Development Level

Tbio 3 | 11,445

Disease

Autosomal recessive predisposition 2 | 1,442
Cortical gyral simplification 2 | 19
Dilated ventricles (finding) 2 | 121
Hypoplasia of corpus callosum 2 | 90
Neurodegenerative disease 2 | 414
Progressive microcephaly 2 | 32
osteosarcoma 2 | 7,950
ATAXIA-OCULOMOTOR APRAXIA 4 1 | 1
Absent reflex 1 | 92
Absent speech 1 | 43
Absent tendon reflex 1 | 92
Anus disease 1 | 3
Apraxia 1 | 26
Astrocytoma, Pilocytic 1 | 3,081
Ataxia with oculomotor apraxia type 1 1 | 5
Atrophy of cerebellum 1 | 103
Bowed and upward slanting eyebrows 1 | 41
Broad flat nasal bridge 1 | 236
Byzanthine arch palate 1 | 194
Cerebellar Ataxia 1 | 304
Cerebellar degeneration 1 | 103
Cerebral atrophy 1 | 178
Cognitive delay 1 | 608
DNA Repair-Deficiency Disorders 1 | 1
Defective or absent horizontal voluntary eye movements 1 | 25
Delayed myelination 1 | 22
Developmental Disabilities 1 | 23
Dystonia 1 | 164
Dystonic disease 1 | 106
Early infantile epileptic encephalopathy with suppression bursts 1 | 10
Encephalopathies 1 | 43
Epilepsy 1 | 792
Epileptic encephalopathy 1 | 26
Esotropia 1 | 31
Exophthalmos 1 | 112
Global developmental delay 1 | 608
Growth delay 1 | 114
Growth failure 1 | 114
Growth retardation 1 | 115
Hyperactive behavior 1 | 91
Hyperreflexia 1 | 209
Infratentorial atrophy 1 | 103
Liver Cirrhosis, Experimental 1 | 769
Long eyelashes 1 | 37
Long palpebral fissure 1 | 17
MICROCEPHALY, SEIZURES, AND DEVELOPMENTAL DELAY 1 | 1
Mental and motor retardation 1 | 608
Microcephaly 1 | 166
Motor delay 1 | 147
Muscle Spasticity 1 | 195
Muscle hypotonia 1 | 571
Nasal bridge wide 1 | 236
Neurogenic Muscular Atrophy 1 | 139
Neurogenic muscle atrophy, especially in the lower limbs 1 | 139
Neuropathy 1 | 261
No development of motor milestones 1 | 147
Nystagmus 1 | 317
Oculomotor apraxia 1 | 25
PONTOCEREBELLAR HYPOPLASIA, TYPE 10 1 | 1
Peripheral Neuropathy 1 | 134
Pick disease 1 | 1,894
Pontocerebellar hypoplasia 1 | 36
Poor eye contact 1 | 12
Poor growth 1 | 114
Prenatal onset 1 | 139
Prominent eyes 1 | 96
Prominent globes 1 | 96
Protruding eyes 1 | 96
Quadriplegia 1 | 20
Rapidly progressive 1 | 27
Rapidly progressive disorder 1 | 27
Reflex, Deep Tendon, Absent 1 | 92
Rheumatoid arthritis 1 | 1,191
Seizures 1 | 596
Severe mental retardation (I.Q. 20-34) 1 | 99
Short nose 1 | 132
Skeletal muscle atrophy 1 | 139
Small head 1 | 374
Small nose 1 | 132
Thick, flared eyebrows 1 | 41
Thin hypoplastic alae nasi 1 | 51
Thin upper lip vermilion 1 | 67
Very poor growth 1 | 114
X-linked cerebral adrenoleukodystrophy 1 | 116
active Crohn's disease 1 | 922
adult high grade glioma 1 | 3,801
astrocytic glioma 1 | 2,597
glioblastoma 1 | 5,792
group 3 medulloblastoma 1 | 4,104
lung cancer 1 | 4,740
muscle degeneration 1 | 139
nonverbal 1 | 43
oligodendroglioma 1 | 2,850
ovarian cancer 1 | 8,520
pontocerebellar hypoplasia type 10 1 | 1
primitive neuroectodermal tumor 1 | 3,035
psoriasis 1 | 6,694
sarcoidosis 1 | 370
tuberculosis 1 | 2,010
tuberculosis and treatment for 6 months 1 | 409

Tissue

Blood and immune system 3 | 16,909
Cardiovascular System 3 | 15,192
Digestive Tract 3 | 17,369
Endocrine System 3 | 18,159
Female tissues 3 | 17,400
Liver and Pancreas 3 | 16,750
Male tissues 3 | 17,142
Nervous System 3 | 16,725
Respiratory system 3 | 16,393
Skin and soft tissues 3 | 17,230
Urinary Tract 3 | 16,678

Target Family

Enzyme 2 | 4,145
Non-IDG 1 | 12,091

GO Function

ATP-dependent polydeoxyribonuc... 3 | 3
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
NEDD4-binding protein 2 N4BP2 Tbio Non-IDG -0.54327 3.39 19
Bifunctional polynucleotide phosphatase/kinase PNKP Tbio Enzyme -1.79273 59.8 231
Polyribonucleotide 5'-hydroxyl-kinase Clp1 CLP1 Tbio Enzyme -1.48371 28.0 159