 1 | 220
abnormal lens morphology 1 | 81
abnormal male genitalia morpho... 1 | 3
abnormal response to new envir... 1 | 10
abnormal response to tactile s... 1 | 17
abnormal sleep behavior 1 | 70
brachydactyly 1 | 19
cardiovascular system phenotyp... 1 | 36
cataract 1 | 92
decreased body weight 1 | 161
decreased circulating calcium ... 1 | 36
decreased circulating choleste... 1 | 93
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased grip strength 1 | 116
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular vol... 1 | 79
decreased prepulse inhibition 1 | 82
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
hypoactivity 1 | 132
impaired glucose tolerance 1 | 75
increased body weight 1 | 25
increased circulating HDL chol... 1 | 80
increased circulating bilirubi... 1 | 16
increased fasted circulating g... 1 | 76
increased hematocrit 1 | 46
increased kidney weight 1 | 6
increased mean corpuscular hem... 1 | 96
increased prepulse inhibition 1 | 32
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
limb grasping 1 | 41
syndactyly 1 | 23
thrombocytosis 1 | 27
vertebral fusion 1 | 23

Disease

Carcinoma 37 | 11,493
Kidney cancer 27 | 2,613
Colorectal Neoplasms 26 | 243
osteosarcoma 19 | 7,950
ovarian cancer 19 | 8,520
psoriasis 18 | 6,694
Breast cancer 16 | 3,578
lung cancer 16 | 4,740
lung carcinoma 15 | 2,843
glioblastoma 14 | 5,792
malignant mesothelioma 14 | 3,232
pancreatic ductal adenocarcinoma liver metastasis 14 | 1,962
atypical teratoid / rhabdoid tumor 13 | 5,112
medulloblastoma, large-cell 13 | 6,241
Autosomal recessive predisposition 11 | 1,442
ependymoma 11 | 4,679
intraductal papillary-mucinous adenoma (IPMA) 11 | 2,955
invasive ductal carcinoma 11 | 2,951
lung adenocarcinoma 11 | 2,716
intraductal papillary-mucinous neoplasm (IPMN) 10 | 3,291
non-small cell lung cancer 10 | 2,890
Cancer 9 | 2,499
ductal carcinoma in situ 9 | 1,745
intraductal papillary-mucinous carcinoma (IPMC) 9 | 2,989
Disease Progression 8 | 136
Skin cancer 8 | 469
adult high grade glioma 8 | 3,801
oligodendroglioma 8 | 2,850
Astrocytoma, Pilocytic 7 | 3,081
Liver cancer 7 | 604
Pick disease 7 | 1,894
Rheumatoid arthritis 7 | 1,191
colon cancer 7 | 1,478
Adverse reaction to drug 6 | 61
Arthritis, Rheumatoid 6 | 174
Cholestasis 6 | 155
Drug-Related Side Effects and Adverse Reactions 6 | 62
Liver Cirrhosis, Experimental 6 | 769
Melanoma 6 | 711
active ulcerative colitis 6 | 764
adrenocortical carcinoma 6 | 1,428
astrocytic glioma 6 | 2,597
non-small cell lung carcinoma 6 | 317
pancreatic cancer 6 | 2,398
tuberculosis 6 | 2,010
ulcerative colitis 6 | 1,819
Alzheimer's disease 5 | 658
Atopic dermatitis 5 | 952
Dubin-Johnson syndrome 5 | 6
Epilepsy 5 | 792
Hepatomegaly 5 | 285
Peripheral Neuropathy 5 | 134
Tangier disease 5 | 10
active Crohn's disease 5 | 922
breast carcinoma 5 | 1,638
group 3 medulloblastoma 5 | 4,104
group 4 medulloblastoma 5 | 1,855
interstitial cystitis 5 | 2,312
primitive neuroectodermal tumor 5 | 3,035
progressive supranuclear palsy 5 | 676
subependymal giant cell astrocytoma 5 | 2,287
Adrenoleukodystrophy 4 | 29
Biliary cirrhosis 4 | 45
Carcinoma, squamous cell of head and neck 4 | 31
Chemical and Drug Induced Liver Injury 4 | 195
Diarrhea 4 | 253
Endometrial cancer 4 | 311
Failure to gain weight 4 | 365
Liver disease 4 | 237
Pediatric failure to thrive 4 | 365
Pseudoxanthoma elasticum 4 | 18
Schizophrenia 4 | 1,160
Squamous cell carcinoma of the head and neck 4 | 29
acute quadriplegic myopathy 4 | 1,158
aldosterone-producing adenoma 4 | 665
cutaneous lupus erythematosus 4 | 1,057
cystic fibrosis 4 | 1,696
dermatomyositis 4 | 966
facioscapulohumeral dystrophy 4 | 288
pediatric high grade glioma 4 | 1,064
Anemia 3 | 365
Anteverted nostril 3 | 191
Atherosclerosis 3 | 291
Bipolar Disorder 3 | 666
Cardiovascular system disease 3 | 246
Coronary artery disease 3 | 268
Down syndrome 3 | 499
Endometriosis 3 | 540
Lipid metabolism disorder 3 | 114
Low Vision 3 | 174
Prostatic Neoplasms 3 | 495
Psychotic Disorders 3 | 151
Seizures 3 | 596
Visual Impairment 3 | 174
Waldenstrons macroglobulinemia 3 | 765
fibroadenoma 3 | 559
non diabetic and post-ischemic heart failure 3 | 200
posterior fossa group A ependymoma 3 | 468
primary Sjogren syndrome 3 | 735
primary pancreatic ductal adenocarcinoma 3 | 1,109

Tissue

Endocrine System 38 | 18,159
Female tissues 38 | 17,400
Nervous System 38 | 16,725
Digestive Tract 37 | 17,369
Skin and soft tissues 37 | 17,230
Liver and Pancreas 36 | 16,750
Male tissues 36 | 17,142
Urinary Tract 36 | 16,678
Blood and immune system 35 | 16,909
Respiratory system 34 | 16,393
Cardiovascular System 29 | 15,192

Target Family

Transporter 38 | 473
Enzyme 1 | 4,145
Ion Channel 1 | 344

GO Function

ATPase activity, coupled to tr... 40 | 40
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
ATP-binding cassette sub-family A member 10 ABCA10 Tdark Transporter -0.25772 2.27 36
ATP-binding cassette sub-family A member 5 ABCA5 Tbio Transporter -1.09683 13.2 131
ATP-binding cassette sub-family D member 3 ABCD3 Tbio Transporter -1.82051 64.2 166
ATP-binding cassette sub-family A member 3 ABCA3 Tbio Transporter -2.25972 187.7 32
ATP-binding cassette sub-family B member 8, mitochondrial ABCB8 Tbio Transporter -0.85002 7.18 96
ATP-binding cassette sub-family A member 13 ABCA13 Tbio Transporter -1.12588 13.9 0
ATP-binding cassette sub-family A member 12 ABCA12 Tbio Transporter -2.05873 115.5 66
Putative ATP-binding cassette sub-family A member 11 ABCA11P Tdark Transporter 0.00000 0
ATP-binding cassette sub-family A member 8 ABCA8 Tbio Transporter -0.83170 7.18 88
Canalicular multispecific organic anion transporter 2 ABCC3 Tbio Transporter -2.46032 287.4 214