Development Level

Tbio 3 | 11,651
Tchem 1 | 1,388

IMPC Phenotype

embryonic lethality prior to o... 2 | 239
embryonic lethality prior to t... 2 | 278
preweaning lethality, complete... 2 | 979
enlarged heart 1 | 210

Disease

Carcinoma 4 | 11,493
lung cancer 4 | 4,740
Kidney cancer 3 | 2,613
medulloblastoma, large-cell 3 | 6,241
osteosarcoma 3 | 7,950
ovarian cancer 3 | 8,520
Autosomal recessive predisposition 2 | 1,442
Chromosome Breakage 2 | 36
Dull intelligence 2 | 645
Fanconi anemia 2 | 56
Fetal Growth Retardation 2 | 189
Infant, Small for Gestational Age 2 | 176
Intellectual disability 2 | 1,016
Intrauterine retardation 2 | 176
Low intelligence 2 | 645
Mental Retardation 2 | 645
Mental deficiency 2 | 645
Poor school performance 2 | 645
Rothmund-Thomson syndrome 2 | 19
Small head 2 | 374
adult high grade glioma 2 | 3,801
colon cancer 2 | 1,478
glioblastoma 2 | 5,792
group 3 medulloblastoma 2 | 4,104
malignant mesothelioma 2 | 3,232
primitive neuroectodermal tumor 2 | 3,035
psoriasis 2 | 6,694
Abnormality of retinal pigmentation 1 | 111
Abnormality of the retinal vasculature 1 | 59
Atypical scarring of skin 1 | 62
Azoospermia 1 | 110
Baller-Gerold syndrome 1 | 12
Birthmark 1 | 35
Blind Vision 1 | 111
Blindness, Legal 1 | 110
Bronchiectasis 1 | 64
Cafe-au-Lait Spots 1 | 37
Capuchin ears 1 | 17
Coloboma of optic disc 1 | 9
Conductive hearing loss 1 | 123
Congenital anomaly of testis 1 | 52
Congenital deafness 1 | 185
Cupped ears (finding) 1 | 17
Deafness 1 | 198
Decreased IgM 1 | 11
Depressed cheekbone 1 | 22
Diarrhea 1 | 253
Difficulties with night vision 1 | 87
Erythema 1 | 58
Flattening of the zygomatic bone 1 | 22
Flushing 1 | 60
Fundus with peripheral 'bony spicules' 1 | 12
Hearing Loss, Partial 1 | 185
Hyperinsulinism 1 | 133
Hyperplasia of nose 1 | 23
Hypertrichosis 1 | 46
Hypertrophy of nose 1 | 23
Hypoplasia of the zygomatic bone 1 | 22
Hypotrophic cheekbone 1 | 22
Hypotrophic malar bone 1 | 129
IgG Deficiency 1 | 22
Immunoglobulin A deficiency (disorder) 1 | 19
Increased chromosomal breakage 1 | 27
Keratoconus 1 | 113
Large nose 1 | 23
Long narrow head 1 | 75
Low Vision 1 | 174
Lymphoma 1 | 81
Malar flattening 1 | 129
Malignant Squamous Cell Neoplasm 1 | 17
Microcephaly 1 | 166
Narrow cranium shape 1 | 75
Narrow face 1 | 54
Narrow head shape 1 | 75
Narrow skull shape 1 | 75
Night Blindness 1 | 101
Night blindness, progressive 1 | 51
Ophthalmoplegia 1 | 106
Pallor of optic disc 1 | 39
Photodysphoria 1 | 121
Photophobia 1 | 121
Photosensitivity of skin 1 | 51
Prominent ear 1 | 56
Protruding ears 1 | 56
Recurrent respiratory infections 1 | 141
Retinal pigment epithelial abnormality 1 | 111
Roberts syndrome 1 | 15
Sensorineural Hearing Loss (disorder) 1 | 284
Simple syndactyly of toes, first web space 1 | 23
Sinusitis 1 | 65
Small cheekbone 1 | 22
Specific learning disability 1 | 47
Squamous cell carcinoma 1 | 129
Substance-Related Disorders 1 | 115
Thin face 1 | 54
Turridolichocephaly 1 | 75
Visual Impairment 1 | 174
Werner syndrome 1 | 29
Xeroderma pigmentosum group D 1 | 33
hearing impairment 1 | 199

Tissue

Blood and immune system 4 | 16,909
Cardiovascular System 4 | 15,192
Digestive Tract 4 | 17,369
Endocrine System 4 | 18,159
Female tissues 4 | 17,400
Liver and Pancreas 4 | 16,750
Male tissues 4 | 17,142
Nervous System 4 | 16,725
Respiratory system 4 | 16,393
Skin and soft tissues 4 | 17,230
Urinary Tract 4 | 16,678

Target Family

Enzyme 3 | 4,145
Non-IDG 1 | 12,091

GO Function

ATP-dependent helicase activit... 4 | 4
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
ATP-dependent RNA helicase DDX1 DDX1 Tbio Enzyme -1.66212 44.8 174
U5 small nuclear ribonucleoprotein 200 kDa helicase SNRNP200 Tbio Enzyme -1.71387 54.4 45
ATP-dependent DNA helicase DDX11 DDX11 Tbio Enzyme -1.05592 30.0 163
Bloom syndrome protein BLM Tchem Non-IDG -2.03028 104.1 314